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Growing scientific evidence for the indispensable role of environmental sustainability in sustainable development calls for appropriate frameworks and indicators for environmental sustainability assessment (ESA). In this paper, we operationalize and update the footprint-boundary ESA framework, with a particular focus on its methodological and application extensions to the national level. By using the latest datasets available, the planetary boundaries for carbon emissions, water use and land use are allocated to 28 selected countries in comparison to the corresponding environmental footprints. The environmental sustainability ratio (ESR)—an internationally comparable indicator representing the sustainability gap between contemporary anthropogenic interference and critical capacity thresholds—allows one to map the reserve or transgression of the nation-specific environmental boundaries. While the geographical distribution of the three ESRs varies across nations, in general, the worldwide unsustainability of carbon emissions is largely driven by economic development, while resource endowments play a more central role in explaining national performance on water and land use. The main value added of this paper is to provide concrete evidence of the usefulness of the proposed framework in allocating overall responsibility for environmental sustainability to sub-global scales and in informing policy makers about the need to prevent the planet’s environment from tipping into an undesirable state.

The uncontrolled growth of urban areas worldwide is pushing a substantial part of the urban population to the fringes of society, confining them to the unsecure and unhygienic settlements that we call “informal.” These settlements lack in intelligible layout and essential services and infrastructures, thus representing a challenging issue for policy makers and urban designers in the development of renewal programs and strategies. In order to support the facing of these issues through an on-site upgrade approach, this paper argues that walkability deeply affects the functioning of informal settlements, so as to propose that they can be identified as “proximal cities,” which expresses the idea that the vital space in informal settlements has soft boundaries and follows a fuzzy logic. A quantitative analysis, based on a configurational approach, and a qualitative analysis, focused on the morphologic features of the settlements, have been implemented. A comparison of the results shows that this approach is suitable to provide a deeper knowledge on informal settlement and informal society under the assumption of their strict mutual connection. A primal definition of proximal cities, suitable for describing some properties of autopoietic urban systems, emerges from the evidence-based relationships between their spatial and social features. In this respect, a case study has been proposed and discussed.

Background: Sodium oxybate (SMO) has been shown to be effective in the maintenance of abstinence (MoA) in alcohol-dependent patients in a series of small randomized controlled trials (RCTs). These results needed to be confirmed by a large trial investigating the treatment effect and its sustainability after medication discontinuation. Aims: To confirm the SMO effect on (sustained) MoA in detoxified alcohol-dependent patients. Methods: Large double-blind, randomized, placebo-controlled trial in detoxified adult alcohol-dependent outpatients (80% men) from 11 sites in four European countries. Patients were randomized to 6 months SMO (3.3–3.9 g/day) or placebo followed by a 6-month medication-free period. Primary outcome was the cumulative abstinence duration (CAD) during the 6-month treatment period defined as the number of days with no alcohol use. Secondary outcomes included CAD during the 12-month study period. Results: Of the 314 alcohol-dependent patients randomized, 154 received SMO and 160 received placebo. Based on the pre-specified fixed-effect two-way analysis of variance including the treatment-by-site interaction, SMO showed efficacy in CAD during the 6-month treatment period: mean difference +43.1 days, 95% confidence interval (17.6–68.5; p = 0.001). Since significant heterogeneity of effect across sites and unequal sample sizes among sites ( n = 3–66) were identified, a site-level random meta-analysis was performed with results supporting the pre-specified analysis: mean difference +32.4 days, p = 0.014. The SMO effect was sustained during the medication-free follow-up period. SMO was well-tolerated. Conclusions: Results of this large RCT in alcohol-dependent patients demonstrated a significant and clinically relevant sustained effect of SMO on CAD. Trial registration: ClinicalTrials.gov Identifier: NCT04648423

AbstractEarthworms may promote the biodegradation of polycyclic aromatic hydrocarbons (PAHs) in soil, but the mechanism through which they exert such influence is still unknown. To determine if the stimulation of PAH degradation by earthworms is related to changes in microbial communities, a microcosm experiment was conducted consisting of columns with natural uncontaminated soil covered with PAH‐contaminated dredge sediment. Columns without and with low and high Eisenia andrei densities were prepared. Organic matter and PAH content, microbial biomass, and dehydrogenase activity (DHA) were measured in soil and sediment over time. Biolog Ecoplate™ and polymerase chain reaction using denaturing gradient gel electrophoresis were used to evaluate changes in metabolic and structural diversity of the microbial community, respectively. Earthworm activity promoted PAH degradation in soil, which was significant for biphenyl, benzo[a]pyrene, and benzo[e]pyrene. Microbial biomass and DHA activity generally did not change over the experiment. Earthworm activity did change microbial community structure, but this did not affect its functioning in terms of carbon substrate consumption. Results suggest no relationship between changes in the microbial community by earthworm activity and increased PAH disappearance. The role of shifts in soil microbial community structure induced by earthworms in PAH removal needs further investigation. Environ. Toxicol. Chem. 2012;31:794–803. © 2011 SETAC

In recent years there has been increasing attention to the transition toward a bioeconomy. From comparable transitions toward sustainability, we know that transitions require integral, inclusive approaches toward developing a long-term strategy, focusing not only on technological innovation, but also on involving the public. This is not easy. Public engagement encompasses diverse forms of public and civil society participation, and it is crucial to understand the specificities of these interactions and their effects on potential transition pathways. We present a conceptual-analytical paper where the focus lies on understanding sense-making practices in the construction of publics in the bioeconomy. Using a case-study approach, this article describes five partialities of the constructed public in the bioeconomy and analyzes the orchestration, productive dimensions and effects of these constructions. Our analysis offers a new perspective on, and appreciation of, the partiality of different forms of public participation, and varying degrees in which possibilities of system change in the bioeconomy transition are inclusive or exclusive toward differentially constructed publics. This offers an alternative, constructive way of exploring actor dynamics and politics in system change. We aim to contribute to a more nuanced and integral interpretation of public engagement in sustainability transitions, which is relevant to actors from academia, policy, industry and other spheres relevant to the bioeconomy transition.

There are substantial differences in carbon footprints across households. This study applied an environmentally extended multiregional input–output approach to estimate household carbon footprints for 12 different income groups of China’s 30 regions. Subsequently, carbon footprint Gini coefficients were calculated to measure carbon inequality for households across provinces. We found that the top 5% of income earners were responsible for 17% of the national household carbon footprint in 2012, while the bottom half of income earners caused only 25%. Carbon inequality declined with economic growth in China across space and time in two ways: first, carbon footprints showed greater convergence in the wealthier coastal regions than in the poorer inland regions; second, China’s national carbon footprint Gini coefficients declined from 0.44 in 2007 to 0.37 in 2012. We argue that economic growth not only increases income levels but also contributes to an overall reduction in carbon inequality in China.

Abstract An assessment of the human impact on the global water cycle requires estimating the volume of water withdrawn for irrigated agriculture. A key parameter in this calculation is the irrigation efficiency, which corrects for the fraction of water lost between irrigation withdrawals and the crop due to management, distribution or conveyance losses. Here we show that the irrigation efficiency used in global irrigation models is flawed for it overlooks key ambiguities in partial efficiencies, irrigation technologies, the definition of ‘large-scale’ irrigated areas or managerial factors. Once accounted for, these uncertainties can make irrigation withdrawal estimates fluctuate by more than one order of magnitude at the country level. Such variability is larger and leads to more extreme values than that caused by the uncertainties related with climate change. Our results highlight the need to embrace deep uncertainties in irrigation efficiency to prevent the design of shortsighted policies at the river basin-water-agricultural interface.