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Twenty-minute neighbourhoods highlight the importance of well-connected and mixed-used neighbourhoods and communities with proximate access to employment, essential services, public transport, and open spaces. Shorter distances together with re-prioritised public spaces encourage more active transport choices, resulting in public health benefits and reduced environmental pollution. Higher liveability brought about by mixed-use developments enables people to have equitable access to local facilities, amenities, and employment opportunities, promoting vibrancy, social cohesion, and intergenerational connections. The attributes of 20-minute neighbourhoods also combine to create places, that are acknowledged as friendly for all ages, address changing needs across the life course, and provide better support for the ageing population. Furthermore, there are indications that 20-minute neighbourhoods may be more resilient against many of the negative impacts of stringent public health protocols such as those implemented in periods of lockdown during the Covid-19 pandemic. In this article, we evaluate and compare planning policies and practices aimed at establishing 20-minute neighbourhoods in Melbourne (Australia) and Scotland (the UK). Using case studies, we discuss similarities and differences involved in using place-based approaches of 20-minute neighbourhoods to address 21st-century challenges in key areas of health and wellbeing, equity, environmental sustainability, and community resilience.

ABSTRACTA novel design for a high temperature SOFC, based on lamellar electrode-electrolyte segments obtained by solidification of an oxidic eutectic melt on an electrolyte substrate is presented. Such “composite” electrodes contain NiO or MnO - 8Y-ZrO2 lamellae, which after reduction / oxidation yield electrode-electrolyte lamellae with 1–2 μm width and a vertical dimension of> 100 μm, depending upon the amount of eutectic melt solidified on a polycrystalline substrate. The nucleation of the eutectic on a polycrystalline substrate followed by a semi-directional crystallization of the two phases yields a gradient of 3-phase boundaries over the height of such an electrode, with the number of 3-phase boundaries increasing towards the substrate.

Abstract As the part of a study to develop buparvaquone (BPQ) formulations for the treatment of cutaneous leishmaniasis, the topical delivery of BPQ and one of its prodrugs from a range of formulations was evaluated. In previous studies, BPQ and its prodrugs were shown to be potent antileishmanials in-vitro, with ED50 values in the nanomolar range. 3-Phosphono-oxymethyl-buparvaquone (3-POM-BPQ) was the most potent antileishmanial and was chosen, together with the parent drug, for further investigation. The ability of the parent and prodrug formulations to cross human and murine skin was tested in-vitro using the Franz diffusion cells. Formulations intended for topical application containing either BPQ or 3-POM-BPQ were developed using excipients that were either acceptable for topical use (GRAS or FDA inactive ingredients) or currently going through the regulatory process. BPQ was shown to penetrate both human epidermal membranes and full thickness BALB/c skin from a range of formulations (gels, emulsions). Similarly, 3-POM-BPQ penetrated full-thickness BALB/c skin from several gel formulations. In-vitro binding studies showed that BPQ bound melanin in a dose-dependent manner and preferably bound to delipidized skin over untreated BALB/c skin (on a weight to weight basis). The results confirm that BPQ and its prodrug 3-POM-BPQ can penetrate the skin from several formulations, making them potentially interesting candidates for further investigation of topical formulations using in-vivo models of cutaneous leishmaniasis.

SUMMARYThis article discusses how decentralisation policies are enacted in the planning and implementation of natural resource management interventions in rural Ethiopia. A key element of decentralisation policy is the emphasis on greater participation by local communities. Drawing on qualitative research conducted with government staff and farmers, this paper illustrates how different actors perceive and implement national policy and how these actions affect the longer‐term sustainability of land management interventions. Copyright © 2014 John Wiley & Sons, Ltd.

With the fast growth of the global economy, energy supply and demand have a strong impact on social, economic, and environmental aspects. As a consequence, this has pushed the decision-makers to formulate objectives, guiding economic policies toward sustainable goals. The process is known as Sustainable Development Goals (SDGs) that have been proposed by the United Nations. This being said, the energy sector is a vital domain with a vast potential for improvments in terms of technologies and ligistalations. Solar energy is among the most efficient solutions proposed to reduce the economic and environmental footprints of energy. In this frame, the current paper aims to localize solar energy within SDGs and analyze the contribution of the solar energy towards the achievement of the SDGs. Moreover, the current work highlights the contributions of Mohammed bin Rashid Al Maktoum (MBR) Solar Park in the United Arab Emirates to achieving the SDGs. Indeed, the MBR Solar Park concept offers valuable insights of environmental impacts by deploying clean and affordable energy sources in place of conventional fossil fuel power plants that are still heavily used in the region. The MBR Solar Park operation has already mitigated 6.5 million tonnes of carbon dioxide equivalent and this number will likely rise when all phases are installed and operational. Moreover, it has been shown that MBR Solar Park achieve several SDGs such SDG 8: decent work and economic growth, SDG 9: industry, innovation and infrastructure, SDG 11: sustainable cities and communities, and SDG 15: life on land.

Xuanwei City (formerly known as Xuanwei County) locates in the northeastern of Yunnan Province and is rich in coal, iron, copper and other mines, especially the smoky (bituminous) coal. Unfortunately, the lung cancer morbidity and mortality rates in this region are among China's highest, with a clear upward trend from the mid-1970s to mid-2000s. In 2004-2005, the crude death rate of lung cancer was 91.3 per 100,000 in the whole Xuanwei City, while that for Laibin Town in this city was 241.14 per 100,000. The epidemiologic distribution (clustering patterns by population, time, and space) of lung cancer in Xuanwei has some special features, e.g., high incidence in rural areas, high incidence in females, and an early age peak in lung cancer deaths. The main factor that associates with a high rate of lung cancer incidence was found to be indoor air pollution caused by the indoor burning of smoky coal. To a certain extent, genetic defects are also associated with the high incidence of lung cancer in Xuanwei. Taken together, lung cancer in this smoky coal combustion region is a unique model for environmental factor-related human cancer, and the current studies indicate that abandoning the use of smoky coal is the key to diminish lung cancer morbidity and mortality.

In developing an algal treatment system, selenium (Se) removal efficiency by Chlorella vulgaris was evaluated under various conditions such as Se concentration, algal density, temperature and pH. A maximum removal efficiency plateau of ∼90% was observed between 1000-3000 μg Se/L while the tolerance of Se toxicity was found at 6000 μg Se/L. C. vulgaris of 0.75 g DW/L showed the highest removal efficiency (84%), and volatilization was dominant below 1.37 g DW/L. Se volatilization was two times higher at 25 °C than at 20 °C in the first 24 h. Moreover, the highest removal efficiency (77%) was obtained at pH 8.0, compared to 66.5% at pH 6.5 and 40% at pH 10.0. To prevent ecotoxicity, Se laden algae were further burned to ashes or filtered out by Anodonta woodiana. After burning, biomass Se was reduced by 99%, with organo-Se entirely converted into inorganic Se, lowering Se bioavailability. A. woodiana removed 54% of Se in 24 h, leading to Se bioaccumulation in soft tissues, which may serve as dietary Se supplements for human health. Our results suggest the cleanup of Se-contaminated water from either agricultural runoff or industrial discharge could be achieved using an algal treatment system with minimum potential ecotoxicity.

Exploring the sensitivity of rural households’ livelihood strategies to livelihood capital is of great significance for improving rural households’ livelihood levels. This paper selects 23 livelihood capital measurement indicators and conducts an in-depth survey of rural households. In addition, the entropy method and a weighted comprehensive model are used to explore the basic characteristics of rural households’ livelihood capital in the upper reaches of the Min River, China, in 2017. Furthermore, econometric models are used to analyze the sensitivity of rural households’ livelihood strategies to livelihood capital. As indicated from the research, the livelihood capital levels of different types of rural households in the study area are not equivalent. The types of rural households with different livelihood strategies can be ordered in terms of quantity as follows: non-agricultural type > non-agricultural dominant type > agricultural dominant type > pure agricultural type. Livelihood strategies have different sensitivities to different livelihood capital measurement indicators. Among these indicators, cash income, the number of relatives and friends available for financial assistance, and the number of civil servants have positive effects on the livelihood strategy selection of non-agricultural dominant rural households and non-agricultural rural households. However, the average age of laborers, area of cultivated land and gardens, number of livestock and poultry, and present value of production tools have negative effects. These evaluation results can provide a scientific decision-making basis for the formulation of poverty alleviation policies by relevant government departments.