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Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dedup_wf_002::7b1901e490841f2d5701716e2afd987f&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Access Routes
Green 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dedup_wf_002::7b1901e490841f2d5701716e2afd987f&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu 
B. Arranz; I. Oteiza; 
E. Delgado; E. Delgado
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesE. Delgado in OpenAIRE A. Gutiérrez; A. Gutiérrez
Harvested from ORCID Public Data FileA. Gutiérrez in OpenAIREEl proyecto REVen “Rehabilitación energética de viviendas sociales, aplicando productos innovadores de ventana con marcado CE” (BIA2014-56650-JIN), tiene como objetivo realizar un análisis integral del impacto de la ventana en los aspectos relativos a eficiencia energética y calidad ambiental. Para caracterizar los flujos de energía y las condiciones ambientales internas se ha construido el Laboratorio REVen. Este artículo describe la construcción y la monitorización de este laboratorio analizando los datos de su primer año de funcionamiento. Los resultados permiten afirmar que se logra una mejora significativa del confort térmico obteniendo un ahorro de energía anual del 25 %.
Access RoutesGreen gold add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3989/ic.67523&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu- B. Arranz; I. Oteiza; E. Delgado;
E. Delgado
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesE. Delgado in OpenAIRE A. Gutiérrez; A. Gutiérrez
Harvested from ORCID Public Data FileA. Gutiérrez in OpenAIREEl proyecto REVen “Rehabilitación energética de viviendas sociales, aplicando productos innovadores de ventana con marcado CE” (BIA2014-56650-JIN), tiene como objetivo realizar un análisis integral del impacto de la ventana en los aspectos relativos a eficiencia energética y calidad ambiental. Para caracterizar los flujos de energía y las condiciones ambientales internas se ha construido el Laboratorio REVen. Este artículo describe la construcción y la monitorización de este laboratorio analizando los datos de su primer año de funcionamiento. Los resultados permiten afirmar que se logra una mejora significativa del confort térmico obteniendo un ahorro de energía anual del 25 %.
Access RoutesGreen gold add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3989/ic.67523&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Pilar Mercader-Moyano;
Pilar Mercader-Moyano
Harvested from ORCID Public Data FilePilar Mercader-Moyano in OpenAIRE Antonio Serrano-Jiménez; Antonio Serrano-Jiménez
Harvested from ORCID Public Data FileAntonio Serrano-Jiménez in OpenAIREThroughout the 21st century, urban reports demand solutions to the obsolescence and aging process suffered by the existing buildings, due to the growth and expansion of cities that took place in the second half of the 20th century [...]
Access Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/su132111850&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Pilar Mercader-Moyano;
Pilar Mercader-Moyano
Harvested from ORCID Public Data FilePilar Mercader-Moyano in OpenAIRE Antonio Serrano-Jiménez; Antonio Serrano-Jiménez
Harvested from ORCID Public Data FileAntonio Serrano-Jiménez in OpenAIREThroughout the 21st century, urban reports demand solutions to the obsolescence and aging process suffered by the existing buildings, due to the growth and expansion of cities that took place in the second half of the 20th century [...]
Access Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/su132111850&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - FWF| Nucleosynthesis in the lab-neutron-capture on Fe and Ni Guerrero C.;
Guerrero C.
Harvested from ORCID Public Data FileGuerrero C. in OpenAIRE Becares V.; Becares V.
Harvested from ORCID Public Data FileBecares V. in OpenAIRE Cano Ott D.; Fernandez Ordonez M.; +72 AuthorsCano Ott D.
Harvested from ORCID Public Data FileCano Ott D. in OpenAIRE Guerrero C.; Guerrero C.
Harvested from ORCID Public Data FileGuerrero C. in OpenAIRE Becares V.; Becares V.
Harvested from ORCID Public Data FileBecares V. in OpenAIRE Cano Ott D.; Fernandez Ordonez M.;Cano Ott D.
Harvested from ORCID Public Data FileCano Ott D. in OpenAIRE Gonzalez Romero E.; Martin Fuertes F.;Gonzalez Romero E.
Harvested from ORCID Public Data FileGonzalez Romero E. in OpenAIRE Martinez T.; Martinez T.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesMartinez T. in OpenAIRE Mendoza E.; Pina G.; Quinones J.; Vlachoudis V.;Mendoza E.
Harvested from ORCID Public Data FileMendoza E. in OpenAIRE Calviani M.; Andriamonje S.; Brugger M.; Cerutti F.; Chiaveri E.; Ferrari A.; Kadi Y.; Lebbos E.; Berthoumieux E.; Gunsing F.;Calviani M.
Harvested from ORCID Public Data FileCalviani M. in OpenAIRE Andrzejewski J.; Andrzejewski J.
Harvested from ORCID Public Data FileAndrzejewski J. in OpenAIRE Marganiec J.; Marganiec J.
Harvested from ORCID Public Data FileMarganiec J. in OpenAIRE Perkowski J.; Perkowski J.
Harvested from ORCID Public Data FilePerkowski J. in OpenAIRE Audouin L.; Berthier B.; Tassan Got L.;Audouin L.
Harvested from ORCID Public Data FileAudouin L. in OpenAIRE Avrigeanu V.; Avrigeanu V.
Harvested from ORCID Public Data FileAvrigeanu V. in OpenAIRE Mirea M.; Becvar F.; Krticka M.; Belloni F.; M. Milazzo P.; Calvino F.; Calvino F.
Harvested from ORCID Public Data FileCalvino F. in OpenAIRE Cortes G.; B. Gomez Hornillos M.; Carrapico C.;B. Gomez Hornillos M.
Harvested from ORCID Public Data FileB. Gomez Hornillos M. in OpenAIRE F. Goncalves I.; F. Goncalves I.
Harvested from ORCID Public Data FileF. Goncalves I. in OpenAIRE Sarmento R.; Sarmento R.
Harvested from ORCID Public Data FileSarmento R. in OpenAIRE Vaz P.; Colonna N.; Marrone S.; Moinul M.; Tagliente G.; Variale V.; Dillmann I.; Dillmann I.
Harvested from ORCID Public Data FileDillmann I. in OpenAIRE Domingo Pardo C.; Heil M.; Duran I.;Domingo Pardo C.
Harvested from ORCID Public Data FileDomingo Pardo C. in OpenAIRE Paradela C.; Paradela C.
Harvested from ORCID Public Data FileParadela C. in OpenAIRE Tarrio D.; Ganesan S.; Giubrone G.; L. Tain J.; L. Tain J.
Harvested from ORCID Public Data FileL. Tain J. in OpenAIRE Gramegna F.; F. Mastinu P.; Harrisopulos S.; Ioannides K.; Karadimos D.;Gramegna F.
Harvested from ORCID Public Data FileGramegna F. in OpenAIRE Jericha E.; Leeb H.; Weiss C.; Kappeler F.; Lederer C.;Jericha E.
Harvested from ORCID Public Data FileJericha E. in OpenAIRE Pavlik A.; Wallner A.; Wallner A.
Harvested from ORCID Public Data FileWallner A. in OpenAIRE Lozano M.; Praena J.; M. Quesada J.; M. Quesada J.
Harvested from ORCID Public Data FileM. Quesada J. in OpenAIRE MASSIMI, CRISTIAN; MASSIMI, CRISTIAN
Harvested from ORCID Public Data FileMASSIMI, CRISTIAN in OpenAIRE VANNINI, GIANNI; VANNINI, GIANNI
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesVANNINI, GIANNI in OpenAIRE Mengoni A.; Mengoni A.
Harvested from ORCID Public Data FileMengoni A. in OpenAIRE Ventura A.; Mosconi M.; Nolte R.; Vlastou R.;Ventura A.
Harvested from ORCID Public Data FileVentura A. in OpenAIREAfter a halt of four years, the n TOF spallation neutron facility at CERN has resumed operation in November 2008 with a new spallation target characterized by an improved safety and engineering design, resulting in a more robust overall performance and e cient cooling. The rst measurement during the 2009 run has aimed at the full characterization of the neutron beam. Several detectors, such as calibrated ssion chambers, the n TOF Silicon Monitor, a Mi- croMegas detector with 10B and 235U samples, as well as liquid and solid scintillators have been used in order to characterize the properties of the neutron uence. The spatial pro le of the beam has been studied with a specially designed \X-Y
Access RoutesGreen add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3938/jkps.59.1624&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - FWF| Nucleosynthesis in the lab-neutron-capture on Fe and Ni Guerrero C.;
Guerrero C.
Harvested from ORCID Public Data FileGuerrero C. in OpenAIRE Becares V.; Becares V.
Harvested from ORCID Public Data FileBecares V. in OpenAIRE Cano Ott D.; Fernandez Ordonez M.; +72 AuthorsCano Ott D.
Harvested from ORCID Public Data FileCano Ott D. in OpenAIRE Guerrero C.; Guerrero C.
Harvested from ORCID Public Data FileGuerrero C. in OpenAIRE Becares V.; Becares V.
Harvested from ORCID Public Data FileBecares V. in OpenAIRE Cano Ott D.; Fernandez Ordonez M.;Cano Ott D.
Harvested from ORCID Public Data FileCano Ott D. in OpenAIRE Gonzalez Romero E.; Martin Fuertes F.;Gonzalez Romero E.
Harvested from ORCID Public Data FileGonzalez Romero E. in OpenAIRE Martinez T.; Martinez T.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesMartinez T. in OpenAIRE Mendoza E.; Pina G.; Quinones J.; Vlachoudis V.;Mendoza E.
Harvested from ORCID Public Data FileMendoza E. in OpenAIRE Calviani M.; Andriamonje S.; Brugger M.; Cerutti F.; Chiaveri E.; Ferrari A.; Kadi Y.; Lebbos E.; Berthoumieux E.; Gunsing F.;Calviani M.
Harvested from ORCID Public Data FileCalviani M. in OpenAIRE Andrzejewski J.; Andrzejewski J.
Harvested from ORCID Public Data FileAndrzejewski J. in OpenAIRE Marganiec J.; Marganiec J.
Harvested from ORCID Public Data FileMarganiec J. in OpenAIRE Perkowski J.; Perkowski J.
Harvested from ORCID Public Data FilePerkowski J. in OpenAIRE Audouin L.; Berthier B.; Tassan Got L.;Audouin L.
Harvested from ORCID Public Data FileAudouin L. in OpenAIRE Avrigeanu V.; Avrigeanu V.
Harvested from ORCID Public Data FileAvrigeanu V. in OpenAIRE Mirea M.; Becvar F.; Krticka M.; Belloni F.; M. Milazzo P.; Calvino F.; Calvino F.
Harvested from ORCID Public Data FileCalvino F. in OpenAIRE Cortes G.; B. Gomez Hornillos M.; Carrapico C.;B. Gomez Hornillos M.
Harvested from ORCID Public Data FileB. Gomez Hornillos M. in OpenAIRE F. Goncalves I.; F. Goncalves I.
Harvested from ORCID Public Data FileF. Goncalves I. in OpenAIRE Sarmento R.; Sarmento R.
Harvested from ORCID Public Data FileSarmento R. in OpenAIRE Vaz P.; Colonna N.; Marrone S.; Moinul M.; Tagliente G.; Variale V.; Dillmann I.; Dillmann I.
Harvested from ORCID Public Data FileDillmann I. in OpenAIRE Domingo Pardo C.; Heil M.; Duran I.;Domingo Pardo C.
Harvested from ORCID Public Data FileDomingo Pardo C. in OpenAIRE Paradela C.; Paradela C.
Harvested from ORCID Public Data FileParadela C. in OpenAIRE Tarrio D.; Ganesan S.; Giubrone G.; L. Tain J.; L. Tain J.
Harvested from ORCID Public Data FileL. Tain J. in OpenAIRE Gramegna F.; F. Mastinu P.; Harrisopulos S.; Ioannides K.; Karadimos D.;Gramegna F.
Harvested from ORCID Public Data FileGramegna F. in OpenAIRE Jericha E.; Leeb H.; Weiss C.; Kappeler F.; Lederer C.;Jericha E.
Harvested from ORCID Public Data FileJericha E. in OpenAIRE Pavlik A.; Wallner A.; Wallner A.
Harvested from ORCID Public Data FileWallner A. in OpenAIRE Lozano M.; Praena J.; M. Quesada J.; M. Quesada J.
Harvested from ORCID Public Data FileM. Quesada J. in OpenAIRE MASSIMI, CRISTIAN; MASSIMI, CRISTIAN
Harvested from ORCID Public Data FileMASSIMI, CRISTIAN in OpenAIRE VANNINI, GIANNI; VANNINI, GIANNI
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesVANNINI, GIANNI in OpenAIRE Mengoni A.; Mengoni A.
Harvested from ORCID Public Data FileMengoni A. in OpenAIRE Ventura A.; Mosconi M.; Nolte R.; Vlastou R.;Ventura A.
Harvested from ORCID Public Data FileVentura A. in OpenAIREAfter a halt of four years, the n TOF spallation neutron facility at CERN has resumed operation in November 2008 with a new spallation target characterized by an improved safety and engineering design, resulting in a more robust overall performance and e cient cooling. The rst measurement during the 2009 run has aimed at the full characterization of the neutron beam. Several detectors, such as calibrated ssion chambers, the n TOF Silicon Monitor, a Mi- croMegas detector with 10B and 235U samples, as well as liquid and solid scintillators have been used in order to characterize the properties of the neutron uence. The spatial pro le of the beam has been studied with a specially designed \X-Y
Access RoutesGreen add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3938/jkps.59.1624&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - EC| NextGen IO ,NIH| Liver-enriched Transcription Factors as Prognostic Markers and Therapeutic Targets in Alcoholic Hepatitis Goikoetxea-Usandizaga, Naroa;
Goikoetxea-Usandizaga, Naroa
Harvested from ORCID Public Data FileGoikoetxea-Usandizaga, Naroa in OpenAIRE Bravo, Miren; Bravo, Miren
Harvested from ORCID Public Data FileBravo, Miren in OpenAIRE Egia-Mendikute, Leire; Egia-Mendikute, Leire
Harvested from ORCID Public Data FileEgia-Mendikute, Leire in OpenAIRE Abecia, Leticia; +38 AuthorsAbecia, Leticia
Harvested from ORCID Public Data FileAbecia, Leticia in OpenAIRE Goikoetxea-Usandizaga, Naroa; Goikoetxea-Usandizaga, Naroa
Harvested from ORCID Public Data FileGoikoetxea-Usandizaga, Naroa in OpenAIRE Bravo, Miren; Bravo, Miren
Harvested from ORCID Public Data FileBravo, Miren in OpenAIRE Egia-Mendikute, Leire; Egia-Mendikute, Leire
Harvested from ORCID Public Data FileEgia-Mendikute, Leire in OpenAIRE Abecia, Leticia; Abecia, Leticia
Harvested from ORCID Public Data FileAbecia, Leticia in OpenAIRE Serrano-Maciá, Marina; Urdinguio, Rocío G.;Serrano-Maciá, Marina
Harvested from ORCID Public Data FileSerrano-Maciá, Marina in OpenAIRE Clos-García, Marc; Clos-García, Marc
Harvested from ORCID Public Data FileClos-García, Marc in OpenAIRE Rodríguez-Agudo, Rubén; Rodríguez-Agudo, Rubén
Harvested from ORCID Public Data FileRodríguez-Agudo, Rubén in OpenAIRE Araujo-Legido, Raquel; Araujo-Legido, Raquel
Harvested from ORCID Public Data FileAraujo-Legido, Raquel in OpenAIRE López-Bermudo, Lucía; López-Bermudo, Lucía
Harvested from ORCID Public Data FileLópez-Bermudo, Lucía in OpenAIRE Delgado, Teresa C.; Delgado, Teresa C.
Harvested from ORCID Public Data FileDelgado, Teresa C. in OpenAIRE Lachiondo-Ortega, Sofía; Lachiondo-Ortega, Sofía
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesLachiondo-Ortega, Sofía in OpenAIRE González-Recio, Irene; González-Recio, Irene
Harvested from ORCID Public Data FileGonzález-Recio, Irene in OpenAIRE Gil-Pitarch, Clàudia; Gil-Pitarch, Clàudia
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesGil-Pitarch, Clàudia in OpenAIRE Peña-Cearra, Ainize; Peña-Cearra, Ainize
Harvested from ORCID Public Data FilePeña-Cearra, Ainize in OpenAIRE Simón, Jorge; Simón, Jorge
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesSimón, Jorge in OpenAIRE Benedé-Ubieto, Raquel; Ariño, Silvia;Benedé-Ubieto, Raquel
Harvested from ORCID Public Data FileBenedé-Ubieto, Raquel in OpenAIRE Herranz, Jose M.; Herranz, Jose M.
Harvested from ORCID Public Data FileHerranz, Jose M. in OpenAIRE Azkargorta, Mikel; Azkargorta, Mikel
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesAzkargorta, Mikel in OpenAIRE Salazar-Bermeo, Julio; Salazar-Bermeo, Julio
Harvested from ORCID Public Data FileSalazar-Bermeo, Julio in OpenAIRE Martí, Nuria; Martí, Nuria
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesMartí, Nuria in OpenAIRE Varela-Rey, Marta; Varela-Rey, Marta
Harvested from ORCID Public Data FileVarela-Rey, Marta in OpenAIRE Falcón-Pérez, Juan M.; Falcón-Pérez, Juan M.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesFalcón-Pérez, Juan M. in OpenAIRE Lorenzo, Óscar; Lorenzo, Óscar
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesLorenzo, Óscar in OpenAIRE Nogueiras, Rubén; Nogueiras, Rubén
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesNogueiras, Rubén in OpenAIRE Elortza, Félix; Elortza, Félix
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesElortza, Félix in OpenAIRE Nevzorova, Yulia; Nevzorova, Yulia
Harvested from ORCID Public Data FileNevzorova, Yulia in OpenAIRE Cubero, Francisco J.; Cubero, Francisco J.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesCubero, Francisco J. in OpenAIRE Saura, Domingo; Saura, Domingo
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesSaura, Domingo in OpenAIRE Martínez-Cruz, Luis Alfonso; Martínez-Cruz, Luis Alfonso
Harvested from ORCID Public Data FileMartínez-Cruz, Luis Alfonso in OpenAIRE Sabio, Guadalupe; Sabio, Guadalupe
Harvested from ORCID Public Data FileSabio, Guadalupe in OpenAIRE Palazón, Asís; Palazón, Asís;Palazón, Asís
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesPalazón, Asís in OpenAIRE Sancho-Bru, Pau; Sancho-Bru, Pau
Harvested from ORCID Public Data FileSancho-Bru, Pau in OpenAIRE Elguezabal, Natalia; Elguezabal, Natalia
Harvested from ORCID Public Data FileElguezabal, Natalia in OpenAIRE Fraga, Mario F.; Fraga, Mario F.
Harvested from ORCID Public Data FileFraga, Mario F. in OpenAIRE Ávila, Matías A.; Bataller, Ramón;Ávila, Matías A.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesÁvila, Matías A. in OpenAIRE Marín, José J. G.; Marín, José J. G.
Harvested from ORCID Public Data FileMarín, José J. G. in OpenAIRE Martín, Franz; Martín, Franz
Harvested from ORCID Public Data FileMartín, Franz in OpenAIRE Martínez-Chantar, María Luz; Martínez-Chantar, María Luz
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesMartínez-Chantar, María Luz in OpenAIREBackground and Aims: Alcohol-associated liver disease (ALD) accounts for 70% of liver-related deaths in Europe, with no effective approved therapies. Although mitochondrial dysfunction is one of the earliest manifestations of alcohol-induced injury, restoring mitochondrial activity remains a problematic strategy due to oxidative stress. Here, we identify methylation-controlled J protein (MCJ) as a mediator for ALD progression and hypothesize that targeting MCJ may help in recovering mitochondrial fitness without collateral oxidative damage. Approach and Results: C57BL/6 mice [wild-type (Wt)] Mcj knockout and Mcj liver-specific silencing (MCJ-LSS) underwent the NIAAA dietary protocol (Lieber-DeCarli diet containing 5% (vol/vol) ethanol for 10 days, plus a single binge ethanol feeding at day 11). To evaluate the impact of a restored mitochondrial activity in ALD, the liver, gut, and pancreas were characterized, focusing on lipid metabolism, glucose homeostasis, intestinal permeability, and microbiota composition. MCJ, a protein acting as an endogenous negative regulator of mitochondrial respiration, is downregulated in the early stages of ALD and increases with the severity of the disease. Whole-body deficiency of MCJ is detrimental during ALD because it exacerbates the systemic effects of alcohol abuse through altered intestinal permeability, increased endotoxemia, and dysregulation of pancreatic function, which overall worsens liver injury. On the other hand, liver-specific Mcj silencing prevents main ALD hallmarks, that is, mitochondrial dysfunction, steatosis, inflammation, and oxidative stress, as it restores the NAD+/NADH ratio and SIRT1 function, hence preventing de novo lipogenesis and improving lipid oxidation. Conclusions: Improving mitochondrial respiration by liver-specific Mcj silencing might become a novel therapeutic approach for treating ALD.
Access RoutesGreen hybrid add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1097/hep.0000000000000303&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - EC| NextGen IO ,NIH| Liver-enriched Transcription Factors as Prognostic Markers and Therapeutic Targets in Alcoholic Hepatitis Goikoetxea-Usandizaga, Naroa;
Goikoetxea-Usandizaga, Naroa
Harvested from ORCID Public Data FileGoikoetxea-Usandizaga, Naroa in OpenAIRE Bravo, Miren; Bravo, Miren
Harvested from ORCID Public Data FileBravo, Miren in OpenAIRE Egia-Mendikute, Leire; Egia-Mendikute, Leire
Harvested from ORCID Public Data FileEgia-Mendikute, Leire in OpenAIRE Abecia, Leticia; +38 AuthorsAbecia, Leticia
Harvested from ORCID Public Data FileAbecia, Leticia in OpenAIRE Goikoetxea-Usandizaga, Naroa; Goikoetxea-Usandizaga, Naroa
Harvested from ORCID Public Data FileGoikoetxea-Usandizaga, Naroa in OpenAIRE Bravo, Miren; Bravo, Miren
Harvested from ORCID Public Data FileBravo, Miren in OpenAIRE Egia-Mendikute, Leire; Egia-Mendikute, Leire
Harvested from ORCID Public Data FileEgia-Mendikute, Leire in OpenAIRE Abecia, Leticia; Abecia, Leticia
Harvested from ORCID Public Data FileAbecia, Leticia in OpenAIRE Serrano-Maciá, Marina; Urdinguio, Rocío G.;Serrano-Maciá, Marina
Harvested from ORCID Public Data FileSerrano-Maciá, Marina in OpenAIRE Clos-García, Marc; Clos-García, Marc
Harvested from ORCID Public Data FileClos-García, Marc in OpenAIRE Rodríguez-Agudo, Rubén; Rodríguez-Agudo, Rubén
Harvested from ORCID Public Data FileRodríguez-Agudo, Rubén in OpenAIRE Araujo-Legido, Raquel; Araujo-Legido, Raquel
Harvested from ORCID Public Data FileAraujo-Legido, Raquel in OpenAIRE López-Bermudo, Lucía; López-Bermudo, Lucía
Harvested from ORCID Public Data FileLópez-Bermudo, Lucía in OpenAIRE Delgado, Teresa C.; Delgado, Teresa C.
Harvested from ORCID Public Data FileDelgado, Teresa C. in OpenAIRE Lachiondo-Ortega, Sofía; Lachiondo-Ortega, Sofía
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesLachiondo-Ortega, Sofía in OpenAIRE González-Recio, Irene; González-Recio, Irene
Harvested from ORCID Public Data FileGonzález-Recio, Irene in OpenAIRE Gil-Pitarch, Clàudia; Gil-Pitarch, Clàudia
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesGil-Pitarch, Clàudia in OpenAIRE Peña-Cearra, Ainize; Peña-Cearra, Ainize
Harvested from ORCID Public Data FilePeña-Cearra, Ainize in OpenAIRE Simón, Jorge; Simón, Jorge
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesSimón, Jorge in OpenAIRE Benedé-Ubieto, Raquel; Ariño, Silvia;Benedé-Ubieto, Raquel
Harvested from ORCID Public Data FileBenedé-Ubieto, Raquel in OpenAIRE Herranz, Jose M.; Herranz, Jose M.
Harvested from ORCID Public Data FileHerranz, Jose M. in OpenAIRE Azkargorta, Mikel; Azkargorta, Mikel
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesAzkargorta, Mikel in OpenAIRE Salazar-Bermeo, Julio; Salazar-Bermeo, Julio
Harvested from ORCID Public Data FileSalazar-Bermeo, Julio in OpenAIRE Martí, Nuria; Martí, Nuria
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesMartí, Nuria in OpenAIRE Varela-Rey, Marta; Varela-Rey, Marta
Harvested from ORCID Public Data FileVarela-Rey, Marta in OpenAIRE Falcón-Pérez, Juan M.; Falcón-Pérez, Juan M.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesFalcón-Pérez, Juan M. in OpenAIRE Lorenzo, Óscar; Lorenzo, Óscar
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesLorenzo, Óscar in OpenAIRE Nogueiras, Rubén; Nogueiras, Rubén
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesNogueiras, Rubén in OpenAIRE Elortza, Félix; Elortza, Félix
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesElortza, Félix in OpenAIRE Nevzorova, Yulia; Nevzorova, Yulia
Harvested from ORCID Public Data FileNevzorova, Yulia in OpenAIRE Cubero, Francisco J.; Cubero, Francisco J.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesCubero, Francisco J. in OpenAIRE Saura, Domingo; Saura, Domingo
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesSaura, Domingo in OpenAIRE Martínez-Cruz, Luis Alfonso; Martínez-Cruz, Luis Alfonso
Harvested from ORCID Public Data FileMartínez-Cruz, Luis Alfonso in OpenAIRE Sabio, Guadalupe; Sabio, Guadalupe
Harvested from ORCID Public Data FileSabio, Guadalupe in OpenAIRE Palazón, Asís; Palazón, Asís;Palazón, Asís
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesPalazón, Asís in OpenAIRE Sancho-Bru, Pau; Sancho-Bru, Pau
Harvested from ORCID Public Data FileSancho-Bru, Pau in OpenAIRE Elguezabal, Natalia; Elguezabal, Natalia
Harvested from ORCID Public Data FileElguezabal, Natalia in OpenAIRE Fraga, Mario F.; Fraga, Mario F.
Harvested from ORCID Public Data FileFraga, Mario F. in OpenAIRE Ávila, Matías A.; Bataller, Ramón;Ávila, Matías A.
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesÁvila, Matías A. in OpenAIRE Marín, José J. G.; Marín, José J. G.
Harvested from ORCID Public Data FileMarín, José J. G. in OpenAIRE Martín, Franz; Martín, Franz
Harvested from ORCID Public Data FileMartín, Franz in OpenAIRE Martínez-Chantar, María Luz; Martínez-Chantar, María Luz
Derived by OpenAIRE algorithms or harvested from 3rd party repositoriesMartínez-Chantar, María Luz in OpenAIREBackground and Aims: Alcohol-associated liver disease (ALD) accounts for 70% of liver-related deaths in Europe, with no effective approved therapies. Although mitochondrial dysfunction is one of the earliest manifestations of alcohol-induced injury, restoring mitochondrial activity remains a problematic strategy due to oxidative stress. Here, we identify methylation-controlled J protein (MCJ) as a mediator for ALD progression and hypothesize that targeting MCJ may help in recovering mitochondrial fitness without collateral oxidative damage. Approach and Results: C57BL/6 mice [wild-type (Wt)] Mcj knockout and Mcj liver-specific silencing (MCJ-LSS) underwent the NIAAA dietary protocol (Lieber-DeCarli diet containing 5% (vol/vol) ethanol for 10 days, plus a single binge ethanol feeding at day 11). To evaluate the impact of a restored mitochondrial activity in ALD, the liver, gut, and pancreas were characterized, focusing on lipid metabolism, glucose homeostasis, intestinal permeability, and microbiota composition. MCJ, a protein acting as an endogenous negative regulator of mitochondrial respiration, is downregulated in the early stages of ALD and increases with the severity of the disease. Whole-body deficiency of MCJ is detrimental during ALD because it exacerbates the systemic effects of alcohol abuse through altered intestinal permeability, increased endotoxemia, and dysregulation of pancreatic function, which overall worsens liver injury. On the other hand, liver-specific Mcj silencing prevents main ALD hallmarks, that is, mitochondrial dysfunction, steatosis, inflammation, and oxidative stress, as it restores the NAD+/NADH ratio and SIRT1 function, hence preventing de novo lipogenesis and improving lipid oxidation. Conclusions: Improving mitochondrial respiration by liver-specific Mcj silencing might become a novel therapeutic approach for treating ALD.
Access RoutesGreen hybrid add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1097/hep.0000000000000303&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dedup_wf_002::63c785a05bf3c72c86ef23dcbc0fe1fb&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dedup_wf_002::63c785a05bf3c72c86ef23dcbc0fe1fb&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu- EC| VALOR-PLUSMiguel Valdivia; Jose Luis Galan;
Jose Luis Galan
Harvested from ORCID Public Data FileJose Luis Galan in OpenAIRE Joaquina Laffarga; Joaquina Laffarga
Harvested from ORCID Public Data FileJoaquina Laffarga in OpenAIRE Juan-Luis Ramos; Juan-Luis Ramos
Harvested from ORCID Public Data FileJuan-Luis Ramos in OpenAIRESummaryThe production of liquid biofuels to blend with gasoline is of worldwide importance to secure the energy supply while reducing the use of fossil fuels, supporting the development of rural technology with knowledge‐based jobs and mitigating greenhouse gas emissions. Today, engineering for plant construction is accessible and new processes using agricultural residues and municipal solid wastes have reached a good degree of maturity and high conversion yields (almost 90% of polysaccharides are converted into monosaccharides ready for fermentation). For the complete success of the 2G technology, it is still necessary to overcome a number of limitations that prevent a first‐of‐a‐kind plant from operating at nominal capacity. We also claim that the triumph of 2G technology requires the development of favourable logistics to guarantee biomass supply and make all actors (farmers, investors, industrial entrepreneurs, government, others) aware that success relies on agreement advances. The growth of ethanol production for 2020 seems to be secured with a number of 2G plants, but public/private investments are still necessary to enable 2G technology to move on ahead from its very early stages to a more mature consolidated technology.
Access RoutesGreen gold 207 citations 207 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/1751-7915.12387&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - EC| VALOR-PLUSMiguel Valdivia; Jose Luis Galan;
Jose Luis Galan
Harvested from ORCID Public Data FileJose Luis Galan in OpenAIRE Joaquina Laffarga; Joaquina Laffarga
Harvested from ORCID Public Data FileJoaquina Laffarga in OpenAIRE Juan-Luis Ramos; Juan-Luis Ramos
Harvested from ORCID Public Data FileJuan-Luis Ramos in OpenAIRESummaryThe production of liquid biofuels to blend with gasoline is of worldwide importance to secure the energy supply while reducing the use of fossil fuels, supporting the development of rural technology with knowledge‐based jobs and mitigating greenhouse gas emissions. Today, engineering for plant construction is accessible and new processes using agricultural residues and municipal solid wastes have reached a good degree of maturity and high conversion yields (almost 90% of polysaccharides are converted into monosaccharides ready for fermentation). For the complete success of the 2G technology, it is still necessary to overcome a number of limitations that prevent a first‐of‐a‐kind plant from operating at nominal capacity. We also claim that the triumph of 2G technology requires the development of favourable logistics to guarantee biomass supply and make all actors (farmers, investors, industrial entrepreneurs, government, others) aware that success relies on agreement advances. The growth of ethanol production for 2020 seems to be secured with a number of 2G plants, but public/private investments are still necessary to enable 2G technology to move on ahead from its very early stages to a more mature consolidated technology.
Access RoutesGreen gold 207 citations 207 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/1751-7915.12387&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/978-3-030-91084-6_5&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/978-3-030-91084-6_5&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu- Access Routes
Green 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dedup_wf_002::7139066d27778e639839683896139644&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Access Routes
Green 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dedup_wf_002::7139066d27778e639839683896139644&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Bejarano, Guillermo; Lemos, Joao M.; Ortega Linares, Manuel Gil; Rodríguez Rubio, Francisco;
Bejarano, Guillermo
Harvested from ORCID Public Data FileBejarano, Guillermo in OpenAIREXL Jornadas de automática. Ferrol 2019 Este trabajo aborda la gestión energética de un sistema formado por un ciclo de refrigeración y un tanque de almacenamiento de energía basado en materiales de cambio de fase, que se usa como reservorio de energía frigorífica y permite desacoplar la producci´on y la demanda de frío. Se aplica una estrategia de planificación y control en cascada, donde un planificador basado en control predictivo calcula las referencias para las principales potencias frigoríficas, mientras que un controlador de potencia regula las potencias generadas. El planificador considera criterios económicos, de eficiencia y de factibilidad para la generación de referencias, buscando minimizar el coste diario de operación. La estrategia propuesta se compara en simulación con una estrategia no predictiva, donde se muestra que la primera no solo logra satisfacer un perfil exigente de demanda que provoca el fracaso de la segunda estrategia, sino que también reduce el coste de operación. Ministerio de Economía, Industria y Competitividad DPI2016-79444-R.
Access RoutesGreen 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.17979/spudc.9788497497169.374&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Bejarano, Guillermo; Lemos, Joao M.; Ortega Linares, Manuel Gil; Rodríguez Rubio, Francisco;
Bejarano, Guillermo
Harvested from ORCID Public Data FileBejarano, Guillermo in OpenAIREXL Jornadas de automática. Ferrol 2019 Este trabajo aborda la gestión energética de un sistema formado por un ciclo de refrigeración y un tanque de almacenamiento de energía basado en materiales de cambio de fase, que se usa como reservorio de energía frigorífica y permite desacoplar la producci´on y la demanda de frío. Se aplica una estrategia de planificación y control en cascada, donde un planificador basado en control predictivo calcula las referencias para las principales potencias frigoríficas, mientras que un controlador de potencia regula las potencias generadas. El planificador considera criterios económicos, de eficiencia y de factibilidad para la generación de referencias, buscando minimizar el coste diario de operación. La estrategia propuesta se compara en simulación con una estrategia no predictiva, donde se muestra que la primera no solo logra satisfacer un perfil exigente de demanda que provoca el fracaso de la segunda estrategia, sino que también reduce el coste de operación. Ministerio de Economía, Industria y Competitividad DPI2016-79444-R.
Access RoutesGreen 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.17979/spudc.9788497497169.374&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu
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