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description Publicationkeyboard_double_arrow_right Article , Journal 2012 PeruPublisher:Elsevier BV Berrang-Ford, L.; Dingle, K.; Ford, J.D.; Lee, C.; Lwasa, S.; Namanya, D.B.; Henderson, J.; Llanos Cuentas, Elmer Alejandro; Cárcamo Cavagnaro, César Paul Eugenio; Edge, V.;The potential impacts of climate change on human health in sub-Saharan Africa are wide-ranging, complex, and largely adverse. The region's Indigenous peoples are considered to be at heightened risk given their relatively poor health outcomes, marginal social status, and resource-based livelihoods; however, little attention has been given to these most vulnerable of the vulnerable. This paper contributes to addressing this gap by taking a bottom-up approach to assessing health vulnerabilities to climate change in two Batwa Pygmy communities in rural Uganda. Rapid Rural Appraisal and PhotoVoice field methods complemented by qualitative data analysis were used to identify key climate-sensitive, community-identified health outcomes, describe determinants of sensitivity at multiple scales, and characterize adaptive capacity of Batwa health systems. The findings stress the importance of human drivers of vulnerability and adaptive capacity and the need to address social determinants of health in order to reduce the potential disease burden of climate change.
Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu84 citations 84 popularity Top 1% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2012 PeruPublisher:Elsevier BV Berrang-Ford, L.; Dingle, K.; Ford, J.D.; Lee, C.; Lwasa, S.; Namanya, D.B.; Henderson, J.; Llanos Cuentas, Elmer Alejandro; Cárcamo Cavagnaro, César Paul Eugenio; Edge, V.;The potential impacts of climate change on human health in sub-Saharan Africa are wide-ranging, complex, and largely adverse. The region's Indigenous peoples are considered to be at heightened risk given their relatively poor health outcomes, marginal social status, and resource-based livelihoods; however, little attention has been given to these most vulnerable of the vulnerable. This paper contributes to addressing this gap by taking a bottom-up approach to assessing health vulnerabilities to climate change in two Batwa Pygmy communities in rural Uganda. Rapid Rural Appraisal and PhotoVoice field methods complemented by qualitative data analysis were used to identify key climate-sensitive, community-identified health outcomes, describe determinants of sensitivity at multiple scales, and characterize adaptive capacity of Batwa health systems. The findings stress the importance of human drivers of vulnerability and adaptive capacity and the need to address social determinants of health in order to reduce the potential disease burden of climate change.
Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu84 citations 84 popularity Top 1% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2013 NetherlandsPublisher:Elsevier BV Authors: Harold J. Annegarn; Margaret Njirambo Matinga; Joy S. Clancy;pmid: 24161104
Policymakers at global level recognise that household biomass use in developing countries has significant health consequences. However, it is unclear how local-level health professionals perceive and respond to such health effects. This paper which is derived from the findings of a larger study on perceptions and responses to the harmful health effects of carrying heavy firewood loads and to smoke from cooking fires is based on a study conducted in South Africa among managers of health programmes and community nurses of Qaukeni and Mhlontlo municipalities in rural Eastern Cape. Interviews and participant observations were conducted in 2009 using ethnographic grounded theory approaches. In addition to a 10-month period of ethnographic fieldwork, ten programme managers and nurses in two villages were interviewed about health patterns in the villages that they serve, their perceptions of, and responses to the health effects of carrying heavy firewood loads, and inhalation of smoke from wood and dung cooking fires, their professional qualifications and experience, their own household energy use; and observations made as they served clinic clients. Results show that these programme managers and nurses perceive the health effects of carrying heavy loads of firewood and of cooking smoke as minor. Sometimes, nurses give women symptomatic relief for musculoskeletal pain resulting from carrying heavy loads. We posit that their perceptions are derived from customary neglect of work-related health and non-communicable diseases, cultural interpretations of womanhood, limited access to relevant information, and limited interactions between health and energy sector professionals. We conclude that culturally and gender-sensitive awareness programmes are needed for local-level health professionals to effectively address health effects of biomass collection and use. This paper provides new insights into overlooked differences between globally-driven initiatives to address health effects of biomass use and local perceptions.
Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu19 citations 19 popularity Top 10% influence Top 10% impulse Average Powered by BIP!
more_vert Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2013 NetherlandsPublisher:Elsevier BV Authors: Harold J. Annegarn; Margaret Njirambo Matinga; Joy S. Clancy;pmid: 24161104
Policymakers at global level recognise that household biomass use in developing countries has significant health consequences. However, it is unclear how local-level health professionals perceive and respond to such health effects. This paper which is derived from the findings of a larger study on perceptions and responses to the harmful health effects of carrying heavy firewood loads and to smoke from cooking fires is based on a study conducted in South Africa among managers of health programmes and community nurses of Qaukeni and Mhlontlo municipalities in rural Eastern Cape. Interviews and participant observations were conducted in 2009 using ethnographic grounded theory approaches. In addition to a 10-month period of ethnographic fieldwork, ten programme managers and nurses in two villages were interviewed about health patterns in the villages that they serve, their perceptions of, and responses to the health effects of carrying heavy firewood loads, and inhalation of smoke from wood and dung cooking fires, their professional qualifications and experience, their own household energy use; and observations made as they served clinic clients. Results show that these programme managers and nurses perceive the health effects of carrying heavy loads of firewood and of cooking smoke as minor. Sometimes, nurses give women symptomatic relief for musculoskeletal pain resulting from carrying heavy loads. We posit that their perceptions are derived from customary neglect of work-related health and non-communicable diseases, cultural interpretations of womanhood, limited access to relevant information, and limited interactions between health and energy sector professionals. We conclude that culturally and gender-sensitive awareness programmes are needed for local-level health professionals to effectively address health effects of biomass collection and use. This paper provides new insights into overlooked differences between globally-driven initiatives to address health effects of biomass use and local perceptions.
Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu19 citations 19 popularity Top 10% influence Top 10% impulse Average Powered by BIP!
more_vert Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Wiley Authors: Van Strydonck, D.A.C.; Timmerman, M.F.; van der Velden, U.; van der Weijden, G.A.;AbstractBackground: Chlorhexidine (CHX) 0.2% solution is still “the leading oral antiseptic” for controlling gingivitis. Side effects, however, limit the acceptability to users and the long‐term employment of a 0.2% CHX antiseptic in preventive dentistry. This stimulated the development of new formulations. The aim of the present study was to assess the effect on plaque inhibition and taste perception of two commercially available mouthrinses (0.12% CHX non‐alcohol base with 0.05% cetyl pyridinium chloride (Cpc) versus 0.2% CHX alcohol base).Methods: The study was designed as a single‐blind, randomized two group parallel experiment, to compare two different commercially available mouthrinses, during a 3‐day plaque accumulation model. Forty healthy volunteers were enrolled in the study and received a thorough dental prophylaxis at the beginning of the test period. Over a 72‐h experimental non‐brushing period, during which subjects abstained from all forms of mechanical oral hygiene, one group (test) used a 15 ml alcohol free 0.12% CHX (=18 mg) mouthrinse on a Cpc base (Perioaid®, CHX⊕Cpc), twice daily for 30 s. The other group (control) used a 10 ml 0.2% CHX (=20 mg) mouthrinse on an 11.8% ethanol alcohol base (Corsodyl®, CHX⊕Alc), twice daily for 60 s. After 72 h of plaque formation, the amount of plaque was evaluated. By the use of visual analogue scale, the subjects were asked for their appreciation of the taste of the mouthrinse they had used.Results: The mean plaque index for the CHX⊕Cpc group was 0.97 and for the CHX⊕Alc group 0.78. After 72 h of non‐brushing, there was no significant difference in plaque accumulation between the two groups. The answers to the questions (taste perception and after‐taste) showed a statistically significant difference between the two groups. The mean visual analogue scale (VAS) scores for taste appreciation on a scale from very bad to very good taste (0–10) were 5.92 for the CHX⊕Cpc group and 4.10 for the CHX⊕Alc group (p=0.02). The mean visual analogue scale (VAS) scores for the after‐taste on a scale from very short to very long (0–10) were 7.24 for the CHX⊕Cpc group and 5.38 for the CHX⊕Alc group.Conclusions: Within the limitations of the present study design, it can be concluded that rinsing with a 0.12% CHX mouthrinse on a non‐alcohol base with 0.05% Cpc (Perio‐Aid®) is not significantly different from rinsing with a 0.2% CHX mouthrinse on an alcohol base (Corsodyl®). It appears that the subjects appreciated the taste of the non‐alcohol CHX solution better but the after‐taste of the rinse remained longer in the mouth.
Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu91 citations 91 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Wiley Authors: Van Strydonck, D.A.C.; Timmerman, M.F.; van der Velden, U.; van der Weijden, G.A.;AbstractBackground: Chlorhexidine (CHX) 0.2% solution is still “the leading oral antiseptic” for controlling gingivitis. Side effects, however, limit the acceptability to users and the long‐term employment of a 0.2% CHX antiseptic in preventive dentistry. This stimulated the development of new formulations. The aim of the present study was to assess the effect on plaque inhibition and taste perception of two commercially available mouthrinses (0.12% CHX non‐alcohol base with 0.05% cetyl pyridinium chloride (Cpc) versus 0.2% CHX alcohol base).Methods: The study was designed as a single‐blind, randomized two group parallel experiment, to compare two different commercially available mouthrinses, during a 3‐day plaque accumulation model. Forty healthy volunteers were enrolled in the study and received a thorough dental prophylaxis at the beginning of the test period. Over a 72‐h experimental non‐brushing period, during which subjects abstained from all forms of mechanical oral hygiene, one group (test) used a 15 ml alcohol free 0.12% CHX (=18 mg) mouthrinse on a Cpc base (Perioaid®, CHX⊕Cpc), twice daily for 30 s. The other group (control) used a 10 ml 0.2% CHX (=20 mg) mouthrinse on an 11.8% ethanol alcohol base (Corsodyl®, CHX⊕Alc), twice daily for 60 s. After 72 h of plaque formation, the amount of plaque was evaluated. By the use of visual analogue scale, the subjects were asked for their appreciation of the taste of the mouthrinse they had used.Results: The mean plaque index for the CHX⊕Cpc group was 0.97 and for the CHX⊕Alc group 0.78. After 72 h of non‐brushing, there was no significant difference in plaque accumulation between the two groups. The answers to the questions (taste perception and after‐taste) showed a statistically significant difference between the two groups. The mean visual analogue scale (VAS) scores for taste appreciation on a scale from very bad to very good taste (0–10) were 5.92 for the CHX⊕Cpc group and 4.10 for the CHX⊕Alc group (p=0.02). The mean visual analogue scale (VAS) scores for the after‐taste on a scale from very short to very long (0–10) were 7.24 for the CHX⊕Cpc group and 5.38 for the CHX⊕Alc group.Conclusions: Within the limitations of the present study design, it can be concluded that rinsing with a 0.12% CHX mouthrinse on a non‐alcohol base with 0.05% Cpc (Perio‐Aid®) is not significantly different from rinsing with a 0.2% CHX mouthrinse on an alcohol base (Corsodyl®). It appears that the subjects appreciated the taste of the non‐alcohol CHX solution better but the after‐taste of the rinse remained longer in the mouth.
Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu91 citations 91 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2015 United KingdomPublisher:SAGE Publications Authors: van Amsterdam, J.; Nutt, D.; Phillips, L.D.; van den Brink, W.;pmid: 25922421
Background: The present paper describes the results of a rating study performed by a group of European Union (EU) drug experts using the multi-criteria decision analysis model for evaluating drug harms. Methods: Forty drug experts from throughout the EU scored 20 drugs on 16 harm criteria. The expert group also assessed criteria weights that would apply, on average, across the EU. Weighted averages of the scores provided a single, overall weighted harm score (range: 0–100) for each drug. Results: Alcohol, heroin and crack emerged as the most harmful drugs (overall weighted harm score 72, 55 and 50, respectively). The remaining drugs had an overall weighted harm score of 38 or less, making them much less harmful than alcohol. The overall weighted harm scores of the EU experts correlated well with those previously given by the UK panel. Conclusion: The outcome of this study shows that the previous national rankings based on the relative harms of different drugs are endorsed throughout the EU. The results indicates that EU and national drug policy measures should focus on drugs with the highest overall harm, including alcohol and tobacco, whereas drugs such as cannabis and ecstasy should be given lower priority including a lower legal classification.
Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu168 citations 168 popularity Top 1% influence Top 1% impulse Top 1% Powered by BIP!
more_vert Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2015 United KingdomPublisher:SAGE Publications Authors: van Amsterdam, J.; Nutt, D.; Phillips, L.D.; van den Brink, W.;pmid: 25922421
Background: The present paper describes the results of a rating study performed by a group of European Union (EU) drug experts using the multi-criteria decision analysis model for evaluating drug harms. Methods: Forty drug experts from throughout the EU scored 20 drugs on 16 harm criteria. The expert group also assessed criteria weights that would apply, on average, across the EU. Weighted averages of the scores provided a single, overall weighted harm score (range: 0–100) for each drug. Results: Alcohol, heroin and crack emerged as the most harmful drugs (overall weighted harm score 72, 55 and 50, respectively). The remaining drugs had an overall weighted harm score of 38 or less, making them much less harmful than alcohol. The overall weighted harm scores of the EU experts correlated well with those previously given by the UK panel. Conclusion: The outcome of this study shows that the previous national rankings based on the relative harms of different drugs are endorsed throughout the EU. The results indicates that EU and national drug policy measures should focus on drugs with the highest overall harm, including alcohol and tobacco, whereas drugs such as cannabis and ecstasy should be given lower priority including a lower legal classification.
Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu168 citations 168 popularity Top 1% influence Top 1% impulse Top 1% Powered by BIP!
more_vert Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2014 NetherlandsPublisher:Wiley Authors: Raja A. S. Mukherjee; Sheila Hollins; Leopold M. G. Curfs; Elizabeth Wray;doi: 10.1111/cch.12187
pmid: 25251603
AbstractIntroductionFoetal alcohol spectrum disorders (FASD) are a set of preventable conditions where the foetus is exposed to alcohol in utero and as a result suffers adverse consequences. To develop a public health strategy related to FASD, it is important to first establish what is known by the public about this condition. This study aimed to assess the current level of knowledge about FASD in the UK general population.MethodsA mixed methodology study was conducted using a 17‐item questionnaire and focus group sessions. Four focus groups were held with an average of 10 people in each group. Semi‐structured questions and thematic analysis of interviews alongside quantitative analysis of the questionnaire data was completed. The research was approved by an National Health service (NHS) research ethical committee.ResultsA total of 674 people responded to the questionnaire and a majority (86.7%) had heard about FASD, with most receiving their information from the media (26.2%) or from their work (27.7%). Four broad themes emerged. Overall these were: a general lack of knowledge about the subject; information about the subject needed to be personally relevant; there was a need for further education; and there was a lack of clarity in the current guidance on alcohol use in pregnancy.Discussion and conclusionsCurrently there appears to be a superficial level of knowledge about FASD in the UK general public. More detailed work in subgroups, such as young women, to identify their specific needs may be necessary before targeted public health and educational interventions can be developed to meet the needs of the general public.
Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu21 citations 21 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2014 NetherlandsPublisher:Wiley Authors: Raja A. S. Mukherjee; Sheila Hollins; Leopold M. G. Curfs; Elizabeth Wray;doi: 10.1111/cch.12187
pmid: 25251603
AbstractIntroductionFoetal alcohol spectrum disorders (FASD) are a set of preventable conditions where the foetus is exposed to alcohol in utero and as a result suffers adverse consequences. To develop a public health strategy related to FASD, it is important to first establish what is known by the public about this condition. This study aimed to assess the current level of knowledge about FASD in the UK general population.MethodsA mixed methodology study was conducted using a 17‐item questionnaire and focus group sessions. Four focus groups were held with an average of 10 people in each group. Semi‐structured questions and thematic analysis of interviews alongside quantitative analysis of the questionnaire data was completed. The research was approved by an National Health service (NHS) research ethical committee.ResultsA total of 674 people responded to the questionnaire and a majority (86.7%) had heard about FASD, with most receiving their information from the media (26.2%) or from their work (27.7%). Four broad themes emerged. Overall these were: a general lack of knowledge about the subject; information about the subject needed to be personally relevant; there was a need for further education; and there was a lack of clarity in the current guidance on alcohol use in pregnancy.Discussion and conclusionsCurrently there appears to be a superficial level of knowledge about FASD in the UK general public. More detailed work in subgroups, such as young women, to identify their specific needs may be necessary before targeted public health and educational interventions can be developed to meet the needs of the general public.
Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu21 citations 21 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2016 NetherlandsPublisher:Elsevier BV Authors: W.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; +4 AuthorsW.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; Michel M. Joosten; Renger F. Witkamp; Ilse C. Schrieks; Ilse C. Schrieks;Alcohol is often consumed to reduce tension and improve mood when exposed to stressful situations. Previous studies showed that moderate alcohol consumption may reduce stress when alcohol is consumed prior to a stressor, but data on the effect of alcohol consumption after a mental stressor is limited. Therefore, our objective was to study whether moderate alcohol consumption immediately after a mental stressor attenuates the stress response. Twenty-four healthy men (age 21-40 y, BMI 18-27 kg/m2) participated in a placebo-controlled trial. They randomly consumed 2 cans (660 mL, ∼26 g alcohol) of beer or alcohol-free beer immediately after a mental stressor (Stroop task and Trier Social Stress Test). Physiological and immunological stress response was measured by monitoring heart rate and repeated measures of the hypothalamic-pituitary-adrenal axis (HPA-axis), white blood cells and a set of cytokines. After a mental stressor, cortisol and adrenocorticotropic hormone (ACTH) concentrations were 100% and 176% more reduced at 60 min (P = 0.012 and P = 0.001, respectively) and 92% and 60% more reduced at 90 min (P < 0.001 and P = 0.056, respectively) after beer consumption as compared to alcohol-free beer consumption. Heart rate and dehydroepiandrosterone (DHEA) were not influenced by alcohol consumption. Plasma IL-8 concentrations remained lower during the stress recovery period after beer consumption than after alcohol-free beer consumption (P < 0.001). In conclusion, consumption of a moderate dose of alcohol after a mental stressor may facilitate recovery of the endocrine stress response as reflected by decreasing plasma ACTH and cortisol.
Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu15 citations 15 popularity Top 10% influence Average impulse Average Powered by BIP!
more_vert Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2016 NetherlandsPublisher:Elsevier BV Authors: W.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; +4 AuthorsW.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; Michel M. Joosten; Renger F. Witkamp; Ilse C. Schrieks; Ilse C. Schrieks;Alcohol is often consumed to reduce tension and improve mood when exposed to stressful situations. Previous studies showed that moderate alcohol consumption may reduce stress when alcohol is consumed prior to a stressor, but data on the effect of alcohol consumption after a mental stressor is limited. Therefore, our objective was to study whether moderate alcohol consumption immediately after a mental stressor attenuates the stress response. Twenty-four healthy men (age 21-40 y, BMI 18-27 kg/m2) participated in a placebo-controlled trial. They randomly consumed 2 cans (660 mL, ∼26 g alcohol) of beer or alcohol-free beer immediately after a mental stressor (Stroop task and Trier Social Stress Test). Physiological and immunological stress response was measured by monitoring heart rate and repeated measures of the hypothalamic-pituitary-adrenal axis (HPA-axis), white blood cells and a set of cytokines. After a mental stressor, cortisol and adrenocorticotropic hormone (ACTH) concentrations were 100% and 176% more reduced at 60 min (P = 0.012 and P = 0.001, respectively) and 92% and 60% more reduced at 90 min (P < 0.001 and P = 0.056, respectively) after beer consumption as compared to alcohol-free beer consumption. Heart rate and dehydroepiandrosterone (DHEA) were not influenced by alcohol consumption. Plasma IL-8 concentrations remained lower during the stress recovery period after beer consumption than after alcohol-free beer consumption (P < 0.001). In conclusion, consumption of a moderate dose of alcohol after a mental stressor may facilitate recovery of the endocrine stress response as reflected by decreasing plasma ACTH and cortisol.
Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu15 citations 15 popularity Top 10% influence Average impulse Average Powered by BIP!
more_vert Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Conference object , Article 2020 ItalyPublisher:IEEE Funded by:EC | eDREAMEC| eDREAMAuthors: Carere F.; Bragatto T.; Santori F.;handle: 11573/1486129
During an extraordinary event, like the COVID19 pandemic, very rapid changes in consumption profiles and customers behaviors were recorded. This paper investigates the impact of the lockdown on load and production in the distribution system of Terni. From a DSO point of view, no relevant issues were encountered to be faced. The distributed power generation from renewable resources did not affect relevant issues, maintaining the typical annual generation profiles. A domestic consumption increase was replaced by more relevant decrease of industrial processes and commercial activities absorptions. More than 25,000 domestic users increased their consumptions in April 2020 and the overall consumption of domestic customers in March was 1,05 times higher than the 2015 respectively consumption. The power flows at primary substations reveal a relevant electric demand reduction for each point of connection with the high voltage transmission system; especially bar 1 and 2 of the most relevant Terni primary substation, recorded a 15.3% decrease with respect to March 2019, and a 24.25% decrease with respect to April 2019.
Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu13 citations 13 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Conference object , Article 2020 ItalyPublisher:IEEE Funded by:EC | eDREAMEC| eDREAMAuthors: Carere F.; Bragatto T.; Santori F.;handle: 11573/1486129
During an extraordinary event, like the COVID19 pandemic, very rapid changes in consumption profiles and customers behaviors were recorded. This paper investigates the impact of the lockdown on load and production in the distribution system of Terni. From a DSO point of view, no relevant issues were encountered to be faced. The distributed power generation from renewable resources did not affect relevant issues, maintaining the typical annual generation profiles. A domestic consumption increase was replaced by more relevant decrease of industrial processes and commercial activities absorptions. More than 25,000 domestic users increased their consumptions in April 2020 and the overall consumption of domestic customers in March was 1,05 times higher than the 2015 respectively consumption. The power flows at primary substations reveal a relevant electric demand reduction for each point of connection with the high voltage transmission system; especially bar 1 and 2 of the most relevant Terni primary substation, recorded a 15.3% decrease with respect to March 2019, and a 24.25% decrease with respect to April 2019.
Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu13 citations 13 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 NetherlandsPublisher:Elsevier BV Carolien Thush; J. F. van den Bosch; Joke Opdenacker; Frans J. M. Feron; N. Theunissen; P. van Empelen; Mirjam Moerbeek; Reinout W. Wiers; Reinout W. Wiers;pmid: 16928395
This study investigated the effectiveness of a targeted intervention program aimed at at-risk adolescents in a randomized clinical trial design (N=107). This program combined intervention methods which have been proven effective in reducing drinking in young adults, such as an expectancy challenge, cognitive behavioral skill training and brief motivational feedback. Additionally, this intervention contained the new element of discussing biological, cognitive and social risk factors for developing alcohol problems. We investigated whether this seven session program was successful in changing cognitive determinants of drinking behavior and consequently in moderating alcohol use and the development of alcohol-related problems in at-risk adolescents. The intervention was effective in changing several of the targeted cognitive determinants. However, despite the changes in these cognitive determinants of drinking, the experimental group did not show a significant difference in decrease of drinking at posttest compared with the control group. The results did not yield support for any differential long term effects of the intervention. We concluded that although the present intervention successfully changed important cognitive determinants of drinking more is needed to change subsequent drinking behavior in at-risk adolescents.
Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu25 citations 25 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 NetherlandsPublisher:Elsevier BV Carolien Thush; J. F. van den Bosch; Joke Opdenacker; Frans J. M. Feron; N. Theunissen; P. van Empelen; Mirjam Moerbeek; Reinout W. Wiers; Reinout W. Wiers;pmid: 16928395
This study investigated the effectiveness of a targeted intervention program aimed at at-risk adolescents in a randomized clinical trial design (N=107). This program combined intervention methods which have been proven effective in reducing drinking in young adults, such as an expectancy challenge, cognitive behavioral skill training and brief motivational feedback. Additionally, this intervention contained the new element of discussing biological, cognitive and social risk factors for developing alcohol problems. We investigated whether this seven session program was successful in changing cognitive determinants of drinking behavior and consequently in moderating alcohol use and the development of alcohol-related problems in at-risk adolescents. The intervention was effective in changing several of the targeted cognitive determinants. However, despite the changes in these cognitive determinants of drinking, the experimental group did not show a significant difference in decrease of drinking at posttest compared with the control group. The results did not yield support for any differential long term effects of the intervention. We concluded that although the present intervention successfully changed important cognitive determinants of drinking more is needed to change subsequent drinking behavior in at-risk adolescents.
Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu25 citations 25 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 DenmarkPublisher:Springer Science and Business Media LLC Fatouros, Dimitrios G.; Deen, Roshan; Arleth, Lise; Bergenstahl, Bjørn; Nielsen, Flemming Seier; Pedersen, Jan Skov; Müllertz, Anette;pmid: 17458683
To investigate the structural development of the colloid phases generated during lipolysis of a lipid-based formulation in an in vitro lipolysis model, which simulates digestion in the small intestine.Small-Angle X-Ray scattering (SAXS) coupled with the in vitro lipolysis model which accurately reproduces the solubilizing environment in the gastrointestinal tract and simulates gastrointestinal lipid digestion through the use of bile and pancreatic extracts. The combined method was used to follow the intermediate digestion products of a self nano emulsified drug delivery system (SNEDDS) under fasted conditions. SNEDDS is developed to facilitate the uptake of poorly soluble drugs.The data revealed that a lamellar phase forms immediately after initiation of lipolysis, whereas a hexagonal phase is formed after 60 min. The change of the relative amounts of these phases clearly demonstrates that lipolysis is a dynamic process. The formation of these phases is driven by the lipase which continuously hydrolyzes triglycerides from the oil-cores of the nanoemulsion droplets into mono- and diglycerides and fatty acids. We propose that this change of the over-all composition of the intestinal fluid with increased fraction of hydrolyzed nanoemulsion induces a change in the composition and effective critical packing parameter of the amphiphilic molecules, which determines the phase behavior of the system. Control experiments (only the digestion medium) or the surfactant (Cremophor RH 40) revealed the formation of a lamellar phase demonstrating that the hexagonal phase is due to the hydrolysis of the SNEDDS formulation.The current results demonstrate that SAXS measurements combined with the in vitro dynamic lipolysis model may be used to elucidate the processes encountered during the digestion of lipid-based formulations of poorly soluble drugs for oral drug delivery. Thus the combined methods may act as an efficient screening tool.
PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11095-007-9304-6&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu117 citations 117 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 DenmarkPublisher:Springer Science and Business Media LLC Fatouros, Dimitrios G.; Deen, Roshan; Arleth, Lise; Bergenstahl, Bjørn; Nielsen, Flemming Seier; Pedersen, Jan Skov; Müllertz, Anette;pmid: 17458683
To investigate the structural development of the colloid phases generated during lipolysis of a lipid-based formulation in an in vitro lipolysis model, which simulates digestion in the small intestine.Small-Angle X-Ray scattering (SAXS) coupled with the in vitro lipolysis model which accurately reproduces the solubilizing environment in the gastrointestinal tract and simulates gastrointestinal lipid digestion through the use of bile and pancreatic extracts. The combined method was used to follow the intermediate digestion products of a self nano emulsified drug delivery system (SNEDDS) under fasted conditions. SNEDDS is developed to facilitate the uptake of poorly soluble drugs.The data revealed that a lamellar phase forms immediately after initiation of lipolysis, whereas a hexagonal phase is formed after 60 min. The change of the relative amounts of these phases clearly demonstrates that lipolysis is a dynamic process. The formation of these phases is driven by the lipase which continuously hydrolyzes triglycerides from the oil-cores of the nanoemulsion droplets into mono- and diglycerides and fatty acids. We propose that this change of the over-all composition of the intestinal fluid with increased fraction of hydrolyzed nanoemulsion induces a change in the composition and effective critical packing parameter of the amphiphilic molecules, which determines the phase behavior of the system. Control experiments (only the digestion medium) or the surfactant (Cremophor RH 40) revealed the formation of a lamellar phase demonstrating that the hexagonal phase is due to the hydrolysis of the SNEDDS formulation.The current results demonstrate that SAXS measurements combined with the in vitro dynamic lipolysis model may be used to elucidate the processes encountered during the digestion of lipid-based formulations of poorly soluble drugs for oral drug delivery. Thus the combined methods may act as an efficient screening tool.
PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11095-007-9304-6&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu117 citations 117 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Elsevier BV Authors: Stoelinga, P.J.W.;t dontogenic keratocysts (OKCs) are known for their ropensity to recur. The rate of recurrence is probaly largely depending on the mode of treatment used. nfortunately, there are only a few reliable studies vailable from which meaningful conclusions can be rawn with regard to the best possible treatment trategy. The main drawback of most studies is the etrospective nature of the study, the variable folow-up time, the lack of information about the perentage of patients available for follow-up, and the ack of details about the actual surgery. Many papers re written by pathologists who obviously are deending on the written and often incomplete notes of urgeons, hence the link with the clinical parameters s often based on less than optimal information. It is he aim of this article to present a rational treatment rotocol based on clinical and histologic studies.
Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.joms.2005.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu132 citations 132 popularity Top 10% influence Top 1% impulse Average Powered by BIP!
more_vert Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.joms.2005.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Elsevier BV Authors: Stoelinga, P.J.W.;t dontogenic keratocysts (OKCs) are known for their ropensity to recur. The rate of recurrence is probaly largely depending on the mode of treatment used. nfortunately, there are only a few reliable studies vailable from which meaningful conclusions can be rawn with regard to the best possible treatment trategy. The main drawback of most studies is the etrospective nature of the study, the variable folow-up time, the lack of information about the perentage of patients available for follow-up, and the ack of details about the actual surgery. Many papers re written by pathologists who obviously are deending on the written and often incomplete notes of urgeons, hence the link with the clinical parameters s often based on less than optimal information. It is he aim of this article to present a rational treatment rotocol based on clinical and histologic studies.
Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.joms.2005.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu132 citations 132 popularity Top 10% influence Top 1% impulse Average Powered by BIP!
more_vert Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Article , Journal 2012 PeruPublisher:Elsevier BV Berrang-Ford, L.; Dingle, K.; Ford, J.D.; Lee, C.; Lwasa, S.; Namanya, D.B.; Henderson, J.; Llanos Cuentas, Elmer Alejandro; Cárcamo Cavagnaro, César Paul Eugenio; Edge, V.;The potential impacts of climate change on human health in sub-Saharan Africa are wide-ranging, complex, and largely adverse. The region's Indigenous peoples are considered to be at heightened risk given their relatively poor health outcomes, marginal social status, and resource-based livelihoods; however, little attention has been given to these most vulnerable of the vulnerable. This paper contributes to addressing this gap by taking a bottom-up approach to assessing health vulnerabilities to climate change in two Batwa Pygmy communities in rural Uganda. Rapid Rural Appraisal and PhotoVoice field methods complemented by qualitative data analysis were used to identify key climate-sensitive, community-identified health outcomes, describe determinants of sensitivity at multiple scales, and characterize adaptive capacity of Batwa health systems. The findings stress the importance of human drivers of vulnerability and adaptive capacity and the need to address social determinants of health in order to reduce the potential disease burden of climate change.
Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu84 citations 84 popularity Top 1% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2012 PeruPublisher:Elsevier BV Berrang-Ford, L.; Dingle, K.; Ford, J.D.; Lee, C.; Lwasa, S.; Namanya, D.B.; Henderson, J.; Llanos Cuentas, Elmer Alejandro; Cárcamo Cavagnaro, César Paul Eugenio; Edge, V.;The potential impacts of climate change on human health in sub-Saharan Africa are wide-ranging, complex, and largely adverse. The region's Indigenous peoples are considered to be at heightened risk given their relatively poor health outcomes, marginal social status, and resource-based livelihoods; however, little attention has been given to these most vulnerable of the vulnerable. This paper contributes to addressing this gap by taking a bottom-up approach to assessing health vulnerabilities to climate change in two Batwa Pygmy communities in rural Uganda. Rapid Rural Appraisal and PhotoVoice field methods complemented by qualitative data analysis were used to identify key climate-sensitive, community-identified health outcomes, describe determinants of sensitivity at multiple scales, and characterize adaptive capacity of Batwa health systems. The findings stress the importance of human drivers of vulnerability and adaptive capacity and the need to address social determinants of health in order to reduce the potential disease burden of climate change.
Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu84 citations 84 popularity Top 1% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Repositorio Instituc... arrow_drop_down Social Science & MedicineArticle . 2012 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2012.04.016&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2013 NetherlandsPublisher:Elsevier BV Authors: Harold J. Annegarn; Margaret Njirambo Matinga; Joy S. Clancy;pmid: 24161104
Policymakers at global level recognise that household biomass use in developing countries has significant health consequences. However, it is unclear how local-level health professionals perceive and respond to such health effects. This paper which is derived from the findings of a larger study on perceptions and responses to the harmful health effects of carrying heavy firewood loads and to smoke from cooking fires is based on a study conducted in South Africa among managers of health programmes and community nurses of Qaukeni and Mhlontlo municipalities in rural Eastern Cape. Interviews and participant observations were conducted in 2009 using ethnographic grounded theory approaches. In addition to a 10-month period of ethnographic fieldwork, ten programme managers and nurses in two villages were interviewed about health patterns in the villages that they serve, their perceptions of, and responses to the health effects of carrying heavy firewood loads, and inhalation of smoke from wood and dung cooking fires, their professional qualifications and experience, their own household energy use; and observations made as they served clinic clients. Results show that these programme managers and nurses perceive the health effects of carrying heavy loads of firewood and of cooking smoke as minor. Sometimes, nurses give women symptomatic relief for musculoskeletal pain resulting from carrying heavy loads. We posit that their perceptions are derived from customary neglect of work-related health and non-communicable diseases, cultural interpretations of womanhood, limited access to relevant information, and limited interactions between health and energy sector professionals. We conclude that culturally and gender-sensitive awareness programmes are needed for local-level health professionals to effectively address health effects of biomass collection and use. This paper provides new insights into overlooked differences between globally-driven initiatives to address health effects of biomass use and local perceptions.
Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu19 citations 19 popularity Top 10% influence Top 10% impulse Average Powered by BIP!
more_vert Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2013 NetherlandsPublisher:Elsevier BV Authors: Harold J. Annegarn; Margaret Njirambo Matinga; Joy S. Clancy;pmid: 24161104
Policymakers at global level recognise that household biomass use in developing countries has significant health consequences. However, it is unclear how local-level health professionals perceive and respond to such health effects. This paper which is derived from the findings of a larger study on perceptions and responses to the harmful health effects of carrying heavy firewood loads and to smoke from cooking fires is based on a study conducted in South Africa among managers of health programmes and community nurses of Qaukeni and Mhlontlo municipalities in rural Eastern Cape. Interviews and participant observations were conducted in 2009 using ethnographic grounded theory approaches. In addition to a 10-month period of ethnographic fieldwork, ten programme managers and nurses in two villages were interviewed about health patterns in the villages that they serve, their perceptions of, and responses to the health effects of carrying heavy firewood loads, and inhalation of smoke from wood and dung cooking fires, their professional qualifications and experience, their own household energy use; and observations made as they served clinic clients. Results show that these programme managers and nurses perceive the health effects of carrying heavy loads of firewood and of cooking smoke as minor. Sometimes, nurses give women symptomatic relief for musculoskeletal pain resulting from carrying heavy loads. We posit that their perceptions are derived from customary neglect of work-related health and non-communicable diseases, cultural interpretations of womanhood, limited access to relevant information, and limited interactions between health and energy sector professionals. We conclude that culturally and gender-sensitive awareness programmes are needed for local-level health professionals to effectively address health effects of biomass collection and use. This paper provides new insights into overlooked differences between globally-driven initiatives to address health effects of biomass use and local perceptions.
Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu19 citations 19 popularity Top 10% influence Top 10% impulse Average Powered by BIP!
more_vert Social Science & Med... arrow_drop_down Social Science & MedicineArticle . 2013 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.socscimed.2013.08.015&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Wiley Authors: Van Strydonck, D.A.C.; Timmerman, M.F.; van der Velden, U.; van der Weijden, G.A.;AbstractBackground: Chlorhexidine (CHX) 0.2% solution is still “the leading oral antiseptic” for controlling gingivitis. Side effects, however, limit the acceptability to users and the long‐term employment of a 0.2% CHX antiseptic in preventive dentistry. This stimulated the development of new formulations. The aim of the present study was to assess the effect on plaque inhibition and taste perception of two commercially available mouthrinses (0.12% CHX non‐alcohol base with 0.05% cetyl pyridinium chloride (Cpc) versus 0.2% CHX alcohol base).Methods: The study was designed as a single‐blind, randomized two group parallel experiment, to compare two different commercially available mouthrinses, during a 3‐day plaque accumulation model. Forty healthy volunteers were enrolled in the study and received a thorough dental prophylaxis at the beginning of the test period. Over a 72‐h experimental non‐brushing period, during which subjects abstained from all forms of mechanical oral hygiene, one group (test) used a 15 ml alcohol free 0.12% CHX (=18 mg) mouthrinse on a Cpc base (Perioaid®, CHX⊕Cpc), twice daily for 30 s. The other group (control) used a 10 ml 0.2% CHX (=20 mg) mouthrinse on an 11.8% ethanol alcohol base (Corsodyl®, CHX⊕Alc), twice daily for 60 s. After 72 h of plaque formation, the amount of plaque was evaluated. By the use of visual analogue scale, the subjects were asked for their appreciation of the taste of the mouthrinse they had used.Results: The mean plaque index for the CHX⊕Cpc group was 0.97 and for the CHX⊕Alc group 0.78. After 72 h of non‐brushing, there was no significant difference in plaque accumulation between the two groups. The answers to the questions (taste perception and after‐taste) showed a statistically significant difference between the two groups. The mean visual analogue scale (VAS) scores for taste appreciation on a scale from very bad to very good taste (0–10) were 5.92 for the CHX⊕Cpc group and 4.10 for the CHX⊕Alc group (p=0.02). The mean visual analogue scale (VAS) scores for the after‐taste on a scale from very short to very long (0–10) were 7.24 for the CHX⊕Cpc group and 5.38 for the CHX⊕Alc group.Conclusions: Within the limitations of the present study design, it can be concluded that rinsing with a 0.12% CHX mouthrinse on a non‐alcohol base with 0.05% Cpc (Perio‐Aid®) is not significantly different from rinsing with a 0.2% CHX mouthrinse on an alcohol base (Corsodyl®). It appears that the subjects appreciated the taste of the non‐alcohol CHX solution better but the after‐taste of the rinse remained longer in the mouth.
Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu91 citations 91 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Wiley Authors: Van Strydonck, D.A.C.; Timmerman, M.F.; van der Velden, U.; van der Weijden, G.A.;AbstractBackground: Chlorhexidine (CHX) 0.2% solution is still “the leading oral antiseptic” for controlling gingivitis. Side effects, however, limit the acceptability to users and the long‐term employment of a 0.2% CHX antiseptic in preventive dentistry. This stimulated the development of new formulations. The aim of the present study was to assess the effect on plaque inhibition and taste perception of two commercially available mouthrinses (0.12% CHX non‐alcohol base with 0.05% cetyl pyridinium chloride (Cpc) versus 0.2% CHX alcohol base).Methods: The study was designed as a single‐blind, randomized two group parallel experiment, to compare two different commercially available mouthrinses, during a 3‐day plaque accumulation model. Forty healthy volunteers were enrolled in the study and received a thorough dental prophylaxis at the beginning of the test period. Over a 72‐h experimental non‐brushing period, during which subjects abstained from all forms of mechanical oral hygiene, one group (test) used a 15 ml alcohol free 0.12% CHX (=18 mg) mouthrinse on a Cpc base (Perioaid®, CHX⊕Cpc), twice daily for 30 s. The other group (control) used a 10 ml 0.2% CHX (=20 mg) mouthrinse on an 11.8% ethanol alcohol base (Corsodyl®, CHX⊕Alc), twice daily for 60 s. After 72 h of plaque formation, the amount of plaque was evaluated. By the use of visual analogue scale, the subjects were asked for their appreciation of the taste of the mouthrinse they had used.Results: The mean plaque index for the CHX⊕Cpc group was 0.97 and for the CHX⊕Alc group 0.78. After 72 h of non‐brushing, there was no significant difference in plaque accumulation between the two groups. The answers to the questions (taste perception and after‐taste) showed a statistically significant difference between the two groups. The mean visual analogue scale (VAS) scores for taste appreciation on a scale from very bad to very good taste (0–10) were 5.92 for the CHX⊕Cpc group and 4.10 for the CHX⊕Alc group (p=0.02). The mean visual analogue scale (VAS) scores for the after‐taste on a scale from very short to very long (0–10) were 7.24 for the CHX⊕Cpc group and 5.38 for the CHX⊕Alc group.Conclusions: Within the limitations of the present study design, it can be concluded that rinsing with a 0.12% CHX mouthrinse on a non‐alcohol base with 0.05% Cpc (Perio‐Aid®) is not significantly different from rinsing with a 0.2% CHX mouthrinse on an alcohol base (Corsodyl®). It appears that the subjects appreciated the taste of the non‐alcohol CHX solution better but the after‐taste of the rinse remained longer in the mouth.
Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu91 citations 91 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Journal Of Clinical ... arrow_drop_down Journal Of Clinical PeriodontologyArticle . 2005Data sources: DANS (Data Archiving and Networked Services)Journal Of Clinical PeriodontologyArticle . 2005 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniversiteit van Amsterdam: Digital Academic Repository (UvA DARE)Article . 2005Data sources: Bielefeld Academic Search Engine (BASE)Journal Of Clinical PeriodontologyArticle . 2005Data sources: Universiteit van Amsterdam Digital Academic RepositoryJournal Of Clinical PeriodontologyArticle . 2005add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/j.1600-051x.2005.00681.x&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2015 United KingdomPublisher:SAGE Publications Authors: van Amsterdam, J.; Nutt, D.; Phillips, L.D.; van den Brink, W.;pmid: 25922421
Background: The present paper describes the results of a rating study performed by a group of European Union (EU) drug experts using the multi-criteria decision analysis model for evaluating drug harms. Methods: Forty drug experts from throughout the EU scored 20 drugs on 16 harm criteria. The expert group also assessed criteria weights that would apply, on average, across the EU. Weighted averages of the scores provided a single, overall weighted harm score (range: 0–100) for each drug. Results: Alcohol, heroin and crack emerged as the most harmful drugs (overall weighted harm score 72, 55 and 50, respectively). The remaining drugs had an overall weighted harm score of 38 or less, making them much less harmful than alcohol. The overall weighted harm scores of the EU experts correlated well with those previously given by the UK panel. Conclusion: The outcome of this study shows that the previous national rankings based on the relative harms of different drugs are endorsed throughout the EU. The results indicates that EU and national drug policy measures should focus on drugs with the highest overall harm, including alcohol and tobacco, whereas drugs such as cannabis and ecstasy should be given lower priority including a lower legal classification.
Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu168 citations 168 popularity Top 1% influence Top 1% impulse Top 1% Powered by BIP!
more_vert Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2015 United KingdomPublisher:SAGE Publications Authors: van Amsterdam, J.; Nutt, D.; Phillips, L.D.; van den Brink, W.;pmid: 25922421
Background: The present paper describes the results of a rating study performed by a group of European Union (EU) drug experts using the multi-criteria decision analysis model for evaluating drug harms. Methods: Forty drug experts from throughout the EU scored 20 drugs on 16 harm criteria. The expert group also assessed criteria weights that would apply, on average, across the EU. Weighted averages of the scores provided a single, overall weighted harm score (range: 0–100) for each drug. Results: Alcohol, heroin and crack emerged as the most harmful drugs (overall weighted harm score 72, 55 and 50, respectively). The remaining drugs had an overall weighted harm score of 38 or less, making them much less harmful than alcohol. The overall weighted harm scores of the EU experts correlated well with those previously given by the UK panel. Conclusion: The outcome of this study shows that the previous national rankings based on the relative harms of different drugs are endorsed throughout the EU. The results indicates that EU and national drug policy measures should focus on drugs with the highest overall harm, including alcohol and tobacco, whereas drugs such as cannabis and ecstasy should be given lower priority including a lower legal classification.
Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu168 citations 168 popularity Top 1% influence Top 1% impulse Top 1% Powered by BIP!
more_vert Journal of Psychopha... arrow_drop_down Journal of PsychopharmacologyArticle . 2015Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1177/0269881115581980&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2014 NetherlandsPublisher:Wiley Authors: Raja A. S. Mukherjee; Sheila Hollins; Leopold M. G. Curfs; Elizabeth Wray;doi: 10.1111/cch.12187
pmid: 25251603
AbstractIntroductionFoetal alcohol spectrum disorders (FASD) are a set of preventable conditions where the foetus is exposed to alcohol in utero and as a result suffers adverse consequences. To develop a public health strategy related to FASD, it is important to first establish what is known by the public about this condition. This study aimed to assess the current level of knowledge about FASD in the UK general population.MethodsA mixed methodology study was conducted using a 17‐item questionnaire and focus group sessions. Four focus groups were held with an average of 10 people in each group. Semi‐structured questions and thematic analysis of interviews alongside quantitative analysis of the questionnaire data was completed. The research was approved by an National Health service (NHS) research ethical committee.ResultsA total of 674 people responded to the questionnaire and a majority (86.7%) had heard about FASD, with most receiving their information from the media (26.2%) or from their work (27.7%). Four broad themes emerged. Overall these were: a general lack of knowledge about the subject; information about the subject needed to be personally relevant; there was a need for further education; and there was a lack of clarity in the current guidance on alcohol use in pregnancy.Discussion and conclusionsCurrently there appears to be a superficial level of knowledge about FASD in the UK general public. More detailed work in subgroups, such as young women, to identify their specific needs may be necessary before targeted public health and educational interventions can be developed to meet the needs of the general public.
Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu21 citations 21 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2014 NetherlandsPublisher:Wiley Authors: Raja A. S. Mukherjee; Sheila Hollins; Leopold M. G. Curfs; Elizabeth Wray;doi: 10.1111/cch.12187
pmid: 25251603
AbstractIntroductionFoetal alcohol spectrum disorders (FASD) are a set of preventable conditions where the foetus is exposed to alcohol in utero and as a result suffers adverse consequences. To develop a public health strategy related to FASD, it is important to first establish what is known by the public about this condition. This study aimed to assess the current level of knowledge about FASD in the UK general population.MethodsA mixed methodology study was conducted using a 17‐item questionnaire and focus group sessions. Four focus groups were held with an average of 10 people in each group. Semi‐structured questions and thematic analysis of interviews alongside quantitative analysis of the questionnaire data was completed. The research was approved by an National Health service (NHS) research ethical committee.ResultsA total of 674 people responded to the questionnaire and a majority (86.7%) had heard about FASD, with most receiving their information from the media (26.2%) or from their work (27.7%). Four broad themes emerged. Overall these were: a general lack of knowledge about the subject; information about the subject needed to be personally relevant; there was a need for further education; and there was a lack of clarity in the current guidance on alcohol use in pregnancy.Discussion and conclusionsCurrently there appears to be a superficial level of knowledge about FASD in the UK general public. More detailed work in subgroups, such as young women, to identify their specific needs may be necessary before targeted public health and educational interventions can be developed to meet the needs of the general public.
Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu21 citations 21 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Child Care Health an... arrow_drop_down Child Care Health and DevelopmentArticle . 2015Data sources: DANS (Data Archiving and Networked Services)Child Care Health and DevelopmentArticle . 2014 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefChild Care Health and DevelopmentArticle . 2015Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/cch.12187&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2016 NetherlandsPublisher:Elsevier BV Authors: W.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; +4 AuthorsW.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; Michel M. Joosten; Renger F. Witkamp; Ilse C. Schrieks; Ilse C. Schrieks;Alcohol is often consumed to reduce tension and improve mood when exposed to stressful situations. Previous studies showed that moderate alcohol consumption may reduce stress when alcohol is consumed prior to a stressor, but data on the effect of alcohol consumption after a mental stressor is limited. Therefore, our objective was to study whether moderate alcohol consumption immediately after a mental stressor attenuates the stress response. Twenty-four healthy men (age 21-40 y, BMI 18-27 kg/m2) participated in a placebo-controlled trial. They randomly consumed 2 cans (660 mL, ∼26 g alcohol) of beer or alcohol-free beer immediately after a mental stressor (Stroop task and Trier Social Stress Test). Physiological and immunological stress response was measured by monitoring heart rate and repeated measures of the hypothalamic-pituitary-adrenal axis (HPA-axis), white blood cells and a set of cytokines. After a mental stressor, cortisol and adrenocorticotropic hormone (ACTH) concentrations were 100% and 176% more reduced at 60 min (P = 0.012 and P = 0.001, respectively) and 92% and 60% more reduced at 90 min (P < 0.001 and P = 0.056, respectively) after beer consumption as compared to alcohol-free beer consumption. Heart rate and dehydroepiandrosterone (DHEA) were not influenced by alcohol consumption. Plasma IL-8 concentrations remained lower during the stress recovery period after beer consumption than after alcohol-free beer consumption (P < 0.001). In conclusion, consumption of a moderate dose of alcohol after a mental stressor may facilitate recovery of the endocrine stress response as reflected by decreasing plasma ACTH and cortisol.
Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu15 citations 15 popularity Top 10% influence Average impulse Average Powered by BIP!
more_vert Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2016 NetherlandsPublisher:Elsevier BV Authors: W.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; +4 AuthorsW.A.A. Klöpping-Ketelaars; Henk F. J. Hendriks; Michel M. Joosten; Michel M. Joosten; Michel M. Joosten; Renger F. Witkamp; Ilse C. Schrieks; Ilse C. Schrieks;Alcohol is often consumed to reduce tension and improve mood when exposed to stressful situations. Previous studies showed that moderate alcohol consumption may reduce stress when alcohol is consumed prior to a stressor, but data on the effect of alcohol consumption after a mental stressor is limited. Therefore, our objective was to study whether moderate alcohol consumption immediately after a mental stressor attenuates the stress response. Twenty-four healthy men (age 21-40 y, BMI 18-27 kg/m2) participated in a placebo-controlled trial. They randomly consumed 2 cans (660 mL, ∼26 g alcohol) of beer or alcohol-free beer immediately after a mental stressor (Stroop task and Trier Social Stress Test). Physiological and immunological stress response was measured by monitoring heart rate and repeated measures of the hypothalamic-pituitary-adrenal axis (HPA-axis), white blood cells and a set of cytokines. After a mental stressor, cortisol and adrenocorticotropic hormone (ACTH) concentrations were 100% and 176% more reduced at 60 min (P = 0.012 and P = 0.001, respectively) and 92% and 60% more reduced at 90 min (P < 0.001 and P = 0.056, respectively) after beer consumption as compared to alcohol-free beer consumption. Heart rate and dehydroepiandrosterone (DHEA) were not influenced by alcohol consumption. Plasma IL-8 concentrations remained lower during the stress recovery period after beer consumption than after alcohol-free beer consumption (P < 0.001). In conclusion, consumption of a moderate dose of alcohol after a mental stressor may facilitate recovery of the endocrine stress response as reflected by decreasing plasma ACTH and cortisol.
Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu15 citations 15 popularity Top 10% influence Average impulse Average Powered by BIP!
more_vert Alcohol arrow_drop_down DANS (Data Archiving and Networked Services)Article . 2016Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.alcohol.2016.10.006&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Conference object , Article 2020 ItalyPublisher:IEEE Funded by:EC | eDREAMEC| eDREAMAuthors: Carere F.; Bragatto T.; Santori F.;handle: 11573/1486129
During an extraordinary event, like the COVID19 pandemic, very rapid changes in consumption profiles and customers behaviors were recorded. This paper investigates the impact of the lockdown on load and production in the distribution system of Terni. From a DSO point of view, no relevant issues were encountered to be faced. The distributed power generation from renewable resources did not affect relevant issues, maintaining the typical annual generation profiles. A domestic consumption increase was replaced by more relevant decrease of industrial processes and commercial activities absorptions. More than 25,000 domestic users increased their consumptions in April 2020 and the overall consumption of domestic customers in March was 1,05 times higher than the 2015 respectively consumption. The power flows at primary substations reveal a relevant electric demand reduction for each point of connection with the high voltage transmission system; especially bar 1 and 2 of the most relevant Terni primary substation, recorded a 15.3% decrease with respect to March 2019, and a 24.25% decrease with respect to April 2019.
Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu13 citations 13 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Conference object , Article 2020 ItalyPublisher:IEEE Funded by:EC | eDREAMEC| eDREAMAuthors: Carere F.; Bragatto T.; Santori F.;handle: 11573/1486129
During an extraordinary event, like the COVID19 pandemic, very rapid changes in consumption profiles and customers behaviors were recorded. This paper investigates the impact of the lockdown on load and production in the distribution system of Terni. From a DSO point of view, no relevant issues were encountered to be faced. The distributed power generation from renewable resources did not affect relevant issues, maintaining the typical annual generation profiles. A domestic consumption increase was replaced by more relevant decrease of industrial processes and commercial activities absorptions. More than 25,000 domestic users increased their consumptions in April 2020 and the overall consumption of domestic customers in March was 1,05 times higher than the 2015 respectively consumption. The power flows at primary substations reveal a relevant electric demand reduction for each point of connection with the high voltage transmission system; especially bar 1 and 2 of the most relevant Terni primary substation, recorded a 15.3% decrease with respect to March 2019, and a 24.25% decrease with respect to April 2019.
Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu13 citations 13 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Archivio della ricer... arrow_drop_down http://dx.doi.org/10.23919/aei...Conference object . 2020Data sources: European Union Open Data Portaladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.23919/aeit50178.2020.9241191&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 NetherlandsPublisher:Elsevier BV Carolien Thush; J. F. van den Bosch; Joke Opdenacker; Frans J. M. Feron; N. Theunissen; P. van Empelen; Mirjam Moerbeek; Reinout W. Wiers; Reinout W. Wiers;pmid: 16928395
This study investigated the effectiveness of a targeted intervention program aimed at at-risk adolescents in a randomized clinical trial design (N=107). This program combined intervention methods which have been proven effective in reducing drinking in young adults, such as an expectancy challenge, cognitive behavioral skill training and brief motivational feedback. Additionally, this intervention contained the new element of discussing biological, cognitive and social risk factors for developing alcohol problems. We investigated whether this seven session program was successful in changing cognitive determinants of drinking behavior and consequently in moderating alcohol use and the development of alcohol-related problems in at-risk adolescents. The intervention was effective in changing several of the targeted cognitive determinants. However, despite the changes in these cognitive determinants of drinking, the experimental group did not show a significant difference in decrease of drinking at posttest compared with the control group. The results did not yield support for any differential long term effects of the intervention. We concluded that although the present intervention successfully changed important cognitive determinants of drinking more is needed to change subsequent drinking behavior in at-risk adolescents.
Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu25 citations 25 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 NetherlandsPublisher:Elsevier BV Carolien Thush; J. F. van den Bosch; Joke Opdenacker; Frans J. M. Feron; N. Theunissen; P. van Empelen; Mirjam Moerbeek; Reinout W. Wiers; Reinout W. Wiers;pmid: 16928395
This study investigated the effectiveness of a targeted intervention program aimed at at-risk adolescents in a randomized clinical trial design (N=107). This program combined intervention methods which have been proven effective in reducing drinking in young adults, such as an expectancy challenge, cognitive behavioral skill training and brief motivational feedback. Additionally, this intervention contained the new element of discussing biological, cognitive and social risk factors for developing alcohol problems. We investigated whether this seven session program was successful in changing cognitive determinants of drinking behavior and consequently in moderating alcohol use and the development of alcohol-related problems in at-risk adolescents. The intervention was effective in changing several of the targeted cognitive determinants. However, despite the changes in these cognitive determinants of drinking, the experimental group did not show a significant difference in decrease of drinking at posttest compared with the control group. The results did not yield support for any differential long term effects of the intervention. We concluded that although the present intervention successfully changed important cognitive determinants of drinking more is needed to change subsequent drinking behavior in at-risk adolescents.
Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu25 citations 25 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Pharmacology Biochem... arrow_drop_down Pharmacology Biochemistry and BehaviorArticle . 2007Data sources: DANS (Data Archiving and Networked Services)Pharmacology Biochemistry and BehaviorArticle . 2007 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefPharmacology Biochemistry and BehaviorArticle . 2007Data sources: Maastricht University | MUMC+ Research Informationadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.pbb.2006.07.023&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 DenmarkPublisher:Springer Science and Business Media LLC Fatouros, Dimitrios G.; Deen, Roshan; Arleth, Lise; Bergenstahl, Bjørn; Nielsen, Flemming Seier; Pedersen, Jan Skov; Müllertz, Anette;pmid: 17458683
To investigate the structural development of the colloid phases generated during lipolysis of a lipid-based formulation in an in vitro lipolysis model, which simulates digestion in the small intestine.Small-Angle X-Ray scattering (SAXS) coupled with the in vitro lipolysis model which accurately reproduces the solubilizing environment in the gastrointestinal tract and simulates gastrointestinal lipid digestion through the use of bile and pancreatic extracts. The combined method was used to follow the intermediate digestion products of a self nano emulsified drug delivery system (SNEDDS) under fasted conditions. SNEDDS is developed to facilitate the uptake of poorly soluble drugs.The data revealed that a lamellar phase forms immediately after initiation of lipolysis, whereas a hexagonal phase is formed after 60 min. The change of the relative amounts of these phases clearly demonstrates that lipolysis is a dynamic process. The formation of these phases is driven by the lipase which continuously hydrolyzes triglycerides from the oil-cores of the nanoemulsion droplets into mono- and diglycerides and fatty acids. We propose that this change of the over-all composition of the intestinal fluid with increased fraction of hydrolyzed nanoemulsion induces a change in the composition and effective critical packing parameter of the amphiphilic molecules, which determines the phase behavior of the system. Control experiments (only the digestion medium) or the surfactant (Cremophor RH 40) revealed the formation of a lamellar phase demonstrating that the hexagonal phase is due to the hydrolysis of the SNEDDS formulation.The current results demonstrate that SAXS measurements combined with the in vitro dynamic lipolysis model may be used to elucidate the processes encountered during the digestion of lipid-based formulations of poorly soluble drugs for oral drug delivery. Thus the combined methods may act as an efficient screening tool.
PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11095-007-9304-6&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu117 citations 117 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11095-007-9304-6&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2007 DenmarkPublisher:Springer Science and Business Media LLC Fatouros, Dimitrios G.; Deen, Roshan; Arleth, Lise; Bergenstahl, Bjørn; Nielsen, Flemming Seier; Pedersen, Jan Skov; Müllertz, Anette;pmid: 17458683
To investigate the structural development of the colloid phases generated during lipolysis of a lipid-based formulation in an in vitro lipolysis model, which simulates digestion in the small intestine.Small-Angle X-Ray scattering (SAXS) coupled with the in vitro lipolysis model which accurately reproduces the solubilizing environment in the gastrointestinal tract and simulates gastrointestinal lipid digestion through the use of bile and pancreatic extracts. The combined method was used to follow the intermediate digestion products of a self nano emulsified drug delivery system (SNEDDS) under fasted conditions. SNEDDS is developed to facilitate the uptake of poorly soluble drugs.The data revealed that a lamellar phase forms immediately after initiation of lipolysis, whereas a hexagonal phase is formed after 60 min. The change of the relative amounts of these phases clearly demonstrates that lipolysis is a dynamic process. The formation of these phases is driven by the lipase which continuously hydrolyzes triglycerides from the oil-cores of the nanoemulsion droplets into mono- and diglycerides and fatty acids. We propose that this change of the over-all composition of the intestinal fluid with increased fraction of hydrolyzed nanoemulsion induces a change in the composition and effective critical packing parameter of the amphiphilic molecules, which determines the phase behavior of the system. Control experiments (only the digestion medium) or the surfactant (Cremophor RH 40) revealed the formation of a lamellar phase demonstrating that the hexagonal phase is due to the hydrolysis of the SNEDDS formulation.The current results demonstrate that SAXS measurements combined with the in vitro dynamic lipolysis model may be used to elucidate the processes encountered during the digestion of lipid-based formulations of poorly soluble drugs for oral drug delivery. Thus the combined methods may act as an efficient screening tool.
PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11095-007-9304-6&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu117 citations 117 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert PURE Aarhus Universi... arrow_drop_down University of Copenhagen: ResearchArticle . 2007Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11095-007-9304-6&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Elsevier BV Authors: Stoelinga, P.J.W.;t dontogenic keratocysts (OKCs) are known for their ropensity to recur. The rate of recurrence is probaly largely depending on the mode of treatment used. nfortunately, there are only a few reliable studies vailable from which meaningful conclusions can be rawn with regard to the best possible treatment trategy. The main drawback of most studies is the etrospective nature of the study, the variable folow-up time, the lack of information about the perentage of patients available for follow-up, and the ack of details about the actual surgery. Many papers re written by pathologists who obviously are deending on the written and often incomplete notes of urgeons, hence the link with the clinical parameters s often based on less than optimal information. It is he aim of this article to present a rational treatment rotocol based on clinical and histologic studies.
Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.joms.2005.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu132 citations 132 popularity Top 10% influence Top 1% impulse Average Powered by BIP!
more_vert Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.joms.2005.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2005 NetherlandsPublisher:Elsevier BV Authors: Stoelinga, P.J.W.;t dontogenic keratocysts (OKCs) are known for their ropensity to recur. The rate of recurrence is probaly largely depending on the mode of treatment used. nfortunately, there are only a few reliable studies vailable from which meaningful conclusions can be rawn with regard to the best possible treatment trategy. The main drawback of most studies is the etrospective nature of the study, the variable folow-up time, the lack of information about the perentage of patients available for follow-up, and the ack of details about the actual surgery. Many papers re written by pathologists who obviously are deending on the written and often incomplete notes of urgeons, hence the link with the clinical parameters s often based on less than optimal information. It is he aim of this article to present a rational treatment rotocol based on clinical and histologic studies.
Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.joms.2005.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu132 citations 132 popularity Top 10% influence Top 1% impulse Average Powered by BIP!
more_vert Radboud Repository arrow_drop_down Journal of Oral and Maxillofacial SurgeryArticle . 2005 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefJournal of Oral and Maxillofacial SurgeryArticle . 2005Data sources: DANS (Data Archiving and Networked Services)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.joms.2005.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu