• Energy Research
• Restricted close
• medical and health sciences close

In this article is presented the preliminary evaluation of the performance of radiation transmission of glass block, used in support of photovoltaic cells, investigating different internal surface points of the block, which are subject to different shading during daylight hours. The aim is to establish how the edging setting, the only opaque element, can reduce the amount of light radiation during the day, introducing in this way a reduction of efficiency of the entire generation system. The generation system can be based on traditional photovoltaic cells or on the most suitable dye sensitized solar cells. An experimental measurement setup employing a microprocessor-based instrument has been created and a set of measures have been carried out. The measures prove that the shading effect at different irradiation angles do not affect significantly the lighting over the PV cell.

beta-Carotene and six xanthophylls (lutein, neoxanthin, violaxanthin, luteoxanthin, cryptoxanthin, and echinenone) have been identified and semiquantitatively or quantitatively determined in musts and port wines for the first time. An HPLC method was developed and compared with that of one based on thin layer cromatography with scanning densitometry. The most abundant carotenoids present in red grape varieties are beta-carotene and lutein. In wines, significant quantities of violaxanthin, luteoxanthin, and neoxanthin were found. This study was done with berries (skin and pulp), musts, and fortified wines. Some experiments were performed to follow carotenoid content from grapes to wines. Although the levels of beta-carotene and lutein found in fortified wines were lower than those found in musts, other xanthophylls, such as neoxanthin, violaxanthin, and luteoxanthin, exist in appreciable amounts in young ports.

Plant-soil feedback (PSF) describes the process whereby plant species modify the soil environment, which subsequently impacts the growth of the same or another plant species. Our aim was to explore PSF by two maize varieties (a landrace and a hybrid variety) and three arbuscular mycorrhizal fungi (AMF) species (Funneliformis mosseae, Claroideoglomus etunicatum, Gigaspora margarita, and the mixture). We carried out a pot experiment with a conditioning and a feedback phase to determine PSF with different species of AMF and with a non-mycorrhizal control. Sterilized soil was conditioned separately by each variety, with or without AMF; in the feedback phase, each soil community was used to grow each in its "home" soil and in the "away" soil. Plant performance was assessed as shoot biomass, phosphorus (P) concentration and P content, and fungal performance was assessed as mycorrhizal colonization and hyphal length density. Both maize varieties were differentially influenced by AMF in the conditioning phase. In the feedback phase, PSF was generally negative for non-mycorrhizal plants or when plants were colonized by G. margarita, whereas PSF was positive in the other three AMF treatments. When plants were grown on home soil, hyphal length density was larger than on away soil. We conclude that different maize varieties can strengthen positive plant-soil feedback for themselves through beneficial mutualists for themselves, but not across the maize varieties.

Isotretinoin is effective in the treatment of severe acne and rosacea. Both parent drug and its main metabolite 4-oxo-isotretinoin are potentially teratogenic compounds and contain a carboxylic acid moiety. In the presence of ethanol, naturally occurring as well as synthetic retinoids also containing a carboxylic acid moiety are capable of undergoing an ethyl esterification with the metabolic formation of more lipophilic compounds with a much longer terminal half-life.To determine if isotretinoin (13-cis-RA), its main metabolite 4-oxo-isotretinoin (4-oxo-13-cis-RA), and other possible metabolites in the presence or absence of ethanol are converted to their corresponding ethyl derivatives in patients with severe acne or rosacea after multiple isotretinoin dosing. In addition, pharmacokinetic parameters of the parent drug and its 4-oxo metabolite were determined.Eleven patients with severe acne or rosacea were treated with isotretinoin daily for 3 months and investigated pharmacokinetically during 24 h after 1 month of treatment and for up to 28 days after discontinuation of therapy. A possible influence of ethanol was evaluated using a simple self-administered questionnaire and by measuring serum ethanol levels during treatment. The concentrations of isotretinoin, 4-oxo-isotretinoin and possible ethylated and nonethylated metabolites were measured by reverse-phase high-performance liquid chromatography.Although seven of 11 patients had a considerable weekly alcohol intake, no endogenous synthesis of ethyl derivatives of isotretinoin, the main 4-oxo metabolite or the all-trans compounds was chromatographically detectable in any of the patients' plasma samples during the treatment period. Multiple dose pharmacokinetic data for the parent drug and its main metabolite were comparable to previous studies.The metabolism and pharmacokinetics of isotretinoin and its main metabolites are not influenced by ethanol during long-term isotretinoin treatment. After ceasing long-term isotretinoin therapy the recommended period of 1 month for using anticonceptive measures in fertile women seems adequate.

The potential impacts of climate change on human health in sub-Saharan Africa are wide-ranging, complex, and largely adverse. The region's Indigenous peoples are considered to be at heightened risk given their relatively poor health outcomes, marginal social status, and resource-based livelihoods; however, little attention has been given to these most vulnerable of the vulnerable. This paper contributes to addressing this gap by taking a bottom-up approach to assessing health vulnerabilities to climate change in two Batwa Pygmy communities in rural Uganda. Rapid Rural Appraisal and PhotoVoice field methods complemented by qualitative data analysis were used to identify key climate-sensitive, community-identified health outcomes, describe determinants of sensitivity at multiple scales, and characterize adaptive capacity of Batwa health systems. The findings stress the importance of human drivers of vulnerability and adaptive capacity and the need to address social determinants of health in order to reduce the potential disease burden of climate change.

Objective: BeweegKuur (Exercise Therapy) is a Dutch lifestyle programme in which participants are referred by a general practitioner (GP) to a lifestyle advisor. To support participants, regional and local alliances are established. The present study explored the successes and challenges associated with collaboration processes in local BeweegKuur alliances. Design: A qualitative explorative study. Setting: The Netherlands Institute for Sports and Physical Activity (NISB) initiated the Building BeweegKuur Alliances project to support local alliances. The BeweegKuur intervention is implemented by over 30 regional and about 150 local alliances throughout the Netherlands. Method: 12 in-depth interviews were held with coordinators of the alliances, and four focus groups were held with regional and local alliance partners. Results: Collaboration within the alliances is perceived as successful in integrating prevention and care. Challenges include the participation of sectors such as the local municipality and the sports sector, and the transition of BeweegKuur participants to local sports facilities. Conclusion: This study identifies three general conditions for successful coordinated action: (a) flexible protocols and management that allow for contextual adaptations; (b) making successes and challenges visible using facilitating methods and tools; and (c) time and funding to overcome differences of culture between different sectors, and to build trust.

AbstractAlthough canopy height has long been a focus of interest in ecology, it has remained difficult to study at large spatial scales. Recently, satellite‐borne LiDAR equipment produced the first systematic high resolution maps of vegetation height worldwide. Here we show that this new resource reveals three marked modes in tropical canopy height ~40, ~12, and ~2 m corresponding to forest, savanna, and treeless landscapes. The distribution of these modes is consistent with the often hypothesized forest‐savanna bistability and suggests that both states can be stable in areas with a mean annual precipitation between ~1,500 and ~2,000 mm. Although the canopy height states correspond largely to the much discussed tree cover states, there are differences, too. For instance, there are places with savanna‐like sparse tree cover that have a forest‐like high canopy, suggesting that rather than true savanna, those are thinned relicts of forest. This illustrates how complementary sets of remotely sensed indicators may provide increasingly sophisticated ways to study ecological phenomena at a global scale.