- Philip J. Landrigan; Stephen S Lim; Christopher J L Murray;
Howard Hu; Richard Fuller; Richard Fuller
Harvested from ORCID Public Data FileRichard Fuller in OpenAIREAccess Routesgold 8 citations 8 popularity Top 10% influence Average impulse Top 10% 
Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/s2542-5196(18)30189-x&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Philip J. Landrigan; Stephen S Lim; Christopher J L Murray; Howard Hu; Richard Fuller;
Richard Fuller
Harvested from ORCID Public Data FileRichard Fuller in OpenAIREAccess Routesgold 8 citations 8 popularity Top 10% influence Average impulse Top 10% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/s2542-5196(18)30189-x&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - UKRI| Automated manufacturing cost estimator and supply chain management portal ,NIH| Project 5: Green Remediation by Solar Energy Conversion Into Electrolysis ,NIH| Lifecourse Exposures & Diet: Epigenetics, Maturation & Metabolic Syndrome ,NIH| Sleep and Circadian Rhythms in Adolescence: Epigenetic Pathways of Cardiometabolic Risk ,NIH| Michigan Center on Lifestage Environmental Exposures and Disease ,NIH| E3Gen: Multigenerational Effects of Toxicant Exposures on Life Course Health and Neurocognitive Outcomes in the ELEMENT Birth Cohorts ,NIH| Prenatal and Childhood Exposure to Fluoride and Neurodevelopment ,NIH| Environmental exposures, early iron deficiency and child neurodevelopment ,NIH| LEAD DOSE BIOMARKERS, REPRODUCTION, AND INFANT OUTCOMES Astrid N. Zamora; Deborah J. Watkins; Karen E. Peterson;
Astrid N. Zamora
Harvested from ORCID Public Data FileAstrid N. Zamora in OpenAIRE Martha M. Téllez-Rojo; +5 AuthorsMartha M. Téllez-Rojo
Harvested from ORCID Public Data FileMartha M. Téllez-Rojo in OpenAIRE Astrid N. Zamora; Deborah J. Watkins; Karen E. Peterson;Astrid N. Zamora
Harvested from ORCID Public Data FileAstrid N. Zamora in OpenAIRE Martha M. Téllez-Rojo; Martha M. Téllez-Rojo
Harvested from ORCID Public Data FileMartha M. Téllez-Rojo in OpenAIRE Howard Hu; John D. Meeker; Alejandra Cantoral; Adriana Mercado-García;John D. Meeker
Harvested from ORCID Public Data FileJohn D. Meeker in OpenAIRE Erica C. Jansen; Erica C. Jansen
Harvested from ORCID Public Data FileErica C. Jansen in OpenAIREThe neurobiological processes involved in establishing sleep regulation are vulnerable to environmental exposures as early as seven weeks of gestation. Studies have linked in utero pesticide exposure to childhood sleep-disordered breathing. However, the impact of in utero pesticide exposure on the sleep health of adolescents remains unexplored.Data from 137 mother-adolescent pairs from a Mexico City cohort were analyzed. We used maternal urinary 3-phenoxybenzoic acid (3-PBA, pyrethroid metabolite) and 3, 5, 6-trichloro-2-pyridinol (TCPy, chlorpyrifos metabolite) from trimester three to estimate in utero pesticide exposure. Among adolescents, we obtained repeated measures of objectively assessed sleep duration, midpoint, and fragmentation using wrist-actigraphy devices for 7 consecutive days in 2015 and 2017. Unstratified and sex-stratified associations between maternal urinary 3-PBA and TCPy and adolescent sleep measures were examined using generalized linear mixed models (GLMMs). We also examined the interactive effects of maternal pesticide exposure and offspring sex on sleep outcomes.3-PBA and TCPy were detected in 44.4% and 93% of urine samples, respectively. Adjusted findings demonstrated that higher exposure to maternal TCPy was associated with longer sleep duration and later sleep timing. Findings from interaction tests between maternal pesticide exposure and offspring sex were not statistically significant, although adjusted sex-stratified findings showed that the association between TCPy with duration and midpoint was evident only among female offspring. To illustrate, those in the highest tertile of exposure had a 59 minute (95% CI: 12.2, 104.8) (p, trend = 0.004) longer sleep duration and a 0.6 hour (95% CI: 0.01, 1.3) (p, trend = 0.01) later sleep midpoint. We found no significant associations between 3-PBA and sleep outcomes.Within a cohort of mother-adolescent pairs, we found associations between maternal prenatal pesticide exposure and longer sleep duration and later sleep timing among adolescent offspring. Further, this association may be female-specific.
9 citations 9 popularity Top 10% influence Average impulse Top 10% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envres.2021.111977&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - UKRI| Automated manufacturing cost estimator and supply chain management portal ,NIH| Project 5: Green Remediation by Solar Energy Conversion Into Electrolysis ,NIH| Lifecourse Exposures & Diet: Epigenetics, Maturation & Metabolic Syndrome ,NIH| Sleep and Circadian Rhythms in Adolescence: Epigenetic Pathways of Cardiometabolic Risk ,NIH| Michigan Center on Lifestage Environmental Exposures and Disease ,NIH| E3Gen: Multigenerational Effects of Toxicant Exposures on Life Course Health and Neurocognitive Outcomes in the ELEMENT Birth Cohorts ,NIH| Prenatal and Childhood Exposure to Fluoride and Neurodevelopment ,NIH| Environmental exposures, early iron deficiency and child neurodevelopment ,NIH| LEAD DOSE BIOMARKERS, REPRODUCTION, AND INFANT OUTCOMES Astrid N. Zamora; Deborah J. Watkins; Karen E. Peterson;
Astrid N. Zamora
Harvested from ORCID Public Data FileAstrid N. Zamora in OpenAIRE Martha M. Téllez-Rojo; +5 AuthorsMartha M. Téllez-Rojo
Harvested from ORCID Public Data FileMartha M. Téllez-Rojo in OpenAIRE Astrid N. Zamora; Deborah J. Watkins; Karen E. Peterson;Astrid N. Zamora
Harvested from ORCID Public Data FileAstrid N. Zamora in OpenAIRE Martha M. Téllez-Rojo; Martha M. Téllez-Rojo
Harvested from ORCID Public Data FileMartha M. Téllez-Rojo in OpenAIRE Howard Hu; John D. Meeker; Alejandra Cantoral; Adriana Mercado-García;John D. Meeker
Harvested from ORCID Public Data FileJohn D. Meeker in OpenAIRE Erica C. Jansen; Erica C. Jansen
Harvested from ORCID Public Data FileErica C. Jansen in OpenAIREThe neurobiological processes involved in establishing sleep regulation are vulnerable to environmental exposures as early as seven weeks of gestation. Studies have linked in utero pesticide exposure to childhood sleep-disordered breathing. However, the impact of in utero pesticide exposure on the sleep health of adolescents remains unexplored.Data from 137 mother-adolescent pairs from a Mexico City cohort were analyzed. We used maternal urinary 3-phenoxybenzoic acid (3-PBA, pyrethroid metabolite) and 3, 5, 6-trichloro-2-pyridinol (TCPy, chlorpyrifos metabolite) from trimester three to estimate in utero pesticide exposure. Among adolescents, we obtained repeated measures of objectively assessed sleep duration, midpoint, and fragmentation using wrist-actigraphy devices for 7 consecutive days in 2015 and 2017. Unstratified and sex-stratified associations between maternal urinary 3-PBA and TCPy and adolescent sleep measures were examined using generalized linear mixed models (GLMMs). We also examined the interactive effects of maternal pesticide exposure and offspring sex on sleep outcomes.3-PBA and TCPy were detected in 44.4% and 93% of urine samples, respectively. Adjusted findings demonstrated that higher exposure to maternal TCPy was associated with longer sleep duration and later sleep timing. Findings from interaction tests between maternal pesticide exposure and offspring sex were not statistically significant, although adjusted sex-stratified findings showed that the association between TCPy with duration and midpoint was evident only among female offspring. To illustrate, those in the highest tertile of exposure had a 59 minute (95% CI: 12.2, 104.8) (p, trend = 0.004) longer sleep duration and a 0.6 hour (95% CI: 0.01, 1.3) (p, trend = 0.01) later sleep midpoint. We found no significant associations between 3-PBA and sleep outcomes.Within a cohort of mother-adolescent pairs, we found associations between maternal prenatal pesticide exposure and longer sleep duration and later sleep timing among adolescent offspring. Further, this association may be female-specific.
9 citations 9 popularity Top 10% influence Average impulse Top 10% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envres.2021.111977&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Ramesh C. Dhiman; Carina J. Gronlund;
Carina J. Gronlund
Harvested from ORCID Public Data FileCarina J. Gronlund in OpenAIRE Arun Agrawal; Arun Agrawal
Harvested from ORCID Public Data FileArun Agrawal in OpenAIRE Howard Hu; +17 AuthorsRamesh C. Dhiman; Carina J. Gronlund; Carina J. Gronlund
Harvested from ORCID Public Data FileCarina J. Gronlund in OpenAIRE Arun Agrawal; Arun Agrawal
Harvested from ORCID Public Data FileArun Agrawal in OpenAIRE Howard Hu; R S Dhaliwal; Howard Frumkin; Howard Frumkin
Harvested from ORCID Public Data FileHoward Frumkin in OpenAIRE Stuart Batterman; Mark L. Wilson; Jeremy J. Hess;Stuart Batterman
Harvested from ORCID Public Data FileStuart Batterman in OpenAIRE Daniel G. Brown; George Luber;Daniel G. Brown
Harvested from ORCID Public Data FileDaniel G. Brown in OpenAIRE S Rani Kotha; Tanvir Kaur; Kathleen F. Bush;S Rani Kotha
Harvested from ORCID Public Data FileS Rani Kotha in OpenAIRE Richard B. Rood; Mercedes Pascual; Mercedes Pascual; Joseph N. S. Eisenberg; Aley Joseph; Vikas Kapil;Richard B. Rood
Harvested from ORCID Public Data FileRichard B. Rood in OpenAIRE Kalpana Balakrishnan; Kalpana Balakrishnan
Harvested from ORCID Public Data FileKalpana Balakrishnan in OpenAIREClimate change and associated increases in climate variability will likely further exacerbate global health disparities. More research is needed, particularly in developing countries, to accurately predict the anticipated impacts and inform effective interventions.Building on the information presented at the 2009 Joint Indo-U.S. Workshop on Climate Change and Health in Goa, India, we reviewed relevant literature and data, addressed gaps in knowledge, and identified priorities and strategies for future research in India.The scope of the problem in India is enormous, based on the potential for climate change and variability to exacerbate endemic malaria, dengue, yellow fever, cholera, and chikungunya, as well as chronic diseases, particularly among the millions of people who already experience poor sanitation, pollution, malnutrition, and a shortage of drinking water. Ongoing efforts to study these risks were discussed but remain scant. A universal theme of the recommendations developed was the importance of improving the surveillance, monitoring, and integration of meteorological, environmental, geospatial, and health data while working in parallel to implement adaptation strategies.It will be critical for India to invest in improvements in information infrastructure that are innovative and that promote interdisciplinary collaborations while embarking on adaptation strategies. This will require unprecedented levels of collaboration across diverse institutions in India and abroad. The data can be used in research on the likely impacts of climate change on health that reflect India's diverse climates and populations. Local human and technical capacities for risk communication and promoting adaptive behavior must also be enhanced.
Access RoutesGreen gold 68 citations 68 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1289/ehp.1003000&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Ramesh C. Dhiman; Carina J. Gronlund;
Carina J. Gronlund
Harvested from ORCID Public Data FileCarina J. Gronlund in OpenAIRE Arun Agrawal; Arun Agrawal
Harvested from ORCID Public Data FileArun Agrawal in OpenAIRE Howard Hu; +17 AuthorsRamesh C. Dhiman; Carina J. Gronlund; Carina J. Gronlund
Harvested from ORCID Public Data FileCarina J. Gronlund in OpenAIRE Arun Agrawal; Arun Agrawal
Harvested from ORCID Public Data FileArun Agrawal in OpenAIRE Howard Hu; R S Dhaliwal; Howard Frumkin; Howard Frumkin
Harvested from ORCID Public Data FileHoward Frumkin in OpenAIRE Stuart Batterman; Mark L. Wilson; Jeremy J. Hess;Stuart Batterman
Harvested from ORCID Public Data FileStuart Batterman in OpenAIRE Daniel G. Brown; George Luber;Daniel G. Brown
Harvested from ORCID Public Data FileDaniel G. Brown in OpenAIRE S Rani Kotha; Tanvir Kaur; Kathleen F. Bush;S Rani Kotha
Harvested from ORCID Public Data FileS Rani Kotha in OpenAIRE Richard B. Rood; Mercedes Pascual; Mercedes Pascual; Joseph N. S. Eisenberg; Aley Joseph; Vikas Kapil;Richard B. Rood
Harvested from ORCID Public Data FileRichard B. Rood in OpenAIRE Kalpana Balakrishnan; Kalpana Balakrishnan
Harvested from ORCID Public Data FileKalpana Balakrishnan in OpenAIREClimate change and associated increases in climate variability will likely further exacerbate global health disparities. More research is needed, particularly in developing countries, to accurately predict the anticipated impacts and inform effective interventions.Building on the information presented at the 2009 Joint Indo-U.S. Workshop on Climate Change and Health in Goa, India, we reviewed relevant literature and data, addressed gaps in knowledge, and identified priorities and strategies for future research in India.The scope of the problem in India is enormous, based on the potential for climate change and variability to exacerbate endemic malaria, dengue, yellow fever, cholera, and chikungunya, as well as chronic diseases, particularly among the millions of people who already experience poor sanitation, pollution, malnutrition, and a shortage of drinking water. Ongoing efforts to study these risks were discussed but remain scant. A universal theme of the recommendations developed was the importance of improving the surveillance, monitoring, and integration of meteorological, environmental, geospatial, and health data while working in parallel to implement adaptation strategies.It will be critical for India to invest in improvements in information infrastructure that are innovative and that promote interdisciplinary collaborations while embarking on adaptation strategies. This will require unprecedented levels of collaboration across diverse institutions in India and abroad. The data can be used in research on the likely impacts of climate change on health that reflect India's diverse climates and populations. Local human and technical capacities for risk communication and promoting adaptive behavior must also be enhanced.
Access RoutesGreen gold 68 citations 68 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1289/ehp.1003000&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Hao Yin; Bhavna Sharma;
Bhavna Sharma
Harvested from ORCID Public Data FileBhavna Sharma in OpenAIRE Howard Hu; Fei Liu; +4 Authors Hao Yin; Bhavna Sharma; Bhavna Sharma
Harvested from ORCID Public Data FileBhavna Sharma in OpenAIRE Howard Hu; Fei Liu; Mehak Kaur; Gary Cohen; Rob McConnell;Mehak Kaur
Harvested from ORCID Public Data FileMehak Kaur in OpenAIRE Sandrah P. Eckel; Sandrah P. Eckel
Harvested from ORCID Public Data FileSandrah P. Eckel in OpenAIREHealth care accounts for 9-10% of greenhouse gas (GHG) emissions in the United States. Strategies for monitoring these emissions at the hospital level are needed to decarbonize the sector. However, data collection to estimate emissions is challenging, especially for smaller hospitals. We explored the potential of gradient boosting machines (GBM) to impute missing data on resource consumption in the 2020 survey of a consortium of 283 hospitals participating in Practice Greenhealth. GBM imputed missing values for selected variables in order to predict electricity use and beef consumption (R2=0.82) and anesthetic gas desflurane use (R2=0.51), using administrative data readily available for most hospitals. After imputing missing consumption data, estimated GHG emissions associated with these three examples totaled over 3 million metric tons of CO2 equivalent emissions (MTCO2e). Specifically, electricity consumption had the largest total carbon footprint (2.4 MTCO2e), followed by beef (0.6 million MTCO2e) and desflurane consumption (0.03 million MTCO2e) across the 283 hospitals. The approach should be applicable to other sources of hospital GHGs in order to estimate total emissions of individual hospitals and to refine survey questions to help develop better intervention strategies.
Access Routesgold 5 citations 5 popularity Average influence Average impulse Top 10% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.cesys.2023.100155&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - Hao Yin; Bhavna Sharma;
Bhavna Sharma
Harvested from ORCID Public Data FileBhavna Sharma in OpenAIRE Howard Hu; Fei Liu; +4 Authors Hao Yin; Bhavna Sharma; Bhavna Sharma
Harvested from ORCID Public Data FileBhavna Sharma in OpenAIRE Howard Hu; Fei Liu; Mehak Kaur; Gary Cohen; Rob McConnell;Mehak Kaur
Harvested from ORCID Public Data FileMehak Kaur in OpenAIRE Sandrah P. Eckel; Sandrah P. Eckel
Harvested from ORCID Public Data FileSandrah P. Eckel in OpenAIREHealth care accounts for 9-10% of greenhouse gas (GHG) emissions in the United States. Strategies for monitoring these emissions at the hospital level are needed to decarbonize the sector. However, data collection to estimate emissions is challenging, especially for smaller hospitals. We explored the potential of gradient boosting machines (GBM) to impute missing data on resource consumption in the 2020 survey of a consortium of 283 hospitals participating in Practice Greenhealth. GBM imputed missing values for selected variables in order to predict electricity use and beef consumption (R2=0.82) and anesthetic gas desflurane use (R2=0.51), using administrative data readily available for most hospitals. After imputing missing consumption data, estimated GHG emissions associated with these three examples totaled over 3 million metric tons of CO2 equivalent emissions (MTCO2e). Specifically, electricity consumption had the largest total carbon footprint (2.4 MTCO2e), followed by beef (0.6 million MTCO2e) and desflurane consumption (0.03 million MTCO2e) across the 283 hospitals. The approach should be applicable to other sources of hospital GHGs in order to estimate total emissions of individual hospitals and to refine survey questions to help develop better intervention strategies.
Access Routesgold 5 citations 5 popularity Average influence Average impulse Top 10% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.cesys.2023.100155&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - NIH| Stress-Lead Interactions and Child Development ,NIH| SUPERFUND TOXIC SUBSTANCES--EXPOSURE AND DISEASE ,NIH| Metal Neurotoxicity ,NIH| Project 5: Green Remediation by Solar Energy Conversion Into Electrolysis ,NIH| Bisphenol A and Phthalate Exposure in Relation to Fetal Growth and Preterm Birth ,NIH| Stress-Chemical Interactions and Neurobehavior in School Age Children ,NIH| LEAD DOSE BIOMARKERS, REPRODUCTION, AND INFANT OUTCOMES ,NIH| Metal Mixtures and Neurodevelopment ,NIH| NEUROCHEMICAL AND GENETIC MARKERS OF LEAD TOXICITYAntonia M. Calafat; Héctor Lamadrid-Figueroa;
Héctor Lamadrid-Figueroa
Harvested from ORCID Public Data FileHéctor Lamadrid-Figueroa in OpenAIRE Howard Hu; Howard Hu; +7 AuthorsAntonia M. Calafat; Héctor Lamadrid-Figueroa; Héctor Lamadrid-Figueroa
Harvested from ORCID Public Data FileHéctor Lamadrid-Figueroa in OpenAIRE Howard Hu; Howard Hu; Howard Hu; Adriana Mercado-García; Brisa N. Sánchez; Martha María Téllez-Rojo; Gamola Z. Fortenberry; David E. Cantonwine;Brisa N. Sánchez
Harvested from ORCID Public Data FileBrisa N. Sánchez in OpenAIRE John D. Meeker; John D. Meeker
Harvested from ORCID Public Data FileJohn D. Meeker in OpenAIREPresence of Bisphenol A (BPA) has been documented worldwide in a variety of human biological samples. There is growing evidence that low level BPA exposure may impact placental tissue development and thyroid function in humans. The aim of this present pilot study was to determine urinary concentrations of BPA during the last trimester of pregnancy among a small subset of women in Mexico City, Mexico and relate these concentrations to risk of delivering prematurely.A nested case-control subset of 60 participants in the Early Life Exposure in Mexico to ENvironmental Toxicants (ELEMENT) study in Mexico City, Mexico were selected based on delivering less than or equal to 37 weeks of gestation and greater than 37 weeks of gestation. Third trimester archived spot urine samples were analyzed by online solid phase extraction coupled with high performance liquid chromatography isotope dilution tandem mass spectrometry.BPA was detected in 80.0% (N = 48) of the urine samples; total concentrations ranged from < 0.4 μg/L to 6.7 μg/L; uncorrected geometric mean was 1.52 μg/L. The adjusted odds ratio of delivering less than or equal to 37 weeks in relation to specific gravity adjusted third trimester BPA concentration was 1.91 (95%CI 0.93, 3.91, p-value = 0.08). When cases were further restricted to births occurring prior to the 37th week (n = 12), the odds ratio for specific-gravity adjusted BPA was larger and statistically significant (p < 0.05).This is the first study to document measurable levels of BPA in the urine of a population of Mexican women. This study also provides preliminary evidence, based on a single spot urine sample collected during the third trimester, that pregnant women who delivered less than or equal to 37 weeks of gestation and prematurely (< 37 weeks) had higher urinary concentrations of BPA compared to women delivering after 37 weeks.
Access RoutesGreen gold 158 citations 158 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/1476-069x-9-62&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu - NIH| Stress-Lead Interactions and Child Development ,NIH| SUPERFUND TOXIC SUBSTANCES--EXPOSURE AND DISEASE ,NIH| Metal Neurotoxicity ,NIH| Project 5: Green Remediation by Solar Energy Conversion Into Electrolysis ,NIH| Bisphenol A and Phthalate Exposure in Relation to Fetal Growth and Preterm Birth ,NIH| Stress-Chemical Interactions and Neurobehavior in School Age Children ,NIH| LEAD DOSE BIOMARKERS, REPRODUCTION, AND INFANT OUTCOMES ,NIH| Metal Mixtures and Neurodevelopment ,NIH| NEUROCHEMICAL AND GENETIC MARKERS OF LEAD TOXICITYAntonia M. Calafat; Héctor Lamadrid-Figueroa;
Héctor Lamadrid-Figueroa
Harvested from ORCID Public Data FileHéctor Lamadrid-Figueroa in OpenAIRE Howard Hu; Howard Hu; +7 AuthorsAntonia M. Calafat; Héctor Lamadrid-Figueroa; Héctor Lamadrid-Figueroa
Harvested from ORCID Public Data FileHéctor Lamadrid-Figueroa in OpenAIRE Howard Hu; Howard Hu; Howard Hu; Adriana Mercado-García; Brisa N. Sánchez; Martha María Téllez-Rojo; Gamola Z. Fortenberry; David E. Cantonwine;Brisa N. Sánchez
Harvested from ORCID Public Data FileBrisa N. Sánchez in OpenAIRE John D. Meeker; John D. Meeker
Harvested from ORCID Public Data FileJohn D. Meeker in OpenAIREPresence of Bisphenol A (BPA) has been documented worldwide in a variety of human biological samples. There is growing evidence that low level BPA exposure may impact placental tissue development and thyroid function in humans. The aim of this present pilot study was to determine urinary concentrations of BPA during the last trimester of pregnancy among a small subset of women in Mexico City, Mexico and relate these concentrations to risk of delivering prematurely.A nested case-control subset of 60 participants in the Early Life Exposure in Mexico to ENvironmental Toxicants (ELEMENT) study in Mexico City, Mexico were selected based on delivering less than or equal to 37 weeks of gestation and greater than 37 weeks of gestation. Third trimester archived spot urine samples were analyzed by online solid phase extraction coupled with high performance liquid chromatography isotope dilution tandem mass spectrometry.BPA was detected in 80.0% (N = 48) of the urine samples; total concentrations ranged from < 0.4 μg/L to 6.7 μg/L; uncorrected geometric mean was 1.52 μg/L. The adjusted odds ratio of delivering less than or equal to 37 weeks in relation to specific gravity adjusted third trimester BPA concentration was 1.91 (95%CI 0.93, 3.91, p-value = 0.08). When cases were further restricted to births occurring prior to the 37th week (n = 12), the odds ratio for specific-gravity adjusted BPA was larger and statistically significant (p < 0.05).This is the first study to document measurable levels of BPA in the urine of a population of Mexican women. This study also provides preliminary evidence, based on a single spot urine sample collected during the third trimester, that pregnant women who delivered less than or equal to 37 weeks of gestation and prematurely (< 37 weeks) had higher urinary concentrations of BPA compared to women delivering after 37 weeks.
Access RoutesGreen gold 158 citations 158 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.<script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1186/1476-069x-9-62&type=result"></script>'); --> </script>For further information contact us at helpdesk@openaire.eu
