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description Publicationkeyboard_double_arrow_right Article , Journal 1993 United KingdomPublisher:Springer Science and Business Media LLC Authors:Chaudhuri, K. Ray;
Maule, S.; Thomaides, T.; Pavitt, D.; +2 AuthorsChaudhuri, K. Ray
Chaudhuri, K. Ray in OpenAIREChaudhuri, K. Ray;
Maule, S.; Thomaides, T.; Pavitt, D.; Mathias, C. J.; Ray Chaudhuri, Kallol;Chaudhuri, K. Ray
Chaudhuri, K. Ray in OpenAIREdoi: 10.1007/bf00868341
pmid: 8164016
Patients with pure autonomic failure (PAF) and multiple system atrophy (MSA) may complain of feeling light-headed after alcohol ingestion particularly on assumption of the upright posture. The reasons for this have not been investigated. We therefore studied the effects of oral alcohol (40% vodka in sugar-free orange juice) and placebo (juice only) on the systemic and regional (including superior mesenteric artery, SMA) blood flow in nine patients with PAF and six patients with MSA. After alcohol, there was a fall in supine blood pressure (BP) and vasodilatation in the SMA but no change in cardiac output, or forearm muscle and cutaneous blood flow in either PAF or MSA; BP fell further during head-up tilt with no changes in levels of plasma catecholamines. After placebo, there were no changes while supine. We conclude that alcohol lowers supine BP and dilates the SMA with no change in muscle or cutaneous blood flow. Alcohol also enhances the fall in BP during head-up tilt. This may explain the symptoms experienced by PAF and MSA patients after alcohol.
Journal of Neurology arrow_drop_down King's College, London: Research PortalArticle . 1994Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/bf00868341&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu31 citations 31 popularity Top 10% influence Top 10% impulse Average Powered by BIP!
more_vert Journal of Neurology arrow_drop_down King's College, London: Research PortalArticle . 1994Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/bf00868341&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 1993 United KingdomPublisher:Springer Science and Business Media LLC Authors:Chaudhuri, K. Ray;
Maule, S.; Thomaides, T.; Pavitt, D.; +2 AuthorsChaudhuri, K. Ray
Chaudhuri, K. Ray in OpenAIREChaudhuri, K. Ray;
Maule, S.; Thomaides, T.; Pavitt, D.; Mathias, C. J.; Ray Chaudhuri, Kallol;Chaudhuri, K. Ray
Chaudhuri, K. Ray in OpenAIREdoi: 10.1007/bf00868341
pmid: 8164016
Patients with pure autonomic failure (PAF) and multiple system atrophy (MSA) may complain of feeling light-headed after alcohol ingestion particularly on assumption of the upright posture. The reasons for this have not been investigated. We therefore studied the effects of oral alcohol (40% vodka in sugar-free orange juice) and placebo (juice only) on the systemic and regional (including superior mesenteric artery, SMA) blood flow in nine patients with PAF and six patients with MSA. After alcohol, there was a fall in supine blood pressure (BP) and vasodilatation in the SMA but no change in cardiac output, or forearm muscle and cutaneous blood flow in either PAF or MSA; BP fell further during head-up tilt with no changes in levels of plasma catecholamines. After placebo, there were no changes while supine. We conclude that alcohol lowers supine BP and dilates the SMA with no change in muscle or cutaneous blood flow. Alcohol also enhances the fall in BP during head-up tilt. This may explain the symptoms experienced by PAF and MSA patients after alcohol.
Journal of Neurology arrow_drop_down King's College, London: Research PortalArticle . 1994Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/bf00868341&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu31 citations 31 popularity Top 10% influence Top 10% impulse Average Powered by BIP!
more_vert Journal of Neurology arrow_drop_down King's College, London: Research PortalArticle . 1994Data sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/bf00868341&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu