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Description of the four files: contacts.xlsx List of detected contacts for the three case studies pymol_files_case_study_1.zip Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 1: comparison between contacts of myoglobin against hemoglobin pymol_files_case_study_2.zip Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 2: comparison between contacts of RBDs of SARS-CoV-1 vs. SARS-CoV-2 both complexed with the cell receptor ACE2 pymol_files_case_study_3.zip Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 3: comparison between contacts of glucose-tolerant vs. non-tolerant β-glucosidases

Nearly three billion people in low- and middle-income countries (LMICs) rely on polluting fuels, resulting in millions of avoidable deaths annually. Polluting fuels also emit short-lived climate forcers and greenhouse gases (GHGs). Liquefied petroleum gas (LPG) and grid-based electricity are scalable alternatives to polluting fuels but have raised climate and health concerns. Here, we compare emissions and climate impacts of a business-as-usual household cooking fuel trajectory to four large-scale transitions to gas and/or grid electricity in 77 LMICs. We account for upstream and end-use emissions from gas and electric cooking, assuming electrical grids evolve according to the 2022 World Energy Outlook’s “Stated Policies” Scenario. We input the emissions into a reduced-complexity climate model to estimate radiative forcing and temperature changes associated with each scenario. We find full transitions to LPG and/or electricity decrease emissions from both well-mixed GHG and short-lived climate forcers, resulting in a roughly 5 millikelvin global temperature reduction by 2040. Transitions to LPG and/or electricity also reduce annual emissions of PM2.5 by over 6 Mt (99%) by 2040, which would substantially lower health risks from Household Air Pollution. Primary input data was collected from the following sources: Baseline household fuel choices - WHO household energy database (https://www.nature.com/articles/s41467-021-26036-x) End-use emissions - US EPA lifecycle assessment of household fuels (https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=339679&Lab=NRMRL&simplesearch=0&showcriteria=2&sortby=pubDate&timstype=Published+Report&datebeginpublishedpresented) Upstream emissions - Argonne National Labs GREET Model (https://greet.es.anl.gov/index.php) Current and future population estimates - UNECA (http://data.un.org/Explorer.aspx?d=EDATA) Input data was processed by defining household fuel choice scenarios, estimating national household fuel consumption based on these scenarios, and applying fuel-specific emission factors to create country-specific emission pathways. These emission pathways were input into the FaIR model (https://zenodo.org/record/5513022#.Yt_jfHbMLb0) which generated additional data for each scenario including time series of pollution concentrations, radiative forcing, and temperature changes. All data is provided in CSV format. Nothing proprietary is required. 

Variation in food resources can result in dramatic fluctuations in the body condition of animals dependent on those resources. Decreases in body mass can disrupt patterns of energy allocation and impose stress, thereby altering immune function. In this study we investigated links between changes in body mass of captive cane toads (Rhinella marina), their circulating white blood cell populations, and their performance in immune assays. Captive toads that lost weight over a 3-month period had increased levels of monocytes and heterophils and reduced levels of eosinophils. Basophil and lymphocyte levels were unrelated to changes in mass. Because individuals that lost mass had higher heterophil levels but stable lymphocyte levels, the ratio of these cell types was also higher, partially consistent with a stress response. Phagocytic ability of whole blood was higher in toads that lost mass, due to increased circulating levels of phagocytic cells. Other measures of immune performance were unrelated to mass change. These results highlight the challenges faced by invasive species as they expand their range into novel environments which may impose substantial seasonal changes in food availability that were not present in the native range. Individuals facing energy restrictions may shift their immune function towards more economical and general avenues of combating pathogens.

{"references": ["Liu, Z., Ciais, P., Deng, Z., Lei, R., Davis, S. J., Feng, S., Zheng, B., Cui, D., Dou, X., Zhu, B., Guo, R., Ke, P., Sun, T., Lu, C., He, P., Wang, Y., Yue, X., Wang, Y., Lei, Y., Zhou, H., Cai, Z., Wu, Y., Guo, R., Han, T., Xue, J., Boucher, O., Boucher, E., Chevallier, F., Tanaka, K., Wei, Y., Zhong, H., Kang, C., Zhang, N., Chen, B., Xi, F., Liu, M., Br\u00e9on, F.-M., Lu, Y., Zhang, Q., Guan, D., Gong, P., Kammen, D. M., He, K. & Schellnhuber, H. J. (2020). Near-real-time monitoring of global CO2 emissions reveals the effects of the COVID-19 pandemic. Nature Communications 11, 5172 (2020). https://doi.org/10.1038/s41467-020-18922-7", "Meinshausen, M., Smith, S. J., Calvin, K., Daniel, J. S., Kainuma, M. L. T., Lamarque, J. F., Matsumoto, K., Montzka, S. A., Raper, S. C. B., Riahi, K., Thomson, A., Velders, G. J. M., & van Vuuren, D. P. (2011). The RCP greenhouse gas concentrations and their extensions from 1765 to 2300. Climatic Change, 109(1\u20132), 213\u2013241. https://doi.org/10.1007/s10584-011-0156-z", "Moss, R. H., Edmonds, J. A., Hibbard, K. A., Manning, M. R., Rose, S. K., van Vuuren, D. P., Carter, T. R., Emori, S., Kainuma, M., Kram, T., Meehl, G. A., Mitchell, J. F. B., Nakicenovic, N., Riahi, K., Smith, S. J., Stouffer, R. J., Thomson, A. M., Weyant, J. P. & Wilbanks, T. J. (2010). The next generation of scenarios for climate change research and assessment. Nature, 463(7282), 747\u2013756. https://doi.org/10.1038/nature08823", "Myhre, G., Highwood, E. J., Shine, K. P., & Stordal, F. (1998). New estimates of radiative forcing due to well mixed greenhouse gases. Geophysical Research Letters, 25(14), 2715\u20132718. https://doi.org/10.1029/98gl01908", "Strassmann, K. M. and Joos, F. (2018). The Bern Simple Climate Model (BernSCM) v1.0: an extensible and fully documented open-source re-implementation of the Bern reduced-form model for global carbon cycle\u2013climate simulations, Geosci. Model Dev., 11, 1887\u20131908, https://doi.org/10.5194/gmd-11-1887-2018", "Thomas, M. A., and Lin, T. (2018). A dual model for emulation of thermosteric and dynamic sea-level change. Climatic Change, 148(1\u20132), 311\u2013324. https://doi.org/10.1007/s10584-018-2198-y"]} Supplementary materials for Gonzalez, A. R., & Lin, T. (2022). Translated Emission Pathways (TEPs): Long-Term Simulations of COVID-19 CO2 Emissions and Thermosteric Sea Level Rise Projections. Earth's Future. In Press. Summary: This study introduces climate science to a broader audience by presenting an accessible research framework and environmental data related to the ongoing COVID-19 pandemic. A series of translated emission pathways (TEPs) were constructed based on the CO2 emission patterns from the various phases of COVID-19 response. In addition to resembling the forcing scenarios used within climate research, a thermosteric sea level rise analysis was incorporated to further emphasize the environmental benefits that can be obtained from long-term sustainability. As a promising start for including the general public in climate change discussion, this research promotes collective environmental action that mirrors the recommendations of the scientific community. We acknowledge the Carbon Monitor initiative (Liu et al., 2020) for providing the COVID-19 CO2 sectoral emission data used to construct the proposed TEPs. In addition, we acknowledge the developers of the BernSCM (Strassmann and Joos, 2018) that was utilized in this study to relate TEP CO2 emissions to their respective CO2 atmospheric concentrations. Furthermore, we thank the Texas Tech University McNair Scholars Program and the Multi-Hazard Sustainability (HazSus) research group for guidance and support throughout the course of this study. Analyses presented herein were performed using the RedRaider computing cluster at Texas Tech University. We thank the team at the High Performance Computing Center (HPCC) for their generous support. In addition, the equipment support from the Vice President for Research & Innovation for T.L.'s HazSus Research Group is gratefully acknowledged.

{"references": ["T Gopinathan, K P Arul Shri: Simulation of Recharging Battery of the\nPacemaker using Piezoelectric Crystal from the Pulse in Aorta, Thesis,\nDec 2011.", "H.W. Ko: US Patent 3456134A: Piezoelectric Energy Converter for\nElectronic Implants, 1969.", "A. Badel: R\u00e9cup\u00e9ration d'Energie et Contr\u00f4le Vibratoire par El\u00e9ments\nPi\u00e9zo\u00e9lectriques Suivant une Approche Non Lin\u00e9aire, Ph.D. Thesis,\nUniversit\u00e9 de Savoie, 2008.", "M. Deterre: Toward an Energy Harvester for Leadless Pacemakers,\nPh.D. Thesis, Paris-Sud Univ. 2013.", "N. Andrew: Redington,CardiacDept, Brompton Hospital, Fulham Road,\nLondon SW3 6HP, in press.", "R. White, G. Savage, M. Zdeblick: US Patent 7729768 B2: Implantable\nCardiac Motion Powered Piezoelectric Energy Source.", "S. Priya, D.J. Inman: Energy Harvesting Technologies.", "N. Bassiri-Gharb : Piezoelectric Mems: Materials and Devices,\nPiezoelectric and Acoustic Materials for Transducer Applications, A.\nSafari, E.K. Akdogan, eds., Springer US, 2008, pp. 413\u2013430.", "W. Clark, C. Mo : Energy Harvesting Technologies, Ch.16, pp.405-430,\nS. Priya, D.J. Inman eds., Springer, 2009.\n[10] M. Deterre, E. Lefeuvre, E. Dufour-Gergam : An Active Piezoelectric\nEnergy Extraction Method for Pressure Energy Harvesting, Smart\nMaterials and Structures, Vol.21(8), 085004, 2012.\n[11] M.A. Karami, D.J. Inman: Powering Pacemakers from Heartbeat\nVibrations Using Linear and Nonlinear Energy Harvesters, Appl. Phys.\nLett. 100, 042901 (2012), in press.\n[12] S.R Anton, H.A Sodano : A Review of Power Harvesting Using\nPiezoelectric Materials (2003\u20132006), Smart Materials and Structures,\nVol.16(3), R1, 2007."]} Present project consists in a study and a development of piezoelectric devices for supplying power to new generation pacemakers. They are miniaturized leadless implants without battery placed directly in right ventricle. Amongst different acceptable energy sources in cardiac environment, we choose the solution of a device based on conversion of the energy produced by pressure variation inside the heart into electrical energy. The proposed energy harvesters can meet the power requirements of pacemakers, and can be a good solution to solve the problem of regular surgical operation. With further development, proposed device should provide enough energy to allow pacemakers autonomy, and could be good candidate for next pacemaker generation.

Miniaturization of electrochemical detection ofPseudomonas aeruginosaquorum sensing molecules at a liquid/liquid interface through facilitated proton transfer reactions.

Many European countries are implementing long-term programmes for health protection from climate change. These programmes are based on World Health Assembly Resolution. European office of World Health Organisation studies the data and supports capacity building initiatives in order to strengthen healthcare system response to climate change and to ensure that health issues are considered when decisions are made in other sectors related to health – power industry and transportation. The article analyses strategic approaches of European countries to prevention programme development in response to global climate and environment change caused by anthropogenic activities in the context of influence of such process on human health. Climate change poses a considerable threat for human health and changes our understanding of protection measures for vulnerable populations. Проект № 2016-2592/001-001, 574826-EPP-1-2016-1-RU-EPPJMO-MODULE, при финансовой поддержке Европейской Комиссии

{"references": ["BENAZZOU L. et al (2021), \u00ab Covid-19 : An unexpected lever for accelerating the transformation of organizations in Morocco \u00bb, International journal of management sciences. Vol.4, n\u00b02 (2021)", "ELWARDI K. et al (2021), \u00ab Management of the Covid19 crisis : Case of a Moroccan public hospital \u00bb,International journal of management sciences. Vol.4, n\u00b02 (2021)", "De Briey V. (2005), \u00ab Spotlight on microfinance in 2005 \u00bb, Regards Economique, n\u00b028, Mars, pp.", "CAMPION, A. (2003), \"Improving internal control. Practical guide for use by microfinance institutions \", Practical Guide n \u00b0 1, June.", "ALCHIAN A. (1969), \u00ab Corporate Management and Property Rights: Economic Policy and the Regulation of Corporate Securities \u00bb, (publishedby H. Manne, Washington D.C.), American Institute for Public Policy Research.", "DEMSETZ H. (1967), \"Towards a Theory of Property Rights\", American Economic Review, May, pp.347-359.", "FURUBOTN E. & PEJOVITCH S. (1972), \"Property Rights and Economic Theory: A Survey of Recent Literature\", Journal of Economic Literature, December", "ALESSI de L. (1983), \u00ab Property Rights, Transaction Costs and The X-efficiency \u00bb, American Economic Review, vol. 73, n\u00b0 1, March, p. 64-81", "AMANN, B., (1999), \u00ab The theory of property rights \u00bb, in Koenig G\u00e9rard (ed.), New Theories for Managing the Enterprise of the XXIst Century, Economica, Paris, 13-60"]} The end of decade 1990 is marked by the proliferation of microfinance institutions that constitute powerful instruments for fight against poverty and the reduction of unemployment. In the meanwhile, considering the ephemeral character of some of those institutions, the object of this study is to understand the elements that are at the basis of the life expectancy of microfinance institutions in Cameroun in covid 19 context. The literature shows that variables such as a system of internal control and financial objectives influence the longevity of microfinance institutions. The test of chisquare on 35 institutions of microfinance observed within the period of 2004-2020 in Cameroun enable to establish connexions among variables. The results obtained show that the survival of microfinance institutions in Cameroun depends on internal control systems the board of directors, the separation of functions of president and that of general manager, the frequency of meeting of the board of directors, the effective presence participation of the members of the board of directors to the meetings and the joint decision making by the boards of directors and the general management.