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Yeast volatiles double starvation survival in Drosophila .

Yeast volatiles double starvation survival in Drosophila .

The solutions-based design framework of permaculture exhibits transformative potential, working to holistically integrate natural and human systems toward a more just society. The term can be defined and applied in a breadth of ways, contributing to both strengths and weaknesses for its capacity toward change. To explore the tension of breadth as strength and weakness, we interviewed 25 prominent permaculture teachers and practitioners across the United States (US) regarding how they define permaculture as a concept and perceive the term’s utility. We find that permaculture casts a wide net that participants grapple with in their own work. They engaged in a negotiation process of how they associate or disassociate themselves with the term, recognizing that it can be both unifying and polarizing. Further, there was noted concern of permaculture’s failure to cite and acknowledge its rootedness in Indigenous knowledge, as well as distinguish itself from Indigenous alternatives. We contextualize these findings within the resounding call for a decolonization of modern ways of living and the science of sustainability, of which permaculture can be critically part of. We conclude with recommended best practices for how to continuously (re-)define permaculture in an embodied and dynamic way to work toward these goals.

The solutions-based design framework of permaculture exhibits transformative potential, working to holistically integrate natural and human systems toward a more just society. The term can be defined and applied in a breadth of ways, contributing to both strengths and weaknesses for its capacity toward change. To explore the tension of breadth as strength and weakness, we interviewed 25 prominent permaculture teachers and practitioners across the United States (US) regarding how they define permaculture as a concept and perceive the term’s utility. We find that permaculture casts a wide net that participants grapple with in their own work. They engaged in a negotiation process of how they associate or disassociate themselves with the term, recognizing that it can be both unifying and polarizing. Further, there was noted concern of permaculture’s failure to cite and acknowledge its rootedness in Indigenous knowledge, as well as distinguish itself from Indigenous alternatives. We contextualize these findings within the resounding call for a decolonization of modern ways of living and the science of sustainability, of which permaculture can be critically part of. We conclude with recommended best practices for how to continuously (re-)define permaculture in an embodied and dynamic way to work toward these goals.

Abstract The growth and development of maize (Zea mays L.) largely depends on its nutrient uptake through the root. Hence, studying its growth, response, and associated metabolic reprogramming to stress conditions is becoming an important research direction. A genome-scale metabolic model (GSM) for the maize root was developed to study its metabolic reprogramming under nitrogen stress conditions. The model was reconstructed based on the available information from KEGG, UniProt, and MaizeCyc. Transcriptomics data derived from the roots of hydroponically grown maize plants were used to incorporate regulatory constraints in the model and simulate nitrogen-non-limiting (N+) and nitrogen-deficient (N−) condition. Model-predicted flux-sum variability analysis achieved 70% accuracy compared with the experimental change of metabolite levels. In addition to predicting important metabolic reprogramming in central carbon, fatty acid, amino acid, and other secondary metabolism, maize root GSM predicted several metabolites (l-methionine, l-asparagine, l-lysine, cholesterol, and l-pipecolate) playing a regulatory role in the root biomass growth. Furthermore, this study revealed eight phosphatidylcholine and phosphatidylglycerol metabolites which, even though not coupled with biomass production, played a key role in the increased biomass production under N-deficient conditions. Overall, the omics-integrated GSM provides a promising tool to facilitate stress condition analysis for maize root and engineer better stress-tolerant maize genotypes.

Abstract The growth and development of maize (Zea mays L.) largely depends on its nutrient uptake through the root. Hence, studying its growth, response, and associated metabolic reprogramming to stress conditions is becoming an important research direction. A genome-scale metabolic model (GSM) for the maize root was developed to study its metabolic reprogramming under nitrogen stress conditions. The model was reconstructed based on the available information from KEGG, UniProt, and MaizeCyc. Transcriptomics data derived from the roots of hydroponically grown maize plants were used to incorporate regulatory constraints in the model and simulate nitrogen-non-limiting (N+) and nitrogen-deficient (N−) condition. Model-predicted flux-sum variability analysis achieved 70% accuracy compared with the experimental change of metabolite levels. In addition to predicting important metabolic reprogramming in central carbon, fatty acid, amino acid, and other secondary metabolism, maize root GSM predicted several metabolites (l-methionine, l-asparagine, l-lysine, cholesterol, and l-pipecolate) playing a regulatory role in the root biomass growth. Furthermore, this study revealed eight phosphatidylcholine and phosphatidylglycerol metabolites which, even though not coupled with biomass production, played a key role in the increased biomass production under N-deficient conditions. Overall, the omics-integrated GSM provides a promising tool to facilitate stress condition analysis for maize root and engineer better stress-tolerant maize genotypes.

The Nigerian government is committed to sustaining rice production to meet national demand. Nevertheless, political tension and climate-induced stressors remain crucial constraints in achieving policy targets. This study examines whether climate change and political instability significantly threaten rice production in Nigeria. First, we employed nonparametric methods to estimate the country's rainfall and temperature trends between 1980Q1 and 2015Q4. Second, we employed the autoregressive distributed lag (ARDL) technique to examine the effects of climate change and political instability on rice production. The results show that while temperature has an increasing pattern, rainfall exhibits no significant trend. The findings from the ARDL estimate reveal that rice production responds negatively to temperature changes but is less sensitive to changes in rainfall. In addition, political instability adversely affects rice production in Nigeria. We argue that Nigeria's slow growth in rice production can be traced back to the impact of climate change and political tension in rice farming areas. As a result, reducing the overall degree of conflict to ensure political stability is critical to boosting the country's self-sufficiency in rice production. We also recommend that farmers be supported and trained to adopt improved rice varieties less prone to extreme climate events while supporting them with irrigation facilities to facilitate rice production.