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Temperature record-breaking events, such as the observed more intense, longer-lasting, and more frequent heat waves, pose a new global challenge to health sectors worldwide. These threats are of particular interest in low-income regions with limited investments in public health and a growing urban population, such as Brazil. Here, we apply a comprehensive interdisciplinary climate-health approach, including meteorological data and a daily mortality record from the Brazilian Health System from 2000 to 2015, covering 21 cities over the Metropolitan Region of Rio de Janeiro. The percentage of absolute mortality increase due to summer extreme temperatures is estimated using a negative binomial regression modeling approach and maximum/minimum temperature-derived indexes as covariates. Moreover, this study assesses the vulnerability to thermal stress for different age groups and both genders and thoroughly analyzes four extremely intense heat waves during 2010 and 2012 regarding their impacts on the population. Results showed that the highest absolute mortality values during heat-related events were linked to circulatory illnesses. However, the highest excess of mortality was related to diabetes, particularly for women within the elderly age groups. Moreover, results indicate that accumulated heat stress conditions during consecutive days preferentially preceded by persistent periods of moderate-temperature, lead to higher excess mortality rather than sporadic single hot days. This work may provide directions in human health policies related to extreme climate events in large tropical metropolitan areas from developing countries, contributing to altering the historically based purely reactive response.

The consumption of plant-based drinks (PBDs) in substitution for cow’s milk (CM) is increasing due to concerns for human and planet health and animal welfare. The present review aims to analyze the main findings from intervention trials investigating the effect of PBDs in comparison with CM on markers of human health. Suitable articles published up to July 2022 were sourced from PubMed and Scopus databases. A total of 29 papers were collected, with 27 focusing on soy drinks (1 of which also evaluated the effects of an almond drink), while only 2 focused on rice drinks. Among studies focused on soy drinks, the most investigated factors were anthropometric parameters (n = 13), the lipid profile (n = 8), markers of inflammation and/or oxidative stress (n = 7), glucose and insulin responses (n = 6) and blood pressure (n = 4). Despite some evidence of a beneficial effect of PBDs, especially for the lipid profile, it was not possible to draw any overall conclusions due to some conflicting results. As well as the low number of studies, a wide heterogeneity was found in terms of the characteristics of subjects, duration and markers, which reduces the strength of the available results. In conclusion, further studies are needed to better elucidate the effects of substituting CM with PBDs, especially in the long term.

Ionic liquid-based aqueous electrolytes with reduced IL content for coupling CO2 capture and electrochemical reduction.

The Coronavirus Disease 2019 (COVID-19) pandemic that spread through the world in 2020 had a major effect on academia. Research projects relying on participatory methods and action research approaches were especially harmed by the restrictions and changes the situation imposed. This study performs a rapid literature review to identify common themes in the narratives of published studies concerning the difficulties of carrying-out participatory research during the COVID-19 pandemic. Perceptions and experiences of the authors of these studies are compiled and summarized. Additionally, insights and lessons learned from two projects in which the authors of this study participated are discussed and used to establish a comparison with the common challenges found in the literature. Over 90% of authors experienced challenges related to digitalization and methodological changes, 70% encountered difficulties with organizational and operational aspects of research, and over 30% felt that personal challenges, as well as issues with participatory aspects of research, were significant. On a positive note, almost 40% of authors from our sample recognize that the pandemic also brought unexpected benefits, such as a reduction in logistical expenses, and the creation of new opportunities for participation. This study adds to the growing body of literature regarding the effects of the COVID-19 pandemic on the research community. Additionally, it comments on the adaptation of participatory action research methods for added sustainability and social inclusion in the face of global crises.

Abstract Social costs derived by fuel poverty are often not considered in policy decision making, leading to the exclusion of vulnerable groups from subsidy and further degradation of old inefficient housing stock. Low-income housing renovation may result in unprofitable under conventional methods due to multiple factors such as the low price of energy of subsidised utility tariffs, the below-average energy consumption, and their inability to invest. This paper analyses policy to public housing retrofitting considering the social costs derived by fuel poverty, a situation of vulnerability driven by a combination of low income and poor living conditions regarding energy consumption and thermal comfort. Enhanced comfort conditions positively affect individuals' health and social life, translating into economic relief for the National Healthcare Service. The search to reduce fuel poverty challenges a paradigm shift in investment in public housing renovation. It could receive additional support from the monetisation of the health benefits derived by building retrofitting. The results of this paper offer local authorities the critical analysis and evaluation framework when it comes to an understanding the policy impact of building retrofit on energy consumption, thermal comfort and health, prioritise the renovations of the public housing stock and adequately allocate public funding.

A 67-year-old Caucasian male with lung cancer was presented to the Emergency Department with asthenia, anorexia, jaundice and choluria. The patient's lung cancer was being treated medically by a combination of paclitaxel/carboplatin with bi-monthly frequency. The patient was also self-medicating with several natural products, including Chlorella (520 mg/day), Silybum marianum (total of 13.5 mg silymarin/day), zinc sulphate (5.5 mg), selenium (50 μg) and 15 g/day of Curcuma longa. In first chemotherapy cycle no toxicity was observed even he was taking other medications as budesonide and sitagliptin. The toxic events started only after the introduction of the dietary products. Chlorella had contamination with cyanobacteria (Oscillatoriales) and 1.08 μg of cyanotoxin Microcystin-LR (MC-LR) per gram of biomass was found. Patient was consuming ca 0.01 μg MC-LR/kg/day. This case report describes the first known case of paclitaxel toxicity probably related to pharmacokinetic interaction with Turmeric and a contaminated Chlorella supplement resulting in an acute toxic hepatitis and the impact on oncologic patient health.

The need for analysis and action across the interrelated domains of human behaviors and lifestyles, environmental sustainability, health and inequality is increasingly apparent. Currently, these areas are often not considered in conjunction when developing policies or interventions, introducing the potential for suboptimal or conflicting outcomes. The INHERIT model has been developed within the EU-funded project INHERIT as a tool to guide thinking and intersectoral action towards changing the behaviors and lifestyles that play such an important role in today’s multidisciplinary challenges. The model integrates ecological public health and behavioral change models, emphasizing inequalities and those parts of the causal process that are influenced by human behaviors and lifestyles. The model was developed through web-based and live discussions with experts and policy stakeholders. To test the model’s usability, the model was applied to aspects of food consumption. This paper shows that the INHERIT model can serve as a tool to identify opportunities for change in important −food-related behaviors and lifestyles and to examine how they impact on health, health inequalities, and the environment in Europe and beyond. The INHERIT model helps clarify these interrelated domains, creating new opportunities to improve environmental health and health inequality, while taking our planetary boundaries into consideration.