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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Leahy, Lily; Scheffers, Brett R.; Andersen, Alan N.; Hirsch, Ben T.; +1 Authors

    Aim: We propose that forest trees create a vertical dimension for ecological niche variation that generates different regimes of climatic exposure, which in turn drives species elevation distributions. We test this hypothesis by statistically modelling the vertical and elevation distributions and microclimate exposure of rainforest ants. Location: Wet Tropics Bioregion, Australia Methods: We conducted 60 ground-to-canopy surveys to determine the vertical (tree) and elevation distributions, and microclimate exposure of ants (101 species) at 15 sites along four mountain ranges. We statistically modelled elevation range size as a function of ant species’ vertical niche breadth and exposure to temperature variance for 55 species found at two or more trees. Results: We found a positive association between vertical niche and elevation range of ant species: for every 3 m increase in vertical niche breadth our models predict a ~150% increase in mean elevation range size. Temperature variance increased with vertical height along the arboreal gradient and ant species exposure to temperature variance explained some of the variation in elevation range size. Main Conclusions: We demonstrate that arboreal ants have broader elevation ranges than ground-dwelling ants and are likely to have increased resilience to climatic variance. The capacity of species to expand their niche by climbing trees could influence their ability to persist over broader elevation ranges. We propose that wherever vertical layering exists - from oceans to forest ecosystems - vertical niche breadth is a potential mechanism driving macrogeographic distribution patterns and resilience to climate change. Data_collections.csv Main survey collections data in a site by species matrix showing all data for all sites surveyed. Tuna baited vials were placed every three metres from ground to canopy in trees at elevation sites at four subregion mountain ranges of the Australian Wet Tropics Bioregion. Note data file includes empty vials that lacked ants. Microclimate_AthertonTemp.csv This file contains Atherton Uplands temperature data from ibuttons deployed at one tree per elevation (200, 400, 600, 800, 1000) at every three metres in height in Dec-Jan 2017- 2018 set to record every half hour. See file Metadata for details of column names and data values.

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    ZENODO
    Dataset . 2021
    License: CC 0
    Data sources: ZENODO
    DRYAD
    Dataset . 2021
    License: CC 0
    Data sources: Datacite
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      ZENODO
      Dataset . 2021
      License: CC 0
      Data sources: ZENODO
      DRYAD
      Dataset . 2021
      License: CC 0
      Data sources: Datacite
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  • Authors: Herzog, Sarah; Louthan, Allison; Kueppers, Lara;

    Demographic data of Sedum lanceolatum under a climate manipulation experiment (heating and watering). Dataset includes one .csv with demographic data for 232 individuals monitored over 2013-2014 which was used, in part, to draw conclusions in "Elevation effects on vital rate sensitivities generate variation in neighbor effects on population growth rate in Sedum lanceolatum" by Herzog et al. (in review). All data was collected under a watering and warming experiment as part of the Alpine Treeline Warming Experiment at Niwot Ridge, Colorado, USA. There are two main data file formats in this archive: comma-separated values (.csv) which can be read using any simple text editor program, such as TextEdit (Mac) and Notepad (Windows). The .pdf data user’s guide can be read using Adobe Acrobat Reader, or any other compatible software.

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    Authors: Ridley, Jeff; Menary, Matthew; Kuhlbrodt, Till; Andrews, Martin; +1 Authors

    Project: Coupled Model Intercomparison Project Phase 6 (CMIP6) datasets - These data have been generated as part of the internationally-coordinated Coupled Model Intercomparison Project Phase 6 (CMIP6; see also GMD Special Issue: http://www.geosci-model-dev.net/special_issue590.html). The simulation data provides a basis for climate research designed to answer fundamental science questions and serves as resource for authors of the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC-AR6). CMIP6 is a project coordinated by the Working Group on Coupled Modelling (WGCM) as part of the World Climate Research Programme (WCRP). Phase 6 builds on previous phases executed under the leadership of the Program for Climate Model Diagnosis and Intercomparison (PCMDI) and relies on the Earth System Grid Federation (ESGF) and the Centre for Environmental Data Analysis (CEDA) along with numerous related activities for implementation. The original data is hosted and partially replicated on a federated collection of data nodes, and most of the data relied on by the IPCC is being archived for long-term preservation at the IPCC Data Distribution Centre (IPCC DDC) hosted by the German Climate Computing Center (DKRZ). The project includes simulations from about 120 global climate models and around 45 institutions and organizations worldwide. Summary: These data include the subset used by IPCC AR6 WGI authors of the datasets originally published in ESGF for 'CMIP6.CMIP.MOHC.HadGEM3-GC31-MM.historical' with the full Data Reference Syntax following the template 'mip_era.activity_id.institution_id.source_id.experiment_id.member_id.table_id.variable_id.grid_label.version'. The HadGEM3-GC3.1-N216ORCA025 climate model, released in 2016, includes the following components: aerosol: UKCA-GLOMAP-mode, atmos: MetUM-HadGEM3-GA7.1 (N216; 432 x 324 longitude/latitude; 85 levels; top level 85 km), land: JULES-HadGEM3-GL7.1, ocean: NEMO-HadGEM3-GO6.0 (eORCA025 tripolar primarily 0.25 deg; 1440 x 1205 longitude/latitude; 75 levels; top grid cell 0-1 m), seaIce: CICE-HadGEM3-GSI8 (eORCA025 tripolar primarily 0.25 deg; 1440 x 1205 longitude/latitude). The model was run by the Met Office Hadley Centre, Fitzroy Road, Exeter, Devon, EX1 3PB, UK (MOHC) in native nominal resolutions: aerosol: 100 km, atmos: 100 km, land: 100 km, ocean: 25 km, seaIce: 25 km.

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    World Data Center for Climate
    Dataset . 2023
    License: CC BY
    Data sources: Datacite
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    World Data Center for Climate
    Dataset . 2023
    License: CC BY
    Data sources: Datacite
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      World Data Center for Climate
      Dataset . 2023
      License: CC BY
      Data sources: Datacite
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      World Data Center for Climate
      Dataset . 2023
      License: CC BY
      Data sources: Datacite
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    Authors: Horton, Tammy; Serpell-Stevens, Amanda; Domedel, Georgina Valls; Bett, Brian James;

    These data record the results of processing otter trawl catches (OTSB14; Merrett & Marshall, 1980) from the National Oceanography Centre (NOC, UK) long-term study of the Porcupine Abyssal Plain (PAP), including the PAP-Sustained Observatory time-series. The data concern catches recovered during the RRS Challenger cruise 135 in 1997. Billett, D.S.M. et al. (1998). RRS Challenger Cruise 135, 15 Oct-30 Oct 1997. BENGAL: High resolution temporal and spatial study of the BENthic biology and Geochemistry of a north-eastern Atlantic abyssal Locality. Southampton Oceanography Centre Cruise Report, No. 19, 49pp.| https://www.bodc.ac.uk/resources/inventories/cruise_inventory/reports/ch135_97.pdf

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    Global Biodiversity Information Facility
    Dataset . 2024
    License: CC BY
    Data sources: Datacite
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      Global Biodiversity Information Facility
      Dataset . 2024
      License: CC BY
      Data sources: Datacite
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    Authors: Hoffmann, Roman; Dimitrova, Anna; Muttarak, Raya; Crespo Cuaresma, Jesus; +1 Authors

    Complete replication data and code for article "A Meta-Analysis of Country Level Studies on Environmental Change and Migration". The rdata file contains both the meta and country level data. The data is also saved separately as xlsx files.

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    Harvard Dataverse
    Dataset . 2020
    License: CC 0
    Data sources: Datacite
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      Harvard Dataverse
      Dataset . 2020
      License: CC 0
      Data sources: Datacite
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    Authors: Myrgiotis, Vasilis; Williams, Mathew;

    Model inputs, model code and aggregated model outputs (seasonal, annual) for every grassland field simulated (2017-2018) in "Myrgiotis et al. The carbon budget of the managed grasslands of Great Britain - informed by earth observations, Biogeosciences, 2022". Input files include (1) climate data (sitecode_M.npy) and (2) satellite based observations of Leaf Area Index (sitecode_O.pkl). Model code written in fortran. Model outputs (i.e. carbon pools, fluxes and balance for 2017 and 2018) aggregated annually (annual_outputs.csv) and monthly (annual_outputs.csv).

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    Edinburgh DataShare
    Dataset . 2022
    License: CC BY
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      Edinburgh DataShare
      Dataset . 2022
      License: CC BY
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    The World Bank Open Data
    Dataset . 2021
    License: CC BY
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      The World Bank Open Data
      Dataset . 2021
      License: CC BY
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    Authors: Stouffer, Ronald;

    Project: Coupled Model Intercomparison Project Phase 6 (CMIP6) datasets - These data have been generated as part of the internationally-coordinated Coupled Model Intercomparison Project Phase 6 (CMIP6; see also GMD Special Issue: http://www.geosci-model-dev.net/special_issue590.html). The simulation data provides a basis for climate research designed to answer fundamental science questions and serves as resource for authors of the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC-AR6). CMIP6 is a project coordinated by the Working Group on Coupled Modelling (WGCM) as part of the World Climate Research Programme (WCRP). Phase 6 builds on previous phases executed under the leadership of the Program for Climate Model Diagnosis and Intercomparison (PCMDI) and relies on the Earth System Grid Federation (ESGF) and the Centre for Environmental Data Analysis (CEDA) along with numerous related activities for implementation. The original data is hosted and partially replicated on a federated collection of data nodes, and most of the data relied on by the IPCC is being archived for long-term preservation at the IPCC Data Distribution Centre (IPCC DDC) hosted by the German Climate Computing Center (DKRZ). The project includes simulations from about 120 global climate models and around 45 institutions and organizations worldwide. Summary: These data include the subset used by IPCC AR6 WGI authors of the datasets originally published in ESGF for 'CMIP6.ScenarioMIP.UA.MCM-UA-1-0' with the full Data Reference Syntax following the template 'mip_era.activity_id.institution_id.source_id.experiment_id.member_id.table_id.variable_id.grid_label.version'. The Manabe Climate Model v1.0 - University of Arizona climate model, released in 1991, includes the following components: aerosol: Modifies surface albedoes (Haywood et al. 1997, doi: 10.1175/1520-0442(1997)010<1562:GCMCOT>2.0.CO;2), atmos: R30L14 (3.75 X 2.5 degree (long-lat) configuration; 96 x 80 longitude/latitude; 14 levels; top level 0.015 sigma, 15 mb), land: Standard Manabe bucket hydrology scheme (Manabe 1969, doi: 10.1175/1520-0493(1969)097<0739:CATOC>2.3.CO;2), landIce: Specified location - invariant in time, has high albedo and latent heat capacity, ocean: MOM1.0 (MOM1, 1.875 X 2.5 deg; 192 x 80 longitude/latitude; 18 levels; top grid cell 0-40 m), seaIce: Thermodynamic ice model (free drift dynamics). The model was run by the Department of Geosciences, University of Arizona, Tucson, AZ 85721, USA (UA) in native nominal resolutions: aerosol: 250 km, atmos: 250 km, land: 250 km, landIce: 250 km, ocean: 250 km, seaIce: 250 km.

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    World Data Center for Climate
    Dataset . 2023
    License: CC BY
    Data sources: Datacite
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      World Data Center for Climate
      Dataset . 2023
      License: CC BY
      Data sources: Datacite
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    Obesity continues to be a prevalent health concern affecting every race of the American population. According to data from the World Health Organization, 54% of U.S. adults are overweight (body mass index (BMI) >25 kg/m2 ) and 22% are obese (BMI >30 kg/m2) (1). In addition, 25% of U.S. children are overweight or obese (1). Studies show that obese children are likely to become obese adults (2-5). Also, recent studies report significant years of life lost due to the impact of being an obese adult (6, 7). Thus, insights into the pathogenesis of childhood obesity and preventative measures are needed to combat the inevitable increase in worldwide incidence of obesity and its associated co-morbidities. Recent studies have identified a new gastroenteric hormone, ghrelin, as a long-term regulator of energy balance in humans (12). Ghrelin is a 28 amino acid acylated peptide which is an endogenous ligand of the growth hormone secretagogue receptor (GHS-R), a hypothalamic G-protein-coupled receptor (13). Enteroendocrine cells (X/A-like cells) of the stomach are the major site of ghrelin synthesis, although a minor proportion of ghrelin synthesis occurs in other sites such as the hypothalamus, pituitary, duodenum, jejunum and lung (14) (15, 16). The hypothesis that hyperghrelinemia causes some of the features of PWS predicts that this disorder will be ameliorated (partially or completely) by lowering ghrelin levels. We have recently shown that the somatostatin agonist, octreotide, suppresses ghrelin levels in humans. If octreotide remains effective in longer term studies, the drug may become an adjuvant therapy, in addition to growth hormone, to control the insatiable appetite and morbid obesity seen in this condition. The purpose of this study is to investigate over a 6 month period the effect of octreotide therapy on food intake, sense of hunger, body weight, body composition, efficiency of burning calories, biomarkers of weight regulation and growth hormone markers in children and young Adults with Prader-Willi Syndrome(PWS).

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    ClinicalTrials.gov
    Clinical Trial . 2006
    Data sources: ClinicalTrials.gov
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      ClinicalTrials.gov
      Clinical Trial . 2006
      Data sources: ClinicalTrials.gov
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    Authors: Fosas, Daniel; Nikolaidou, Elli; Roberts, Matt; Allen, Stephen; +2 Authors

    Dataset for the journal paper "Towards Active Buildings: rating grid-servicing buildings", which describes the simulations for the 20 case study buildings. The simulation inputs describe the intended characteristics as part of the early design stage process, and the outputs the performance metrics under the rating system introduced in the journal paper, called the ABCode1. Such outputs rate the relative merits of each case study in terms of embodied carbon, energy requirements, energy generation and energy flexibility. The simulation outputs have been generated using the inputs included in the dataset, which were then simulated in David Coley’s ZEBRA and then evaluated with the rating system proposed in the journal publication as part of ABCode1. The files are in the original Excel xlsx file (Microsoft Office 365), but it may be viewed by any other spread sheet tools such as LibreOffice's Calc.

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    University of Bath Research Data Archive
    Dataset . 2020
    License: CC BY
    Data sources: Datacite
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      University of Bath Research Data Archive
      Dataset . 2020
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    Authors: Leahy, Lily; Scheffers, Brett R.; Andersen, Alan N.; Hirsch, Ben T.; +1 Authors

    Aim: We propose that forest trees create a vertical dimension for ecological niche variation that generates different regimes of climatic exposure, which in turn drives species elevation distributions. We test this hypothesis by statistically modelling the vertical and elevation distributions and microclimate exposure of rainforest ants. Location: Wet Tropics Bioregion, Australia Methods: We conducted 60 ground-to-canopy surveys to determine the vertical (tree) and elevation distributions, and microclimate exposure of ants (101 species) at 15 sites along four mountain ranges. We statistically modelled elevation range size as a function of ant species’ vertical niche breadth and exposure to temperature variance for 55 species found at two or more trees. Results: We found a positive association between vertical niche and elevation range of ant species: for every 3 m increase in vertical niche breadth our models predict a ~150% increase in mean elevation range size. Temperature variance increased with vertical height along the arboreal gradient and ant species exposure to temperature variance explained some of the variation in elevation range size. Main Conclusions: We demonstrate that arboreal ants have broader elevation ranges than ground-dwelling ants and are likely to have increased resilience to climatic variance. The capacity of species to expand their niche by climbing trees could influence their ability to persist over broader elevation ranges. We propose that wherever vertical layering exists - from oceans to forest ecosystems - vertical niche breadth is a potential mechanism driving macrogeographic distribution patterns and resilience to climate change. Data_collections.csv Main survey collections data in a site by species matrix showing all data for all sites surveyed. Tuna baited vials were placed every three metres from ground to canopy in trees at elevation sites at four subregion mountain ranges of the Australian Wet Tropics Bioregion. Note data file includes empty vials that lacked ants. Microclimate_AthertonTemp.csv This file contains Atherton Uplands temperature data from ibuttons deployed at one tree per elevation (200, 400, 600, 800, 1000) at every three metres in height in Dec-Jan 2017- 2018 set to record every half hour. See file Metadata for details of column names and data values.

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    ZENODO
    Dataset . 2021
    License: CC 0
    Data sources: ZENODO
    DRYAD
    Dataset . 2021
    License: CC 0
    Data sources: Datacite
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      ZENODO
      Dataset . 2021
      License: CC 0
      Data sources: ZENODO
      DRYAD
      Dataset . 2021
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  • Authors: Herzog, Sarah; Louthan, Allison; Kueppers, Lara;

    Demographic data of Sedum lanceolatum under a climate manipulation experiment (heating and watering). Dataset includes one .csv with demographic data for 232 individuals monitored over 2013-2014 which was used, in part, to draw conclusions in "Elevation effects on vital rate sensitivities generate variation in neighbor effects on population growth rate in Sedum lanceolatum" by Herzog et al. (in review). All data was collected under a watering and warming experiment as part of the Alpine Treeline Warming Experiment at Niwot Ridge, Colorado, USA. There are two main data file formats in this archive: comma-separated values (.csv) which can be read using any simple text editor program, such as TextEdit (Mac) and Notepad (Windows). The .pdf data user’s guide can be read using Adobe Acrobat Reader, or any other compatible software.

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    Authors: Ridley, Jeff; Menary, Matthew; Kuhlbrodt, Till; Andrews, Martin; +1 Authors

    Project: Coupled Model Intercomparison Project Phase 6 (CMIP6) datasets - These data have been generated as part of the internationally-coordinated Coupled Model Intercomparison Project Phase 6 (CMIP6; see also GMD Special Issue: http://www.geosci-model-dev.net/special_issue590.html). The simulation data provides a basis for climate research designed to answer fundamental science questions and serves as resource for authors of the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC-AR6). CMIP6 is a project coordinated by the Working Group on Coupled Modelling (WGCM) as part of the World Climate Research Programme (WCRP). Phase 6 builds on previous phases executed under the leadership of the Program for Climate Model Diagnosis and Intercomparison (PCMDI) and relies on the Earth System Grid Federation (ESGF) and the Centre for Environmental Data Analysis (CEDA) along with numerous related activities for implementation. The original data is hosted and partially replicated on a federated collection of data nodes, and most of the data relied on by the IPCC is being archived for long-term preservation at the IPCC Data Distribution Centre (IPCC DDC) hosted by the German Climate Computing Center (DKRZ). The project includes simulations from about 120 global climate models and around 45 institutions and organizations worldwide. Summary: These data include the subset used by IPCC AR6 WGI authors of the datasets originally published in ESGF for 'CMIP6.CMIP.MOHC.HadGEM3-GC31-MM.historical' with the full Data Reference Syntax following the template 'mip_era.activity_id.institution_id.source_id.experiment_id.member_id.table_id.variable_id.grid_label.version'. The HadGEM3-GC3.1-N216ORCA025 climate model, released in 2016, includes the following components: aerosol: UKCA-GLOMAP-mode, atmos: MetUM-HadGEM3-GA7.1 (N216; 432 x 324 longitude/latitude; 85 levels; top level 85 km), land: JULES-HadGEM3-GL7.1, ocean: NEMO-HadGEM3-GO6.0 (eORCA025 tripolar primarily 0.25 deg; 1440 x 1205 longitude/latitude; 75 levels; top grid cell 0-1 m), seaIce: CICE-HadGEM3-GSI8 (eORCA025 tripolar primarily 0.25 deg; 1440 x 1205 longitude/latitude). The model was run by the Met Office Hadley Centre, Fitzroy Road, Exeter, Devon, EX1 3PB, UK (MOHC) in native nominal resolutions: aerosol: 100 km, atmos: 100 km, land: 100 km, ocean: 25 km, seaIce: 25 km.

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    World Data Center for Climate
    Dataset . 2023
    License: CC BY
    Data sources: Datacite
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    World Data Center for Climate
    Dataset . 2023
    License: CC BY
    Data sources: Datacite
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      World Data Center for Climate
      Dataset . 2023
      License: CC BY
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      World Data Center for Climate
      Dataset . 2023
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    Authors: Horton, Tammy; Serpell-Stevens, Amanda; Domedel, Georgina Valls; Bett, Brian James;

    These data record the results of processing otter trawl catches (OTSB14; Merrett & Marshall, 1980) from the National Oceanography Centre (NOC, UK) long-term study of the Porcupine Abyssal Plain (PAP), including the PAP-Sustained Observatory time-series. The data concern catches recovered during the RRS Challenger cruise 135 in 1997. Billett, D.S.M. et al. (1998). RRS Challenger Cruise 135, 15 Oct-30 Oct 1997. BENGAL: High resolution temporal and spatial study of the BENthic biology and Geochemistry of a north-eastern Atlantic abyssal Locality. Southampton Oceanography Centre Cruise Report, No. 19, 49pp.| https://www.bodc.ac.uk/resources/inventories/cruise_inventory/reports/ch135_97.pdf

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    Global Biodiversity Information Facility
    Dataset . 2024
    License: CC BY
    Data sources: Datacite
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      Global Biodiversity Information Facility
      Dataset . 2024
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    Authors: Hoffmann, Roman; Dimitrova, Anna; Muttarak, Raya; Crespo Cuaresma, Jesus; +1 Authors

    Complete replication data and code for article "A Meta-Analysis of Country Level Studies on Environmental Change and Migration". The rdata file contains both the meta and country level data. The data is also saved separately as xlsx files.

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    Harvard Dataverse
    Dataset . 2020
    License: CC 0
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      Dataset . 2020
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    Authors: Myrgiotis, Vasilis; Williams, Mathew;

    Model inputs, model code and aggregated model outputs (seasonal, annual) for every grassland field simulated (2017-2018) in "Myrgiotis et al. The carbon budget of the managed grasslands of Great Britain - informed by earth observations, Biogeosciences, 2022". Input files include (1) climate data (sitecode_M.npy) and (2) satellite based observations of Leaf Area Index (sitecode_O.pkl). Model code written in fortran. Model outputs (i.e. carbon pools, fluxes and balance for 2017 and 2018) aggregated annually (annual_outputs.csv) and monthly (annual_outputs.csv).

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    Edinburgh DataShare
    Dataset . 2022
    License: CC BY
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      Edinburgh DataShare
      Dataset . 2022
      License: CC BY
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    The World Bank Open Data
    Dataset . 2021
    License: CC BY
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      The World Bank Open Data
      Dataset . 2021
      License: CC BY
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    Authors: Stouffer, Ronald;

    Project: Coupled Model Intercomparison Project Phase 6 (CMIP6) datasets - These data have been generated as part of the internationally-coordinated Coupled Model Intercomparison Project Phase 6 (CMIP6; see also GMD Special Issue: http://www.geosci-model-dev.net/special_issue590.html). The simulation data provides a basis for climate research designed to answer fundamental science questions and serves as resource for authors of the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC-AR6). CMIP6 is a project coordinated by the Working Group on Coupled Modelling (WGCM) as part of the World Climate Research Programme (WCRP). Phase 6 builds on previous phases executed under the leadership of the Program for Climate Model Diagnosis and Intercomparison (PCMDI) and relies on the Earth System Grid Federation (ESGF) and the Centre for Environmental Data Analysis (CEDA) along with numerous related activities for implementation. The original data is hosted and partially replicated on a federated collection of data nodes, and most of the data relied on by the IPCC is being archived for long-term preservation at the IPCC Data Distribution Centre (IPCC DDC) hosted by the German Climate Computing Center (DKRZ). The project includes simulations from about 120 global climate models and around 45 institutions and organizations worldwide. Summary: These data include the subset used by IPCC AR6 WGI authors of the datasets originally published in ESGF for 'CMIP6.ScenarioMIP.UA.MCM-UA-1-0' with the full Data Reference Syntax following the template 'mip_era.activity_id.institution_id.source_id.experiment_id.member_id.table_id.variable_id.grid_label.version'. The Manabe Climate Model v1.0 - University of Arizona climate model, released in 1991, includes the following components: aerosol: Modifies surface albedoes (Haywood et al. 1997, doi: 10.1175/1520-0442(1997)010<1562:GCMCOT>2.0.CO;2), atmos: R30L14 (3.75 X 2.5 degree (long-lat) configuration; 96 x 80 longitude/latitude; 14 levels; top level 0.015 sigma, 15 mb), land: Standard Manabe bucket hydrology scheme (Manabe 1969, doi: 10.1175/1520-0493(1969)097<0739:CATOC>2.3.CO;2), landIce: Specified location - invariant in time, has high albedo and latent heat capacity, ocean: MOM1.0 (MOM1, 1.875 X 2.5 deg; 192 x 80 longitude/latitude; 18 levels; top grid cell 0-40 m), seaIce: Thermodynamic ice model (free drift dynamics). The model was run by the Department of Geosciences, University of Arizona, Tucson, AZ 85721, USA (UA) in native nominal resolutions: aerosol: 250 km, atmos: 250 km, land: 250 km, landIce: 250 km, ocean: 250 km, seaIce: 250 km.

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    World Data Center for Climate
    Dataset . 2023
    License: CC BY
    Data sources: Datacite
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      World Data Center for Climate
      Dataset . 2023
      License: CC BY
      Data sources: Datacite
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    Obesity continues to be a prevalent health concern affecting every race of the American population. According to data from the World Health Organization, 54% of U.S. adults are overweight (body mass index (BMI) >25 kg/m2 ) and 22% are obese (BMI >30 kg/m2) (1). In addition, 25% of U.S. children are overweight or obese (1). Studies show that obese children are likely to become obese adults (2-5). Also, recent studies report significant years of life lost due to the impact of being an obese adult (6, 7). Thus, insights into the pathogenesis of childhood obesity and preventative measures are needed to combat the inevitable increase in worldwide incidence of obesity and its associated co-morbidities. Recent studies have identified a new gastroenteric hormone, ghrelin, as a long-term regulator of energy balance in humans (12). Ghrelin is a 28 amino acid acylated peptide which is an endogenous ligand of the growth hormone secretagogue receptor (GHS-R), a hypothalamic G-protein-coupled receptor (13). Enteroendocrine cells (X/A-like cells) of the stomach are the major site of ghrelin synthesis, although a minor proportion of ghrelin synthesis occurs in other sites such as the hypothalamus, pituitary, duodenum, jejunum and lung (14) (15, 16). The hypothesis that hyperghrelinemia causes some of the features of PWS predicts that this disorder will be ameliorated (partially or completely) by lowering ghrelin levels. We have recently shown that the somatostatin agonist, octreotide, suppresses ghrelin levels in humans. If octreotide remains effective in longer term studies, the drug may become an adjuvant therapy, in addition to growth hormone, to control the insatiable appetite and morbid obesity seen in this condition. The purpose of this study is to investigate over a 6 month period the effect of octreotide therapy on food intake, sense of hunger, body weight, body composition, efficiency of burning calories, biomarkers of weight regulation and growth hormone markers in children and young Adults with Prader-Willi Syndrome(PWS).

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    ClinicalTrials.gov
    Clinical Trial . 2006
    Data sources: ClinicalTrials.gov
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      ClinicalTrials.gov
      Clinical Trial . 2006
      Data sources: ClinicalTrials.gov
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    Authors: Fosas, Daniel; Nikolaidou, Elli; Roberts, Matt; Allen, Stephen; +2 Authors

    Dataset for the journal paper "Towards Active Buildings: rating grid-servicing buildings", which describes the simulations for the 20 case study buildings. The simulation inputs describe the intended characteristics as part of the early design stage process, and the outputs the performance metrics under the rating system introduced in the journal paper, called the ABCode1. Such outputs rate the relative merits of each case study in terms of embodied carbon, energy requirements, energy generation and energy flexibility. The simulation outputs have been generated using the inputs included in the dataset, which were then simulated in David Coley’s ZEBRA and then evaluated with the rating system proposed in the journal publication as part of ABCode1. The files are in the original Excel xlsx file (Microsoft Office 365), but it may be viewed by any other spread sheet tools such as LibreOffice's Calc.

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    University of Bath Research Data Archive
    Dataset . 2020
    License: CC BY
    Data sources: Datacite
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      University of Bath Research Data Archive
      Dataset . 2020
      License: CC BY
      Data sources: Datacite
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