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In public health terms, alcohol is no ordinary commodity. It accounts not only for a substantial portion of the world’s burden of disease but also for much social harm. Because of this, a majority of countries have some kind of restrictions beyond general rules for foodstuffs on alcohol’s availability and promotion. On the international level, however, restrictions in the interests of public health are minimal. On the contrary, indeed, international and regional trade agreements are increasingly restricting what national governments can do to control the alcohol market.

AbstractScientifically rigorous guidance to policy makers on mitigation options for meeting the Paris Agreement long-term temperature goal requires an evaluation of long-term global-warming implications of greenhouse gas emissions pathways. Here we employ a uniform and transparent methodology to evaluate Paris Agreement compatibility of influential institutional emission scenarios from the grey literature, including those from Shell, BP, and the International Energy Agency. We compare a selection of these scenarios analysed with this methodology to the Integrated Assessment Model scenarios assessed by the Intergovernmental Panel on Climate Change. We harmonize emissions to a consistent base-year and account for all greenhouse gases and aerosol precursor emissions, ensuring a self-consistent comparison of climate variables. An evaluation of peak and end-of-century temperatures is made, with both being relevant to the Paris Agreement goal. Of the scenarios assessed, we find that only the IEA Net Zero 2050 scenario is aligned with the criteria for Paris Agreement consistency employed here. We investigate root causes for misalignment with these criteria based on the underlying energy system transformation.

Abstract. Evidence contained within historical documents and inscriptions provides an important record of climate variability for periods prior to the onset of systematic meteorological data collection. A common approach used by historical climatologists to convert such qualitative documentary evidence into continuous quantitative proxy data is through the generation of ordinal-scale climate indices. There is, however, considerable variability in the types of phenomena reconstructed using an index approach and the practice of index development in different parts of the world. This review, written by members of the PAGES CRIAS Working Group – a collective of climate historians and historical climatologists researching Climate Reconstructions and Impacts from the Archives of Societies – provides the first global synthesis of the use of the index approach in climate reconstruction. We begin by summarising the range of studies that have used indices for climate reconstruction across six continents (Europe, Asia, Africa, the Americas, Australia) plus the world's oceans. We then outline the different methods by which indices are developed in each of these regions, including a discussion of the processes adopted to verify and calibrate index series, and the measures used to express confidence and uncertainty. We conclude with a series of recommendations to guide the development of future index-based climate reconstructions to maximise their effectiveness for use by climate modellers and in multiproxy climate reconstructions.

This paper investigates the concern that green buildings may promote energy efficiency and other aspects of sustainability, but not necessarily the health and well-being of occupants through better indoor air quality (IAQ). We ask ten questions to explore IAQ challenges for green buildings as well as opportunities to improve IAQ within green buildings and their programs. Our focus is on IAQ, while recognizing that many factors influence human health and the healthfulness of a building. We begin with an overview of green buildings, IAQ, and whether and how green building certifications address IAQ. Next, we examine evidence on whether green buildings have better IAQ than comparable conventional buildings. Then, we identify so-called green practices and green products that can have unintended and unfavorable effects on IAQ. Looking ahead, we offer both immediate and longer-term actions, and a set of research questions, that can help green buildings to more effectively promote IAQ. This article supports a growing recognition of the importance of IAQ in green buildings, and the opportunities for improvements. As the World Green Building Council [95] and others have emphasized, people are the most valuable asset of organizations, and efforts to improve IAQ can improve health, well-being, productivity, and profitability.

AbstractSpatial responses of species to past climate change depend on both intrinsic traits (climatic niche breadth, dispersal rates) and the scale of climatic fluctuations across the landscape. New capabilities in generating and analysing population genomic data, along with spatial modelling, have unleashed our capacity to infer how past climate changes have shaped populations, and by extension, complex communities. Combining these approaches, we uncover lineage diversity across four codistributed lizards from the Australian Monsoonal Tropics and explore how varying climatic tolerances interact with regional climate history to generate common vs. disparate responses to late Pleistocene change. We find more divergent spatial structuring and temporal demographic responses in the drier Kimberley region compared to the more mesic and consistently suitable Top End. We hypothesize that, in general, the effects of species’ traits on sensitivity to climate fluctuation will be more evident in climatically marginal regions. If true, this points to the need in climatically marginal areas to craft more species‐(or trait)‐specific strategies for persistence under future climate change.

Abstract Grazing land models can assess the provisioning and trade-offs among ecosystem services attributable to grazing management strategies. We reviewed 12 grazing land models used for evaluating forage and animal (meat and milk) production, soil C sequestration, greenhouse gas emission, and nitrogen leaching, under both current and projected climate conditions. Given the spatial and temporal variability that characterizes most rangelands and pastures in which animal, plant, and soil interact, none of the models currently have the capability to simulate a full suite of ecosystem services provided by grazing lands at different spatial scales and across multiple locations. A large number of model applications have focused on topics such as environmental impacts of grazing land management and sustainability of ecosystems. Additional model components are needed to address the spatial and temporal dynamics of animal foraging behavior and interactions with biophysical and ecological processes on grazing lands and their impacts on animal performance. In addition to identified knowledge gaps in simulating biophysical processes in grazing land ecosystems, our review suggests further improvements that could increase adoption of these models as decision support tools. Grazing land models need to increase user-friendliness by utilizing available big data to minimize model parameterization so that multiple models can be used to reduce simulation uncertainty. Efforts need to reduce inconsistencies among grazing land models in simulated ecosystem services and grazing management effects by carefully examining the underlying biophysical and ecological processes and their interactions in each model. Learning experiences among modelers, experimentalists, and stakeholders need to be strengthened by co-developing modeling objectives, approaches, and interpretation of simulation results.

While microbial activities in environmental systems play a key role in the utilization and cycling of essential elements and compounds, microbial activity and growth frequently fluctuates in response to environmental stimuli and perturbations. To investigate these fluctuations within a saturated aquifer system, we monitored a carbon-stimulated in situ Geobacter population while iron reduction was occurring, using 16S rRNA abundances and high-resolution tandem mass spectrometry proteome measurements. Following carbon amendment, 16S rRNA analysis of temporally separated samples revealed the rapid enrichment of Geobacter-like environmental strains with strong similarity to G. bemidjiensis. Tandem mass spectrometry proteomics measurements suggest high carbon flux through Geobacter respiratory pathways, and the synthesis of anapleurotic four carbon compounds from acetyl-CoA via pyruvate ferredoxin oxidoreductase activity. Across a 40-day period where Fe(III) reduction was occurring, fluctuations in protein expression reflected changes in anabolic versus catabolic reactions, with increased levels of biosynthesis occurring soon after acetate arrival in the aquifer. In addition, localized shifts in nutrient limitation were inferred based on expression of nitrogenase enzymes and phosphate uptake proteins. These temporal data offer the first example of differing microbial protein expression associated with changing geochemical conditions in a subsurface environment.