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In the transition from linear production systems, unsustainable from the point of view of resources, to a model that finds strength in environmental, social and economic sustainability, the circular economy paradigm is the foundation that facilitates the planetary agro-ecological transition. The European Union has taken a number of steps (including the Circular Economy Package of Directives) shaping circularity as a wide-ranging driver measure involving many sectors. The paper intends to provide a regulatory framework on the current general situation regarding circularity in European Union, in order to extrapolate and give evidence to the aspects that intersect the agri-food sector. This is not only because they are poorly addressed in the literature, but also because there is a lack of regulatory instruments on the circular economy specifically addressing this area of interest. For this purpose, the analysis focuses on waste and residue/scrap management issues, recognized by law as by-products and end-of-waste status, as they are covered by circular economy legislation and as they can be applied to the agri-food sector. The latter allow the implementation of circularity strategies in the agri-food sector and, given the numerousness of production chains and the peculiarities of each of them, various regeneration and/or reuse processes of specific resources may be depicted. The intent is to provide useful knowledge on how to implement sustainable waste management, also proposing a concrete case on a by-product of olive oil processing, through which it is possible to highlight how the correct application of regulations favors the adoption of circular economic and management models in the firms involved, as well as informing the relevant economic operators on the possible profiles of legal liability that may arise from insufficient knowledge. Furthermore, this paper delves into the European Green Deal’s Strategy as it enriches the circular economy paradigm with new facets. NextGenerationEU and the National Recovery and Resilience Plan financially support this strategy in the aftermath of the socioeconomic crisis from COVID-19 in the EU Member States. This is in order to achieve the objective of achieving the agro-ecological transition.

Assessing ambitious nature conservation strategies in a below 2 degrees warmer and food-secure world – supplementary spatial data Authors: Marcel Kok, Johan Meijer, Willem-Jan van Zeist, Jelle Hilbers, Marco Immovilli, Jan Janse, Elke Stehfest, Michel Bakkenes, Andrzej Tabeau, Aafke Schipper, Rob Alkemade Point of contact: Marcel.Kok@pbl.nl Research paper summary: Global biodiversity is projected to further decline under a wide range of future socio-economic development pathways, even in sustainability-oriented scenarios. This raises the question how biodiversity can be put on a path to recovery, the core challenge for the CBD post-2020 global biodiversity framework. We designed two contrasting, ambitious global conservation strategies, ‘Half Earth’ (HE) and ‘Sharing the Planet’ (SP), and evaluated their ability to restore terrestrial and freshwater biodiversity and to provide nature’s contributions to people (NCP), while also limiting global warming below 2 degrees and ensuring food security. We applied the integrated assessment framework IMAGE with the GLOBIO biodiversity model, using the ‘Middle of the Road’ Shared Socio-economic Pathway (SSP2) with its projected human population growth as baseline. We found that both conservation strategies reduce the global loss of biodiversity and NCP, but are insufficient to restore biodiversity. The HE strategy performs generally better for terrestrial biodiversity (biodiversity intactness (MSA), Area of Habitat Index, Living Planet Index, Red List Index) in currently still natural regions. The SP strategy yields more improvements for biodiversity in human-used areas, aquatic biodiversity and for regulating NCP (pest control, pollination, erosion control, water quality). However, the ‘conservation only’ scenarios show a considerable increase in food security risks and further global temperature increase, compared to the baseline. To restore biodiversity, it is necessary to combine conservation strategies with a portfolio of ‘integrated sustainability measures’ including climate change mitigation actions to change the energy and food systems, where minimizing food wastes and reducing consumption of animal products are crucial. The combination of conservation strategies and additional sustainability measures will restore biodiversity an NCP while keeping global warming below two degrees and food security risks below the baseline projection. Contents: This repository contains the supplementary spatial data describing the specific prioritization of conservation areas under the Half Earth (HE) and Sharing the Planet (SP) scenarios, and the resulting scenario land use and MSA data sets for the year 2050, including also a baseline (BL) scenario. All spatial data is in geotiff format at a 10 arcsecond resolution in WGS84 coordinate system. Detailed description of the methodology is provided in the paper listed under "related identifiers". Keywords: Nature conservation, Half Earth, Sharing the Planet, Climate Change, Food Security, Solution-oriented scenarios, Biodiversity, Nature’s Contribution to People, NCP This repository contains the supplementary spatial data describing the specific prioritization of conservation areas under the Half Earth (HE) and Sharing the Planet (SP) scenarios, and the resulting scenario land use and MSA data sets for the year 2050, including also a baseline (BL) scenario. All spatial data is in geotiff format at a 10 arcsecond resolution in WGS84 coordinate system. Detailed description of the methodology is provided in the paper listed under "related identifiers".

1. Natural populations deliver a wide range of products that provide income for millions of people and need to be exploited sustainably. Large heterogeneity in individual performance within these exploited populations has the potential to improve population recovery after exploitation and thus help sustaining yields over time. 2. We explored the potential of using individual heterogeneity to design smarter harvest schemes, by sparing individuals that contribute most to future productivity and population growth, using the understorey palm Chamaedorea elegans as a model system. Leaves of this palm are an important non-timber forest product and long-term inter-individual growth variability can be evaluated from internode lengths. 3. We studied a population of 830 individuals, half of which was subjected to a 67 % defoliation treatment for three years. We measured effects of defoliation on vital rates and leaf size – a trait that determines marketability. We constructed integral projection models in which vital rates depended on stem length, past growth rate, and defoliation, and evaluated transient population dynamics to quantify population development and leaf yield. We then simulated scenarios in which we spared individuals that were either most important for population growth or had leaves smaller than marketable size. 4. Individuals varying in size or past growth rate responded similarly to leaf harvesting in terms of growth and reproduction. By contrast, defoliation-induced reduction in survival chance was smaller in large individuals than in small ones. Simulations showed that harvest-induced population decline was much reduced when individuals from size and past growth classes that contributed most to population growth were spared. Under this scenario cumulative leaf harvest over 20 years was somewhat reduced, but long-term leaf production was sustained. A three-fold increase in leaf yield was generated when individuals with small leaves are spared. 5. Synthesis and applications This study demonstrates the potential to create smarter systems of palm leaf harvest by accounting for individual heterogeneity within exploited populations. Sparing individuals that contribute most to population growth ensured sustained leaf production over time. The concepts and methods presented here are generally applicable to exploited plant and animal species which exhibit considerable individual heterogeneity. Vital rate and internode dataThis data file contains annual vital rate data (stem length growth, fruit production, survival and leaf production) of 830 individuals of the understorey palm Chamaedorea elegans, collected in a 0.7 ha plot in Chiapas, Mexico, during the period November 2012 - November 2015. A 2/3 defoliation treatment was repeatedly applied to half of the individuals. The data file also contains measurements of the lengths of all internodes of all individuals.

Solar energy, since it is available every day, is seen as one of the most valuable renewable energy resources. Thus, the energy of sun should be efficiently used in various applications. The most known applications that use solar energy are heating water and spaces. High efficiency solar collectors need appropriate selective surfaces to absorb the heat. Selective surfaces (Selektif-Sera) used in this study are applied to flat collectors, which are produced by a roll to roll cost effective coating of nano nickel layers, developed in Selektif Teknoloji Co. Inc. Efficiency of flat collectors using Selektif-Sera absorbers are calculated in collaboration with Institute for Solar Technik Rapperswil, Switzerland. The main cause of high energy consumption in industry is mostly caused from low temperature level processes. There is considerable effort in research to minimize the energy use by renewable energy sources such as solar energy. A feasibility study will be presented to obtain the potential of solar thermal energy utilization in the textile industry using these solar collectors. For the feasibility calculations presented in this study, textile dyeing and finishing factory located at Kahramanmaras is selected since the geographic location was an important factor. Kahramanmaras is located in the south east part of Turkey thus has a great potential to have solar illumination much longer. It was observed that, the collector area is limited by the available area in the factory, thus a hybrid heating generating system (lignite/solar thermal) was preferred in the calculations of this study to be more realistic. During the feasibility work, the calculations took into account the preheating process, where well waters heated from 15 °C to 30-40 °C by using the hot waters in heat exchangers. Then the preheated water was heated again by high efficiency solar collectors. Economic comparison between the lignite use and solar thermal collector use was provided to determine the optimal system that can be used efficiently. The optimum design of solar thermal systems was studied depending on the optimum collector area. It was found that the solar thermal system is more economic and efficient than the merely lignite use. Return on investment time is calculated as 5.15 years. {"references": ["http://www.aee-intec.at/0uploads/dateien561.pdf, Accessed on 18/05/2016.", "http://www.solarthermalworld.org/sites/gstec/files/SoPro_Leaflet_en.pdfAccessed on 18/05/2016.", "Kalogirou S. \"The potential of solar industrial process heat applications\", Applied Energy, 2003, vol. 76, no. 4, pp. 337-361.", "S Mekhilef, R Saidur, A Safari, \"A review on solar energy use in industries\", Renewable and Sustainable Energy, 2011, vol. 15, no. 4 pp. 1777-1790.", "Taibi, E, Gielen D, Bazilian M. \"Measuring energy poverty: Focusing on what matters\", Renewable and Sustainable Energy, 2012, vol.16, no.1, pp. 735-744", "Faninger, G., \"The potential of Solar Heat in the future energy system\", IFF-University of Klagenfurt, Austria; www.uni-klu.ac.at/iff/ikn/downloads/Potential_of_Solar_Heat.pdf, Accessed on 18/05/2016", "Vannoni, C., Battisti, R., Drigo, S., Potential for Solar Heat in Industrial Processes, Task 33, 2008. Solar Cooling and Heating Committee of the International Energy Agency (IEA).", "TMMOB Mechanical Engineering Chamber Report, \"T\u00fcrkiye'nin Enerji G\u00f6r\u00fcn\u00fcm\u00fc\", 2012, pp. 1588", "Kad\u0131rgan F., Roll to roll manufacturing of solar selective sheets, PCT patent, PCT/IB2010/055006, WO/2012/059789 \n[10]\thttp://www.estif.org/fileadmin/estif/content/policies/downloads/D23-solar-industrial-process-heat.pdf, Accessed on 20/05/2016"]}

Description of the four files: contacts.xlsx List of detected contacts for the three case studies pymol_files_case_study_1.zip Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 1: comparison between contacts of myoglobin against hemoglobin pymol_files_case_study_2.zip Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 2: comparison between contacts of RBDs of SARS-CoV-1 vs. SARS-CoV-2 both complexed with the cell receptor ACE2 pymol_files_case_study_3.zip Contains files in PDB format of the analyzed structures, and files in PML format used to display visualizations in the PyMOL tool for the case study 3: comparison between contacts of glucose-tolerant vs. non-tolerant β-glucosidases

Objectives: To evaluate (1) the state of the art in sustainability research and (2) the outcomes of professionals’ adherence to guideline recommendations in medical practice. Design: Systematic review. Data sources: Searches were conducted until August 2015 in MEDLINE, CINAHL, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL) and the Guidelines International Network (GIN) library. A snowball strategy, in which reference sections of other reviews and of included papers were searched, was used to identify additional papers. Eligibility criteria: Studies needed to be focused on sustainability and on professionals’ adherence to clinical practice guidelines in medical care. Studies had to include at least 2 measurements: 1 before (PRE) or immediately after implementation (EARLY POST) and 1 measurement longer than 1 year after active implementation (LATE POST). Results: The search retrieved 4219 items, of which 14 studies met the inclusion criteria, involving 18 sustainability evaluations. The mean timeframe between the end of active implementation and the sustainability evaluation was 2.6 years (minimum 1.5–maximum 7.0). The studies were heterogeneous with respect to their methodology. Sustainability was considered to be successful if performance in terms of professionals’ adherence was fully maintained in the late postimplementation phase. Long-term sustainability of professionals’ adherence was reported in 7 out of 18 evaluations, adherence was not sustained in 6 evaluations, 4 evaluations showed mixed sustainability results and in 1 evaluation it was unclear whether the professional adherence was sustained. Conclusions: (2) Professionals’ adherence to a clinical practice guideline in medical care decreased after more than 1 year after implementation in about half of the cases. (1) Owing to the limited number of studies, the absence of a uniform definition, the high risk of bias, and the mixed results of studies, no firm conclusion about the sustainability of professionals’ adherence to guidelines in medical practice can be drawn. Results Systematic review sustainabilityFor this review, 4219 items were retrieved and screened based on title and abstract, 185 studies were assessed based on full text reading and 14 studies were selected for analyses. This data file contains the endnote file with all items and the classification.