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description Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2021 United KingdomPublisher:MDPI AG Authors: Samuel Kwasi Opoku; Walter Leal Filho; Fudjumdjum Hubert; Oluwabunmi Adejumo;Climate change is a global problem, which affects the various geographical regions at different levels. It is also associated with a wide range of human health problems, which pose a burden to health systems, especially in regions such as Africa. Indeed, across the African continent public health systems are under severe pressure, partly due to their fragile socioeconomic conditions. This paper reports on a cross-sectional study in six African countries (Ghana, Nigeria, South Africa, Namibia, Ethiopia, and Kenya) aimed at assessing their vulnerabilities to climate change, focusing on its impacts on human health. The study evaluated the levels of information, knowledge, and perceptions of public health professionals. It also examined the health systems’ preparedness to cope with these health hazards, the available resources, and those needed to build resilience to the country’s vulnerable population, as perceived by health professionals. The results revealed that 63.1% of the total respondents reported that climate change had been extensively experienced in the past years, while 32% claimed that the sampled countries had experienced them to some extent. Nigerian respondents recorded the highest levels (67.7%), followed by Kenya with 66.6%. South Africa had the lowest level of impact as perceived by the respondents (50.0%) when compared with the other sampled countries. All respondents from Ghana and Namibia reported that health problems caused by climate change are common in the two countries. As perceived by the health professionals, the inadequate resources reiterate the need for infrastructural resources, medical equipment, emergency response resources, and technical support. The study’s recommendations include the need to improve current policies at all levels (i.e., national, regional, and local) on climate change and public health and to strengthen health professionals’ skills. Improving the basic knowledge of health institutions to better respond to a changing climate is also recommended. The study provides valuable insights which may be helpful to other nations in Sub-Saharan Africa.
International Journa... arrow_drop_down International Journal of Environmental Research and Public HealthOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/1660-4601/18/9/4672/pdfData sources: Multidisciplinary Digital Publishing InstituteInternational Journal of Environmental Research and Public HealthArticle . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefInternational Journal of Environmental Research and Public HealthArticleLicense: CC BYData sources: UnpayWallInternational Journal of Environmental Research and Public HealthArticle . 2021Data sources: Europe PubMed Centrale-space at Manchester Metropolitan UniversityArticle . 2021Data sources: e-space at Manchester Metropolitan Universityadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/ijerph18094672&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert International Journa... arrow_drop_down International Journal of Environmental Research and Public HealthOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/1660-4601/18/9/4672/pdfData sources: Multidisciplinary Digital Publishing InstituteInternational Journal of Environmental Research and Public HealthArticle . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefInternational Journal of Environmental Research and Public HealthArticleLicense: CC BYData sources: UnpayWallInternational Journal of Environmental Research and Public HealthArticle . 2021Data sources: Europe PubMed Centrale-space at Manchester Metropolitan UniversityArticle . 2021Data sources: e-space at Manchester Metropolitan Universityadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/ijerph18094672&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2004Publisher:Elsevier BV Authors: Patricia Metcalf; Robert Scragg;pmid: 15533582
The association between alcohol and blood glucose levels, and whether it is modified by other variables, was examined in a cross-sectional survey of 5518 staff aged 40-65 years at worksites in Auckland and Tokoroa, New Zealand. Diabetes was determined by oral glucose-tolerance tests using 1999 WHO criteria. Usual alcohol intake in the previous 3 months, measured by food frequency questionnaire, was related positively with fasting triglycerides and high-density-lipoprotein (HDL)-cholesterol, and unrelated with fasting glucose, but had an approximate U-shaped relationship with 2-h glucose, which varied from an adjusted mean (S.E.) of 5.62 (0.08) mmol/l in non-drinkers, down to 5.34 (0.08) mmol/l in light alcohol drinkers (alcohol or =20 g per day). Adjusting further for triglycerides increased the mean difference in 2-h glucose for all drinking categories compared with non-drinkers, particularly for heavy drinkers (> or =20 g per day), from -0.22 (S.E. = 0.10) to -0.37 (0.10) mmol/l. The confounding effect of triglycerides suggests alcohol may affect the diabetes risk by a mechanism related to the triglyceride metabolism, which in heavy drinkers may counteract the protective effect of improved insulin sensitivity, resulting in the U-shaped relationship between alcohol and diabetes described in previous studies.
Diabetes Research an... arrow_drop_down Diabetes Research and Clinical PracticeArticle . 2004 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.diabres.2004.02.022&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert Diabetes Research an... arrow_drop_down Diabetes Research and Clinical PracticeArticle . 2004 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.diabres.2004.02.022&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2002 FrancePublisher:Copernicus GmbH Ch. George; L. Gutzwiller; Markus Ammann; N. Lahoutifard; N. Lahoutifard; Barbara Ervens; Barbara Ervens;Abstract. The impact of multiphase reactions involving nitrogen dioxide (NO2) and aromatic compounds was simulated in this study. A mechanism (CAPRAM 2.4, MODAC Mechanism) was applied for the aqueous phase reactions, whereas RACM was applied for the gas phase chemistry. Liquid droplets were considered as monodispersed with a mean radius of 0.1 µm and a liquid content (LC) of 50 µg m-3. The multiphase mechanism has been further extended to the chemistry of aromatics, i.e. reactions involving benzene, toluene, xylene, phenol and cresol have been added. In addition, reaction of NO2 with dissociated hydroxyl substituted aromatic compounds has also been implemented. These reactions proceed through charge exchange leading to nitrite ions and therefore to nitrous acid formation. The strength of this source was explored under urban polluted conditions. It was shown that it may increase gas phase HONO levels under some conditions and that the extent of this effect is strongly pH dependent. Especially under moderate acidic conditions (i.e. pH above 4) this source may represent more than 75% of the total HONO/NO2 - production rate, but this contribution drops down close to zero in acidic droplets (as those often encountered in urban environments).
INRIA a CCSD electro... arrow_drop_down INRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverAtmospheric Chemistry and Physics (ACP)Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: Crossrefhttps://doi.org/10.5194/acpd-2...Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: CrossrefINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serveradd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/acp-2-215-2002&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert INRIA a CCSD electro... arrow_drop_down INRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverAtmospheric Chemistry and Physics (ACP)Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: Crossrefhttps://doi.org/10.5194/acpd-2...Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: CrossrefINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serveradd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/acp-2-215-2002&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2016Publisher:Springer Science and Business Media LLC Authors: Liu, Na; Jørgensen, Uffe; Lærke, Poul Erik;Eight willow (Salix) clones (Inger, Klara, Linnea, Resolution, Stina, Terra Nova, Tora, Tordis) were planted on two soil types in Denmark. The biomass quality was evaluated after 3 years of growth by measuring differences in concentrations of 14 elements associated with ash behavior during combustion, and total ash content. Three-year-old shoots of Tordis and Tora performed in general the best with relatively lower mean concentrations of K, Ca, Na, S, and total ash content than other clones across the two experimental sites. Terra Nova was the least suited for combustion as it contained up to 22, 27, 35, and 23 % higher concentrations of K, S, Ca, and total ash than the other clones. In addition to clone and site, appropriate management could further improve the fuel quality of willow biomass. When shoots of Inger were harvested annually (1-year shoots) high concentrations of K and Cl were found in all three consecutive harvests, but concentrations decreased significantly when rotation length was extended beyond 1 year of growth. Significant decreases of Mg, Na, P, S, and Zn were also registered from 2- to 3-year-old shoots. No difference in quality of biomass was found between two plant densities (8000 and 12,000 trees ha−1) of the clones Inger and Tora after the first 3-year rotation when grown at the site with a coarse sandy soil. The study indicates considerable diversity in concentration of elements within commercially available willow cultivars and suggests breeders and growers to select clones not only according to biomass yield potential but also according to biomass quality.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s12155-016-9762-y&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s12155-016-9762-y&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2021 SpainPublisher:MDPI AG Authors: Isabel del Arco; Patricia Silva; Oscar Flores;doi: 10.3390/su13010375
A quantitative study was carried out with the aim of analyzing the perspective of the students in relation to the factors that have influenced quality teaching during the confinement period resulting from the SARS-CoV-2 pandemic. To do this, an ad hoc questionnaire was designed and conducted in the months of June–July 2020. The sample consisted of 893 people who were studying at various Spanish universities. The results show little diversity in teaching methodologies; virtual teaching was carried out with the same parameters as face-to-face teaching. The role of the student body was one of passivity, consisting of little interaction with the teachers. Although it is true that there were no difficulties in following the course, there was limited attention paid to the emotional well-being of the students. Amongst the conclusions garnered significant, we point out the need to develop the adaptability of university teaching staff to unforeseen situations, as well as a continuing reflection on the model used in the teaching process mediated by digital technologies and the importance of promoting greater autonomy and self-regulation during learning.
Sustainability arrow_drop_down SustainabilityOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/2071-1050/13/1/375/pdfData sources: Multidisciplinary Digital Publishing InstituteRecolector de Ciencia Abierta, RECOLECTAArticleLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2021License: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTAResearch Repository of CataloniaArticleLicense: CC BYData sources: Research Repository of CataloniaDiposit Digital de la Universitat de BarcelonaArticle . 2021License: CC BYData sources: Diposit Digital de la Universitat de BarcelonaRecolector de Ciencia Abierta, RECOLECTAArticle . 2021Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/su13010375&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert Sustainability arrow_drop_down SustainabilityOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/2071-1050/13/1/375/pdfData sources: Multidisciplinary Digital Publishing InstituteRecolector de Ciencia Abierta, RECOLECTAArticleLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2021License: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTAResearch Repository of CataloniaArticleLicense: CC BYData sources: Research Repository of CataloniaDiposit Digital de la Universitat de BarcelonaArticle . 2021License: CC BYData sources: Diposit Digital de la Universitat de BarcelonaRecolector de Ciencia Abierta, RECOLECTAArticle . 2021Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/su13010375&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Conference object , Article 2015Publisher:IEEE Authors: Przemyslaw Komarnicki; Pio Lombardi; Christian Klabunde; Zbigniew A. Styczynski; +1 AuthorsPrzemyslaw Komarnicki; Pio Lombardi; Christian Klabunde; Zbigniew A. Styczynski; Natalia Moskalenko;The variability of large scale wind power generation at high penetration levels has a significant impact on the secure and economic operation of onshore power systems. Grid bottlenecks, high gradients and wasting of wind energy can be avoided using local Energy Storage Systems (ESS) with dedicated power and capacity. The storage type considered in this study is an adiabatic compressed air energy storage (ACAES). This paper presents a comparison of different ESS applications aiming both to increase the profit of the power plant operator in selling the electricity into the electricity market and to support the intermittent electricity production of the wind park. This contribution presents the investigation methodology and discusses computation results for a region in Germany.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/pesgm.2015.7286082&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/pesgm.2015.7286082&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2012 ItalyPublisher:Elsevier BV Ceccanti Mauro; Mancinelli Rosanna; Tirassa Paola; Laviola Giovanni; Rossi Simona W; Romeo Marina M; Fiore Marco;Prenatal ethanol exposure produces severe changes in brain, liver, and kidney through mechanisms involving growth factors. These molecules regulate survival, differentiation, maintenance, and connectivity of brain, liver, and kidney cells. Despite the abundant available data on the short and mid-lasting effects of ethanol intoxication, only few data show the long-lasting damage induced by early ethanol administration. The aim of this study was to investigate changes in nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), hepatocyte growth factor (HGF), and vascular endothelial growth factor (VEGF) in brain areas, liver, and kidney of 18-mo-old male mice exposed perinatally to ethanol at 11% vol or to red wine at the same ethanol concentration. The authors found that ethanol per se elevated NGF, BDNF, HGF, and VEGF measured by ELISA in brain limbic system areas. In the liver, early exposure to ethanol solution and red wine depleted BDNF and VEGF concentrations. In the kidney, red wine exposure only decreased VEGF. In conclusion, the present study shows that, in aged mice, early administration of ethanol solution induced long-lasting damage at growth factor levels in frontal cortex, hippocampus, and liver but not in kidney. Otherwise, in mice exposed to red wine, significant changes were observed in the liver and kidney but not in the hippocampus and frontal cortex. The brain differences in ethanol-induced toxicity when ethanol is administered alone or in red wine may be related to compounds with antioxidant properties present in the red wine.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.neurobiolaging.2010.03.005&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.neurobiolaging.2010.03.005&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2016Publisher:Ivyspring International Publisher Funded by:NIH | DISEASE MODELING OF ALCOH...NIH| DISEASE MODELING OF ALCOHOL RELATED HEPATOCELLULAR CARCINOMA USING PATIENT IPSCSAuthors: Yoon Young Jang; Abhijeet Deshmukh; Lipeng Tian; Neha Prasad;Alcohol consumption has long been a global problem affecting human health, and has been found to influence both fetal and adult liver functions. However, how alcohol affects human liver development and liver progenitor cells remains largely unknown. Here, we used human induced pluripotent stem cells (iPSCs) as a model to examine the effects of alcohol, on multi-stage hepatic cells including hepatic progenitors, early and mature hepatocyte-like cells derived from human iPSCs. While alcohol has little effect on endoderm development from iPSCs, it reduces formation of hepatic progenitor cells during early hepatic specification. The proliferative activities of early and mature hepatocyte-like cells are significantly decreased after alcohol exposure. Importantly, at a mature stage of hepatocyte-like cells, alcohol treatment increases two liver progenitor subsets, causes oxidative mitochondrial injury and results in liver disease phenotypes (i.e., steatosis and hepatocellular carcinoma associated markers) in a dose dependent manner. Some of the phenotypes were significantly improved by antioxidant treatment. This report suggests that fetal alcohol exposure may impair generation of hepatic progenitors at early stage of hepatic specification and decrease proliferation of fetal hepatocytes; meanwhile alcohol injury in post-natal or mature stage human liver may contribute to disease phenotypes. This human iPSC model of alcohol-induced liver injury can be highly valuable for investigating alcoholic injury in the fetus as well as understanding the pathogenesis and ultimately developing effective treatment for alcoholic liver disease in adults.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7150/ijbs.15811&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7150/ijbs.15811&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2017 SpainPublisher:Wiley Fernando Simón; Javier González-Miguel; Alicia Diosdado; Paula Josefina Gómez; Rodrigo Morchón; Vladimir Kartashev;Vector-borne transmitted helminthic zoonosis affects the health and economy of both developing and developed countries. The concept of episystem includes the set of biological, environmental, and epidemiological elements of these diseases in defined geographic and temporal scales. Dirofilariasis caused by different species of the genusDirofilariais a disease affecting domestic and wild canines and felines and man, transmitted by different species of culicid mosquitoes. This complexity is increased becauseDirofilariaspecies harbor intracellular symbiontWolbachiabacteriae, which play a key role in the embryogenesis and development of dirofilariae and in the inflammatory pathology of the disease. In addition, the vector transmission makes the dirofilariasis susceptible to the influence of the climate and its variations. The present review addresses the analysis of dirofilariasis from the point of view of the episystem, analyzing the complex network of interactions established between biological components, climate, and factors related to human activity, as well as the different problems they pose. The progress of knowledge on human and animal dirofilariasis is largely due to the multidisciplinary approach. Nevertheless, different aspects of the disease need to continue being investigated and cooperation between countries and specialists involved should be intensified.
BioMed Research Inte... arrow_drop_down Recolector de Ciencia Abierta, RECOLECTAArticle . 2017Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2017 . Peer-reviewedData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1155/2017/6436130&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert BioMed Research Inte... arrow_drop_down Recolector de Ciencia Abierta, RECOLECTAArticle . 2017Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2017 . Peer-reviewedData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1155/2017/6436130&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2016Publisher:Springer Science and Business Media LLC Ajit Varma; Monika Arora; Devendra Kumar Choudhary; Malik Zainul Abdin; Parul Saxena;pmid: 26745979
At present, Artemisia annua L. is the major source of artemisinin production. To control the outbreaks of malaria, artemisinin combination therapies (ACTs) are recommended, and hence an ample amount of artemisinin is required for ACTs manufacture to save millions of lives. The low yield of this antimalarial drug in A. annua L. plants (0.01-1.1%) ensues its short supply and high cost, thus making it a topic of scrutiny worldwide. In this study, the effects of root endophyte, Piriformospora indica strain DSM 11827 and nitrogen fixing bacterium, Azotobacter chroococcum strain W-5, either singly and/or in combination for artemisinin production in A. annua L. plants have been studied under poly house conditions. The plant growth was monitored by measuring parameters like height of plant, total dry weight and leaf yield with an increase of 63.51, 52.61 and 79.70% respectively, for treatment with dual biological consortium, as compared to that of control plants. This significant improvement in biomass was associated with higher total chlorophyll content (59.29%) and enhanced nutrition (especially nitrogen and phosphorus, 55.75 and 86.21% respectively). The concentration of artemisinin along with expression patterns of artemisinin biosynthesis genes were appreciably higher in dual treatment, which showed positive correlation. The study suggested the potential use of the consortium P. indica strain DSM 11827 and A. chroococcum strain W-5 in A. annua L. plants for increased overall productivity and sustainable agriculture.
World Journal of Mic... arrow_drop_down World Journal of Microbiology and BiotechnologyArticle . 2016 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11274-015-1972-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert World Journal of Mic... arrow_drop_down World Journal of Microbiology and BiotechnologyArticle . 2016 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11274-015-1972-5&type=result"></script>'); --> </script>
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description Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2021 United KingdomPublisher:MDPI AG Authors: Samuel Kwasi Opoku; Walter Leal Filho; Fudjumdjum Hubert; Oluwabunmi Adejumo;Climate change is a global problem, which affects the various geographical regions at different levels. It is also associated with a wide range of human health problems, which pose a burden to health systems, especially in regions such as Africa. Indeed, across the African continent public health systems are under severe pressure, partly due to their fragile socioeconomic conditions. This paper reports on a cross-sectional study in six African countries (Ghana, Nigeria, South Africa, Namibia, Ethiopia, and Kenya) aimed at assessing their vulnerabilities to climate change, focusing on its impacts on human health. The study evaluated the levels of information, knowledge, and perceptions of public health professionals. It also examined the health systems’ preparedness to cope with these health hazards, the available resources, and those needed to build resilience to the country’s vulnerable population, as perceived by health professionals. The results revealed that 63.1% of the total respondents reported that climate change had been extensively experienced in the past years, while 32% claimed that the sampled countries had experienced them to some extent. Nigerian respondents recorded the highest levels (67.7%), followed by Kenya with 66.6%. South Africa had the lowest level of impact as perceived by the respondents (50.0%) when compared with the other sampled countries. All respondents from Ghana and Namibia reported that health problems caused by climate change are common in the two countries. As perceived by the health professionals, the inadequate resources reiterate the need for infrastructural resources, medical equipment, emergency response resources, and technical support. The study’s recommendations include the need to improve current policies at all levels (i.e., national, regional, and local) on climate change and public health and to strengthen health professionals’ skills. Improving the basic knowledge of health institutions to better respond to a changing climate is also recommended. The study provides valuable insights which may be helpful to other nations in Sub-Saharan Africa.
International Journa... arrow_drop_down International Journal of Environmental Research and Public HealthOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/1660-4601/18/9/4672/pdfData sources: Multidisciplinary Digital Publishing InstituteInternational Journal of Environmental Research and Public HealthArticle . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefInternational Journal of Environmental Research and Public HealthArticleLicense: CC BYData sources: UnpayWallInternational Journal of Environmental Research and Public HealthArticle . 2021Data sources: Europe PubMed Centrale-space at Manchester Metropolitan UniversityArticle . 2021Data sources: e-space at Manchester Metropolitan Universityadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/ijerph18094672&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert International Journa... arrow_drop_down International Journal of Environmental Research and Public HealthOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/1660-4601/18/9/4672/pdfData sources: Multidisciplinary Digital Publishing InstituteInternational Journal of Environmental Research and Public HealthArticle . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefInternational Journal of Environmental Research and Public HealthArticleLicense: CC BYData sources: UnpayWallInternational Journal of Environmental Research and Public HealthArticle . 2021Data sources: Europe PubMed Centrale-space at Manchester Metropolitan UniversityArticle . 2021Data sources: e-space at Manchester Metropolitan Universityadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/ijerph18094672&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2004Publisher:Elsevier BV Authors: Patricia Metcalf; Robert Scragg;pmid: 15533582
The association between alcohol and blood glucose levels, and whether it is modified by other variables, was examined in a cross-sectional survey of 5518 staff aged 40-65 years at worksites in Auckland and Tokoroa, New Zealand. Diabetes was determined by oral glucose-tolerance tests using 1999 WHO criteria. Usual alcohol intake in the previous 3 months, measured by food frequency questionnaire, was related positively with fasting triglycerides and high-density-lipoprotein (HDL)-cholesterol, and unrelated with fasting glucose, but had an approximate U-shaped relationship with 2-h glucose, which varied from an adjusted mean (S.E.) of 5.62 (0.08) mmol/l in non-drinkers, down to 5.34 (0.08) mmol/l in light alcohol drinkers (alcohol or =20 g per day). Adjusting further for triglycerides increased the mean difference in 2-h glucose for all drinking categories compared with non-drinkers, particularly for heavy drinkers (> or =20 g per day), from -0.22 (S.E. = 0.10) to -0.37 (0.10) mmol/l. The confounding effect of triglycerides suggests alcohol may affect the diabetes risk by a mechanism related to the triglyceride metabolism, which in heavy drinkers may counteract the protective effect of improved insulin sensitivity, resulting in the U-shaped relationship between alcohol and diabetes described in previous studies.
Diabetes Research an... arrow_drop_down Diabetes Research and Clinical PracticeArticle . 2004 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.diabres.2004.02.022&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert Diabetes Research an... arrow_drop_down Diabetes Research and Clinical PracticeArticle . 2004 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.diabres.2004.02.022&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2002 FrancePublisher:Copernicus GmbH Ch. George; L. Gutzwiller; Markus Ammann; N. Lahoutifard; N. Lahoutifard; Barbara Ervens; Barbara Ervens;Abstract. The impact of multiphase reactions involving nitrogen dioxide (NO2) and aromatic compounds was simulated in this study. A mechanism (CAPRAM 2.4, MODAC Mechanism) was applied for the aqueous phase reactions, whereas RACM was applied for the gas phase chemistry. Liquid droplets were considered as monodispersed with a mean radius of 0.1 µm and a liquid content (LC) of 50 µg m-3. The multiphase mechanism has been further extended to the chemistry of aromatics, i.e. reactions involving benzene, toluene, xylene, phenol and cresol have been added. In addition, reaction of NO2 with dissociated hydroxyl substituted aromatic compounds has also been implemented. These reactions proceed through charge exchange leading to nitrite ions and therefore to nitrous acid formation. The strength of this source was explored under urban polluted conditions. It was shown that it may increase gas phase HONO levels under some conditions and that the extent of this effect is strongly pH dependent. Especially under moderate acidic conditions (i.e. pH above 4) this source may represent more than 75% of the total HONO/NO2 - production rate, but this contribution drops down close to zero in acidic droplets (as those often encountered in urban environments).
INRIA a CCSD electro... arrow_drop_down INRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverAtmospheric Chemistry and Physics (ACP)Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: Crossrefhttps://doi.org/10.5194/acpd-2...Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: CrossrefINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serveradd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/acp-2-215-2002&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert INRIA a CCSD electro... arrow_drop_down INRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverAtmospheric Chemistry and Physics (ACP)Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: Crossrefhttps://doi.org/10.5194/acpd-2...Article . 2002 . Peer-reviewedLicense: CC BY NC SAData sources: CrossrefINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serverINRIA a CCSD electronic archive serverArticle . 2002Data sources: INRIA a CCSD electronic archive serveradd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/acp-2-215-2002&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2016Publisher:Springer Science and Business Media LLC Authors: Liu, Na; Jørgensen, Uffe; Lærke, Poul Erik;Eight willow (Salix) clones (Inger, Klara, Linnea, Resolution, Stina, Terra Nova, Tora, Tordis) were planted on two soil types in Denmark. The biomass quality was evaluated after 3 years of growth by measuring differences in concentrations of 14 elements associated with ash behavior during combustion, and total ash content. Three-year-old shoots of Tordis and Tora performed in general the best with relatively lower mean concentrations of K, Ca, Na, S, and total ash content than other clones across the two experimental sites. Terra Nova was the least suited for combustion as it contained up to 22, 27, 35, and 23 % higher concentrations of K, S, Ca, and total ash than the other clones. In addition to clone and site, appropriate management could further improve the fuel quality of willow biomass. When shoots of Inger were harvested annually (1-year shoots) high concentrations of K and Cl were found in all three consecutive harvests, but concentrations decreased significantly when rotation length was extended beyond 1 year of growth. Significant decreases of Mg, Na, P, S, and Zn were also registered from 2- to 3-year-old shoots. No difference in quality of biomass was found between two plant densities (8000 and 12,000 trees ha−1) of the clones Inger and Tora after the first 3-year rotation when grown at the site with a coarse sandy soil. The study indicates considerable diversity in concentration of elements within commercially available willow cultivars and suggests breeders and growers to select clones not only according to biomass yield potential but also according to biomass quality.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s12155-016-9762-y&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s12155-016-9762-y&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal , Other literature type 2021 SpainPublisher:MDPI AG Authors: Isabel del Arco; Patricia Silva; Oscar Flores;doi: 10.3390/su13010375
A quantitative study was carried out with the aim of analyzing the perspective of the students in relation to the factors that have influenced quality teaching during the confinement period resulting from the SARS-CoV-2 pandemic. To do this, an ad hoc questionnaire was designed and conducted in the months of June–July 2020. The sample consisted of 893 people who were studying at various Spanish universities. The results show little diversity in teaching methodologies; virtual teaching was carried out with the same parameters as face-to-face teaching. The role of the student body was one of passivity, consisting of little interaction with the teachers. Although it is true that there were no difficulties in following the course, there was limited attention paid to the emotional well-being of the students. Amongst the conclusions garnered significant, we point out the need to develop the adaptability of university teaching staff to unforeseen situations, as well as a continuing reflection on the model used in the teaching process mediated by digital technologies and the importance of promoting greater autonomy and self-regulation during learning.
Sustainability arrow_drop_down SustainabilityOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/2071-1050/13/1/375/pdfData sources: Multidisciplinary Digital Publishing InstituteRecolector de Ciencia Abierta, RECOLECTAArticleLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2021License: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTAResearch Repository of CataloniaArticleLicense: CC BYData sources: Research Repository of CataloniaDiposit Digital de la Universitat de BarcelonaArticle . 2021License: CC BYData sources: Diposit Digital de la Universitat de BarcelonaRecolector de Ciencia Abierta, RECOLECTAArticle . 2021Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/su13010375&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert Sustainability arrow_drop_down SustainabilityOther literature type . 2021License: CC BYFull-Text: http://www.mdpi.com/2071-1050/13/1/375/pdfData sources: Multidisciplinary Digital Publishing InstituteRecolector de Ciencia Abierta, RECOLECTAArticleLicense: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2021License: CC BYData sources: Recolector de Ciencia Abierta, RECOLECTAResearch Repository of CataloniaArticleLicense: CC BYData sources: Research Repository of CataloniaDiposit Digital de la Universitat de BarcelonaArticle . 2021License: CC BYData sources: Diposit Digital de la Universitat de BarcelonaRecolector de Ciencia Abierta, RECOLECTAArticle . 2021Data sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/su13010375&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Conference object , Article 2015Publisher:IEEE Authors: Przemyslaw Komarnicki; Pio Lombardi; Christian Klabunde; Zbigniew A. Styczynski; +1 AuthorsPrzemyslaw Komarnicki; Pio Lombardi; Christian Klabunde; Zbigniew A. Styczynski; Natalia Moskalenko;The variability of large scale wind power generation at high penetration levels has a significant impact on the secure and economic operation of onshore power systems. Grid bottlenecks, high gradients and wasting of wind energy can be avoided using local Energy Storage Systems (ESS) with dedicated power and capacity. The storage type considered in this study is an adiabatic compressed air energy storage (ACAES). This paper presents a comparison of different ESS applications aiming both to increase the profit of the power plant operator in selling the electricity into the electricity market and to support the intermittent electricity production of the wind park. This contribution presents the investigation methodology and discusses computation results for a region in Germany.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/pesgm.2015.7286082&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/pesgm.2015.7286082&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2012 ItalyPublisher:Elsevier BV Ceccanti Mauro; Mancinelli Rosanna; Tirassa Paola; Laviola Giovanni; Rossi Simona W; Romeo Marina M; Fiore Marco;Prenatal ethanol exposure produces severe changes in brain, liver, and kidney through mechanisms involving growth factors. These molecules regulate survival, differentiation, maintenance, and connectivity of brain, liver, and kidney cells. Despite the abundant available data on the short and mid-lasting effects of ethanol intoxication, only few data show the long-lasting damage induced by early ethanol administration. The aim of this study was to investigate changes in nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), hepatocyte growth factor (HGF), and vascular endothelial growth factor (VEGF) in brain areas, liver, and kidney of 18-mo-old male mice exposed perinatally to ethanol at 11% vol or to red wine at the same ethanol concentration. The authors found that ethanol per se elevated NGF, BDNF, HGF, and VEGF measured by ELISA in brain limbic system areas. In the liver, early exposure to ethanol solution and red wine depleted BDNF and VEGF concentrations. In the kidney, red wine exposure only decreased VEGF. In conclusion, the present study shows that, in aged mice, early administration of ethanol solution induced long-lasting damage at growth factor levels in frontal cortex, hippocampus, and liver but not in kidney. Otherwise, in mice exposed to red wine, significant changes were observed in the liver and kidney but not in the hippocampus and frontal cortex. The brain differences in ethanol-induced toxicity when ethanol is administered alone or in red wine may be related to compounds with antioxidant properties present in the red wine.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.neurobiolaging.2010.03.005&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.neurobiolaging.2010.03.005&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2016Publisher:Ivyspring International Publisher Funded by:NIH | DISEASE MODELING OF ALCOH...NIH| DISEASE MODELING OF ALCOHOL RELATED HEPATOCELLULAR CARCINOMA USING PATIENT IPSCSAuthors: Yoon Young Jang; Abhijeet Deshmukh; Lipeng Tian; Neha Prasad;Alcohol consumption has long been a global problem affecting human health, and has been found to influence both fetal and adult liver functions. However, how alcohol affects human liver development and liver progenitor cells remains largely unknown. Here, we used human induced pluripotent stem cells (iPSCs) as a model to examine the effects of alcohol, on multi-stage hepatic cells including hepatic progenitors, early and mature hepatocyte-like cells derived from human iPSCs. While alcohol has little effect on endoderm development from iPSCs, it reduces formation of hepatic progenitor cells during early hepatic specification. The proliferative activities of early and mature hepatocyte-like cells are significantly decreased after alcohol exposure. Importantly, at a mature stage of hepatocyte-like cells, alcohol treatment increases two liver progenitor subsets, causes oxidative mitochondrial injury and results in liver disease phenotypes (i.e., steatosis and hepatocellular carcinoma associated markers) in a dose dependent manner. Some of the phenotypes were significantly improved by antioxidant treatment. This report suggests that fetal alcohol exposure may impair generation of hepatic progenitors at early stage of hepatic specification and decrease proliferation of fetal hepatocytes; meanwhile alcohol injury in post-natal or mature stage human liver may contribute to disease phenotypes. This human iPSC model of alcohol-induced liver injury can be highly valuable for investigating alcoholic injury in the fetus as well as understanding the pathogenesis and ultimately developing effective treatment for alcoholic liver disease in adults.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7150/ijbs.15811&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.7150/ijbs.15811&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type , Journal 2017 SpainPublisher:Wiley Fernando Simón; Javier González-Miguel; Alicia Diosdado; Paula Josefina Gómez; Rodrigo Morchón; Vladimir Kartashev;Vector-borne transmitted helminthic zoonosis affects the health and economy of both developing and developed countries. The concept of episystem includes the set of biological, environmental, and epidemiological elements of these diseases in defined geographic and temporal scales. Dirofilariasis caused by different species of the genusDirofilariais a disease affecting domestic and wild canines and felines and man, transmitted by different species of culicid mosquitoes. This complexity is increased becauseDirofilariaspecies harbor intracellular symbiontWolbachiabacteriae, which play a key role in the embryogenesis and development of dirofilariae and in the inflammatory pathology of the disease. In addition, the vector transmission makes the dirofilariasis susceptible to the influence of the climate and its variations. The present review addresses the analysis of dirofilariasis from the point of view of the episystem, analyzing the complex network of interactions established between biological components, climate, and factors related to human activity, as well as the different problems they pose. The progress of knowledge on human and animal dirofilariasis is largely due to the multidisciplinary approach. Nevertheless, different aspects of the disease need to continue being investigated and cooperation between countries and specialists involved should be intensified.
BioMed Research Inte... arrow_drop_down Recolector de Ciencia Abierta, RECOLECTAArticle . 2017Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2017 . Peer-reviewedData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1155/2017/6436130&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert BioMed Research Inte... arrow_drop_down Recolector de Ciencia Abierta, RECOLECTAArticle . 2017Data sources: Recolector de Ciencia Abierta, RECOLECTARecolector de Ciencia Abierta, RECOLECTAArticle . 2017 . Peer-reviewedData sources: Recolector de Ciencia Abierta, RECOLECTAadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1155/2017/6436130&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2016Publisher:Springer Science and Business Media LLC Ajit Varma; Monika Arora; Devendra Kumar Choudhary; Malik Zainul Abdin; Parul Saxena;pmid: 26745979
At present, Artemisia annua L. is the major source of artemisinin production. To control the outbreaks of malaria, artemisinin combination therapies (ACTs) are recommended, and hence an ample amount of artemisinin is required for ACTs manufacture to save millions of lives. The low yield of this antimalarial drug in A. annua L. plants (0.01-1.1%) ensues its short supply and high cost, thus making it a topic of scrutiny worldwide. In this study, the effects of root endophyte, Piriformospora indica strain DSM 11827 and nitrogen fixing bacterium, Azotobacter chroococcum strain W-5, either singly and/or in combination for artemisinin production in A. annua L. plants have been studied under poly house conditions. The plant growth was monitored by measuring parameters like height of plant, total dry weight and leaf yield with an increase of 63.51, 52.61 and 79.70% respectively, for treatment with dual biological consortium, as compared to that of control plants. This significant improvement in biomass was associated with higher total chlorophyll content (59.29%) and enhanced nutrition (especially nitrogen and phosphorus, 55.75 and 86.21% respectively). The concentration of artemisinin along with expression patterns of artemisinin biosynthesis genes were appreciably higher in dual treatment, which showed positive correlation. The study suggested the potential use of the consortium P. indica strain DSM 11827 and A. chroococcum strain W-5 in A. annua L. plants for increased overall productivity and sustainable agriculture.
World Journal of Mic... arrow_drop_down World Journal of Microbiology and BiotechnologyArticle . 2016 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11274-015-1972-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eumore_vert World Journal of Mic... arrow_drop_down World Journal of Microbiology and BiotechnologyArticle . 2016 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s11274-015-1972-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu