EU-TRAINS aims to reinforce the supply chain on sensors for biomechanics and cardiovascular system real-time monitoring targeting applications in the fields of fitness and healthcare. It leverages from the strength of EU digital microsystem and design to support a 100% made-in-Europe supply chain of solutions which encompass smart-textile integration as well as advanced AI-based edge-cloud data processing. In details the following outcomes are foreseen: - Textile integrated electronic systems for real-time monitoring of hearth, respiratory and movement parameters on-the-air and in-water through an interdisciplinary approach; - Semiconductor technologies which allow the re-use of micro-nano systems both in the sports and in the healthcare sectors; - Miniaturized devices allowing the capturing of bio-chemical parameters able to withstand harsh ambient conditions such as salt fogs, chlorine, detergents, high and low temperatures, etc. The following key activities are targeted: - Development, prototyping and demonstration of versatile sensors with edge AI features for improved precision and reliability, that can also be integrated in textiles as well as in smart wearable wrist-watches and in sport equipment and gears targeting also underwater applications; - Cloud-edge Artificial Intelligence combined approaches for reliable diagnosis of body parameters. This will comprise sensor’s self-learning, remote update, multi-sensing approaches based on sensor arrays; - Novel materials that support electronics printing in textiles with stretchability and self-healing capabilities. Societal benefits are foreseen in the transition to a healthier lifestyle by promoting regular physical activity through affordable tools and services for a large audience, including people with disabilities. Moreover, this will impact the smart/remote-healthcare sector which will benefit of the availability of low-cost microfabricated solutions for intelligent, versatile, connected body sensors.

H2TRAIN proposal is funded on the sixth edition of the Electronic Components and Systems (ECS) Strategic Research and Innovation Agenda (ECS-SRIA) topics and major challenges for enabling digital technologies in holistic health-lifestyle supported by artificial intelligence (AI) networks. Biosensors for e-health and smart tracking of sport and fitness are a class of devices that is dominating the consumer and professional market with an unprecedented growth. Despite the impressive capabilities of recent approaches, several prospective revolutionary improvements are still open points, mainly in relationship with four factors: sensing new biosignals and tracking new activity patterns; improving battery lifetime and energy management for continuous use; and secure, reliable and efficient data analysis with AI algorithms and connectivity with the IoT. H2TRAIN aims at advancing the state of the art in this respect, taking profit from the remarkable properties and synergistic potential of one-dimensional (1D) and two-dimensional (2D) materials (1DM and 2DM), enabling more sensitive, efficient, and miniaturized biosensing capabilities within the established CMOS technology framework. This will contribute to the growth of e-health services assisted by AI and will fortify the development of Internet of Things (IoT) applications in health & wellbeing and digital society. H2TRAIN not only facilitates digital technology but also involves the development of new 1DM and 2DM-based devices for sensing, energy harvesting and supercapacitor storage. These innovations serve to integrate sport and health activities into IoT applications, making them accessible as wearable technology. H2TRAIN combines mature CMOS technology products for health and sport sensing with embedded intelligence as a cross-sectional technology. This combination offers a broad spectrum of technology demonstrators (TD) based on advanced sensors, such as tattoo sweat, C-reactive protein, cortisol and lactate.

Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the shortage of scientists with interdisciplinary training that can navigate with ease between the academic, industrial and clinical sectors, and that have the scientific and complementary skills, together with an innovative outlook, to convert research findings into commercial and clinical applications. This proposal will bring young researchers together with world-leading academics, clinicians and industry personnel, who are united in (1) their goal of forming a network of excellence aimed at understanding the ER stress response mechanistically and quantitatively and (2) applying this understanding to identify and validate the most suitable intervention points in order to provide innovative knowledge-driven strategies for the treatment of ER stress-associated diseases. The TRAIN-ERS network will provide early stage researchers (ESRs) with high quality scientific and complementary skills training combined with international, intersectoral work experience. This will produce highly trained, innovative, creative and entrepreneurial ESRs with greatly enhanced career prospects, who will continue to advance the state of the art in the Biomedical field in their further careers, and will confidently navigate at the interface of academic, clinical and private sector research. The TRAIN-ERS research programme will provide the ESR’s with the knowledge and the cutting edge scientific and technical skills that will drive our understanding and exploitation of the ER stress response for therapeutic and diagnostic purposes.

I-Media-Cities is the initiative of 9 European Film Libraries, 5 research institutions, 2 technological providers and a specialist of digital business models to share access to and valorise audiovisual (AV) content from their collections for research purposes in a wide range of social sciences (sociology, anthropology, urban planning, etc). The project revolves around cities in European history and identity. A huge quantity of fictional and non-fictional AV works (from the end of the 19th century onwards) in their collections describe cities in all aspects, including physical transformation and social dynamics. Such material could prove of enormous value to scholars in different fields of study. I-Media-Cities plans integration and technical development work to push interoperability among 9 archives and generate two types of e-environments to be used by researchers and innovators for research and other creative purposes. This will allow new approaches to research in social sciences and unleash creativity, in new forms of delivery and consumption of that content which the creative industry would be able to propose for instance in tourism or in the cultural economy. To make that possible, the project relies on collaboration among three main components: a) FHI (Film Holding Institutions); b) research institutions in different areas of social sciences; c) expertise in exploitation processes of digital content. At the end of the project, we will deliver a digital content access platform (interoperable and multilingual), made available to a growing community of researchers and creatives Europe-wide to push the boundaries of what we can learn, through AV material on cities, on European history and identity. The legacy of I-Media-Cities will be a new model for research on digital sources (applicable also to other subject areas), plus appropriate exploitation plans to consolidate and expand the platform into the European reference initiative on AV digital content.