The PharmaLedger project will create a blockchain-based framework for the efficient digitization of the healthcare industry. The goal of the project is to provide a widely trusted platform that will support the design and adoption of blockchain-enabled healthcare solutions while accelerating delivery of innovation that will benefit the entire ecosystem, from manufacturers to patients. PharmaLedger will serve as a single source of truth for the healthcare ecosystem and will be designed for efficient decentralized governance, wide adoption by the stakeholders of the ecosystem, compliance with extant and emerging standards and regulation, and end-to-end connectivity and interoperability. Sustainability of the platform will be ensured by leveraging existing, successful blockchain technologies; open source reference implementation; and a fully documented, actionable methodology for evolutionary digitization of the healthcare industry. The project will address the key challenges of the healthcare ecosystem through prioritized delivery of applications and validation of business use cases, including but not be limited to end-to-end product tracking for combating counterfeit medicines and medical supplies; supply chain integrity; efficiency of recruitment and submission in clinical trials; and machine-learning health data marketplaces. The platform will support integrated use of medical devices across the use cases. The PharmaLedger project brings together 28 partners from 10 EU Member States, including 11 large pharmaceutical companies; highly innovative technology SMEs specializing in blockchain development, security, privacy and business intelligence; universities and research institutes specializing in pharmacoeconomic analysis, research of patient requirements, big data analytics and electronic health records; leading clinical trials companies; supply chain partners; patient representatives; and leading healthcare service providers.

Title : Cyber Security for Cross Domain Reliable Dependable Automated Systems. Goal : SECREDAS aims to develop and validate multi-domain architecting methodologies, reference architectures & components for autonomous systems, combining high security and privacy protection while preserving functional-safety and operational performance.

KYKLOS 4.0 will demonstrate, in a realistic, measurable, and replicable way the transformative effects that CPS, PLM, LCA, AR and AI technologies and methodologies will have to the Circular Manufacturing (CM)Framework. To this end, KYKLOS 4.0 will (1) perform large-scale piloting in 7 pilots to demonstrate the technical, environmental and economic viability of KYKLOS 4.0 Ecosystem to reshape intra-factory processes and services, (2) show KYKLOS 4.0 value in terms of operational efficiency improvements by at least 15%, (3) deliver resources reusable solutions (second use of material, part and components reuse) for the whole manufacturing sectors, (4) ensure scalability for future scale of novel CM technologies and services at least at the level of year 2024, (5) engage over 100 key European industry actors, (through open calls and workshops) (6) transfer knowledge and technology to increase use of KYKLOS 4.0 Ecosystem to at least 50%, (7) strengthen the position of EU CM technologies providers and sector fostering a market share of up to 12% (8) pursue a strong plan for sustainability by incubating at least 3 post-project replication sites, (9) mobilize additional sector investments of at least 6 times the EC contribution. Bringing together knowledge and solutions of major European CPS, PLM, LCA and AI technology providers together with the competence and experience of key European industry players in the CM domain, KYKLOS 4.0 will demonstrate a measurable increase of KYKLOS 4.0 Ecosystem penetration in CM market, reduction of environmental impact due to the reduce of the use of fossil fuels and raw materials and impact in seven pilot domains, which cover areas of major importance for the CM sector in EuropeA unique characteristic of KYKLOS 4.0 is that all CM related technologies, sectors and stakeholders together with their relevant expertise are covered. Thereby, the delivered by KYKLOS 4.0 are relevant for the whole manufacturing sector and market in Europe.

Hospitals and care centres are prime targets for cyber criminals, especially concerning data theft, denial-of-service and ransomware. This reflects the need of Healthcare Institutions for a Holistic Cyber Security vulnerability assessment toolkit, that will be able to proactively assess and mitigate cyber-security threats known or unknown, imposed by devices and services within a corporate ecosystem. SPHINX aims to introduce a Universal Cyber Security Toolkit, thus enhancing the cyber protection of Health IT Ecosystem and ensuring the patient data privacy and integrity. SPHINX toolkit will provide an automated zero-touch device and service verification toolkit that will be easily adapted or embedded on existing, medical, clinical or health available infrastructures, whereas a user/admin will be able to choose from a number of available security services through SPHINX cyber security toolkit. The SPHINX toolkit will enable service providers to specify complete services and sell or advertise these through a secure and easy to use interface. SPHINX Toolkit will be validated through pan-European demonstrations in three different scenarios. The operational properties of the proposed cyber-security ecosystem and overall solution will be validated and evaluated against performance, effectiveness and usability indicators at three different countries (Romania, Portugal and Greece). Hospitals, care centers and device manufacturers participating in the project’s pilots will deploy and evaluate the solution at business as usual and emergency situations across various use case scenarios.