The AquaticPollutants proposal responds to the Horizon 2020 (H2020) Societal Challenge 5 SC 5 21-2019-2020: Risks posed to human health and the environment by pollutants and pathogens present in water resources. AquaticPollutants aims at pooling resources from the 32 participating national and regional research programme owners / managers of 26 countries to implement a joint call for proposals (with EU co-funding). One of the most serious risks for freshwater and marine ecosystems and consequently human health derives from the occurrence of emerging pollutants and pathogens, especially antimicrobial resistant bacteria, in the environment. To face this challenge in a comprehensive way and to provide multidisciplinary solutions for a safe and clean aquatic ecosystems (freshwater, groundwater, marine) this ERA-NET Cofund is carried out as a collaboration between three Joint Programming Initiatives (JPIs): Water JPI “Water Challenges for a Changing World”, JPI Oceans “Healthy and Productive Seas and Oceans” and JPI AMR “On Antimicrobial Resistance”. The topic of the ERA-NET Cofund aims to deliver on priorities identified in the Research Agendas of the three JPIs. The overall objective is to strengthen the European Research Area (ERA) in the field of clean and healthy aquatic ecosystems and to leverage untapped potential in the collaboration between the freshwater, marine and health research areas. Moreover, AquaticPollutants includes 9 organizations from associated and third countries in an effort to reinforce and expand international cooperation. With new instruments in the Additional Activities the implementation of the co-funded call will be further supported and the cooperation of Water JPI, JPI Oceans and JPI AMR will be strengthened. It is envisaged to generate an increased visibility of the topic at European and international level and a stronger alignment of the three JPIs.