POCITYF supports the Lighthouse cities of Evora (PT) and Alkmaar (NL) and their Fellow cities Granada (ES), Bari (ΙΤ), Celje (SI), Ujpest (HU), Ioannina (GR) and Hvidovre (DK) to address their urgent need to deliver positive energy blocks and districts in their cities, towards rendering their mixed urban environment (also including the case of cultural protected buildings) into cheaper, better accessible, healthier and more reliable. By demonstrating in overall 10 integrated solutions (ISs), comprising 73 individual innovative elements (technologies, tools, methods), rooted under existing City Information Platforms (CIPs), POCITYF quantifies their value, and connects interests of many different stakeholders in innovative business models, allowing for upscale and replication of those solutions in a form of a validated roadmap for sustainable cities across Europe and world-wide. To achieve this, POCITYF works along 4 Energy Transition Tracks (ETTs), encompassing the ISs according to the role each one serves for. ETT#1 focuses on the examination and application of ISs transforming existing and new building stock into Energy Positive, while ETT#2 focuses on the application of a) grid flexibility strategies and b) storage systems, supported by DSM platforms for optimizing energy flows to maximize self-consumption and reduce grid stress. ETT#3 with its merit of innovation offers the integration of e-Mobility to as well promote the decarbonisation of the mobility sector. The 3 ETTs under the coordination of ETT#4, which links existing CIPs with innovative apps and other instruments, offers inclusive and holistic services for interdisciplinary citizen engagement and co-creation of them with the city stakeholders and industry, towards the development of each city’s own bold city-vision up to 2050. Through POCITYF the two LHs will achieve a local RES penetration of 16.2 GWh/y, energy savings of 2.32 GWh/y and an emission reduction of 9,743 tons CO2eq/y within their districts.