Organisations across the sectors significantly benefit from digital transformation to support evolving business models, services and customer experience. Despite the benefits of digital infrastructure adoption, there are numerous security challenges that could pose any digital disruption and risks for the critical service delivery and overall business continuity. There is a need to understand the overall digital infrastructure context and analyse and predict the possible threats and incidents in real-time so that quick and accurate responses can be taken into consideration for ensuring resilience of service delivery. Additionally, collaborative response and sharing of threat intelligence information is necessary to create overall awareness and increase the response capability of all stakeholders within the ecosystem. CyberSecDome will integrate advanced virtuality reality (VR) to extend the capability of the security solutions aiming to enhance security, privacy and resilience of the Digital Infrastructure. The project will consider AI-enabled security solutions to provide a better prediction of cybersecurity threats and related risks towards an efficient and dynamic incident management and optimise collaborative response among the stakeholders within the Digital Infrastructure ecosystem. CyberSecDome project is built on a collaboration of 15 organisations from 6 EU member states (IT, DE, IE, SE, EL, CY) and 2 affiliated countries (UK, CH), which is composed by 5 industrial partners, 6 scientific partners and 5 SMEs. The project will be coordinate by MAGGIOLI SPA.

CONSENTIS is geared to alleviate the challenges posed by personal data sharing towards the implementation of EU regulations and strategic initiatives like eIDAS, EU Data Spaces and GDPR. It introduces a novel framework which offers Self-Sovereign Identity and user-centric consent management solutions that enables users to (a) have full control over their personal data collection and usage and (b) provide informed consent through user-friendly interfaces and notifications. The proposed framework is agnostic to existing services and formats and guarantees high levels of protection avoiding potential legal uncertainty, through a continuous assessment mechanism for security, risk and legal aspects. CONSENTIS is an industry-oriented project, with SMEs and large companies covering more than 80% of the consortium and is built on a collaboration of 12 organisations from 9 EU member states and associated countries. The Consortium includes: 2 academic institutions, 8 SMEs and 2 large industry partners that bear strong interest and relevance to the project objectives and are highly committed in the delivery of scientific excellence and innovation in the fields of identity management and SSI, consent management, blockchain and smart contracts, user interfaces/user experience, cybersecurity and PETs, business and market impact and EU laws, policies and regulations for human rights and technology.

Technological advances in Information communication Technologies (ICT) as well as the digital transformation of complex systems have led to the development of novel networks, platforms and systems, which have, in turn, kick-started the realisation process for multi-faceted technological collaborations and data-driven workflows on a scale never seen before. Consequently, an integration process among the different layers of complex systems and services has been unfolding raising significant issues and challenges in its wake. Hence, the digital data and collaboration spaces are all predicated upon the realisation of what is known as the computing continuum, which is based on the integration of cloud, edge and Internet of Things (IoT). Nevertheless, this has given rise to significant security and privacy risks especially since it is about systems that involve a high number of entities and devices with different profiles, processing a vast amount of potentially sensitive info MEDIATE’s vision is to produce a robust technology, which will address the security and privacy attributes of the computing continuum. For this, it will put forth a complex architecture that is based on the concept of zero-trust and will assume a federated learning approach in order to perform security-based scrutinisation at all continuum levels. i.e. IoT, edge and cloud, using security models that can be updated, redistributed and reconfigured across it. The actual features of the MEDIATE framework will support major topic outcomes such as cybersecurity resilience through reconfiguration, vulnerabilities mitigation through cyber threat analysis, secure integration at the IoT level through software and hardware-based security sensors and trust and security for massive ecosystems through the use of federated learning-based orchestration. Moreover, it will feature AI-based tools for cyber threat intelligence that assist a decision support system and privacy policies for data and identity protection.

Current evidence from both randomized trials and real-world evidence studies suggests that older breast cancer patients derive clinical benefit from the addition of CDK 4/6-inhibitors to endocrine therapy but with higher risk for adverse events and treatment discontinuation compared to younger patients. The IMPORTANT project will design and conduct a pragmatic clinical study with a decentralised approach for older patients with advanced breast cancer aiming at high level of evidence (level I) with multi-layer results that can enable changes in current clinical practice. This study will be conducted across 6 (six) EU countries, and will include more than 500 female and male patients. The project will also perform a series of analyses over a) a wide range of clinical-relevant primary and secondary endpoints targeting to contribute to current clinical practice and b) the implementation of specific strategies aiming at more individualized treatment and follow-up approaches to a clinical trial setting that highly resembles real-world setting due to the trial's pragmatic design. The project will be developed in 60 months by a competitive consortium of 19 partners from 11 countries, which corresponds to a well-balanced structure, involving clinical sites, SMEs, universities and patient advocacy organizations. Despite the great diversity of entities within the proposal, IMPORTANT partners bring state-of-the-art complementary skills ensuring the ability of the consortium to successfully complete the proposed work.This action is part of the Cancer Mission cluster of projects on ‘Diagnosis and treatment’.

Security of open-source solutions in the business interconnected market (especially in IoT where a single product may include components from various Tier 1 or OEM manufacturers) is hard to assure. OEM SW/HW developers that employ open-source solutions must assume that any component provided by 3rd parties needs to be reassessed for security as there is not holistic security auditing/testing process to cover the full production line. The plethora of open-source HW/SW solutions on devices with constrained resources and no trusted environments leads to a considerably expanded threat landscape. The restricted execution environment reduces bootstrapping new devices in an IoT network and deploying/patching them securely; and the full DevSecOps of connected device open-source HW/SW must be reformulated offering security guarantees on the usage of open-source solutions. SecOPERA will provide a one stop hub for complex OSS/OSH solutions offering to designers, implementers, operators and open-source HW/SW developers the means to analyse, assess, secure/harden and share open-source solutions as these are integrated in an overall complex product within a networked connected environment. SecOPERA provides a framework supporting the open source DevSecOps lifecycle that comprises (i) a decomposition and security audit/testing engine that analyses open source solutions (OSS/OSH) (ii) an adaptation engine that debloats OSS/OSH code to remove unrelated open-source code and reduce the code attack surface; and a security enhancement process to harden the OSS/OSH solution (iii) an updating/patching mechanism so that the SecOPERA open-source flows remain secure even if their open-source code starting points are vulnerable. On top of that, SecOPERA hub provides (iv) an open-source repository for secure modules that is used in the security enhancement mechanism of open-source solutions; and (v) an open-source repository of security hardened OSS/OSH solutions and their security guarantees.