BACKGROUND: Adolescents are at particularly high risk for digital technology overuse, including in response to the COVID pandemic, and are therefore vulnerable for its potential harmful effects on mental health. Problematic usage of the internet (PUI) is thought to represent a marker of disrupted self-management, with major consequences for individual and societal health and wellbeing. AIM: Bootstrap brings together a multidisciplinary consortium aiming to initiate health and social policy and practice change designed to reduce the harmful effects of digitalization on mental health, particularly for young people. APPROACH: We will co-create a digital screening and assessment platform to understand which individuals are at-risk for developing PUI. Algorithm-based models will be used to predict which individual will benefit from which type of self-management intervention, and these preventative behavioral interventions will be tested for their (cost)effectiveness. Finally, we will develop a policy toolkit in co-design with stakeholders, to promote human digital rights accountability at the local, national, and European level. IMPACT: Bootstrap will provide unprecedented scientific knowledge on the psychological mechanisms underlying (risk for) PUI and potential interventions. Improved self-management and tools to optimize healthy internet usage will promote mental health and prevent mental ill health in adolescents, and contribute to reducing stigma. In addition, our policy toolkit will empower policy makers and private companies to (self)regulate with the intent to protect vulnerable groups. In the long run, Bootstrap will thus contribute to improving mental wellbeing across Europe and beyond.

The PACE research and training programme sits at the interface between basic science, technology and clinics, in order to unveil how humans control and adapt their movements in complex, naturalistic environments. Such a research agenda has major consequences for understanding how these movements are impacted by specific brain insults and how these impairments can be compensated for via new rehabilitation methods. Improving rehabilitation programmes for sensory and motor disabilities across the lifespan is a major societal challenge in western countries and many obstacles need to be overcome. To provide but one example, with regard to eye-hand coordination of upper limb movement remaining abilities are rarely assessed in stroke patients or sensory-disabled children and this impacts both prognostic estimation and rehabilitation. New technologies, such as robotics or virtual reality, provide an exciting change in perspective to transfer state-of-the-art knowledge from basic research on sensorimotor transformation into the clinical domain. To meet these societal challenges, it is crucial to train a new generation of early-stage researchers in a programme such as PACE where fundamental and applied/clinical research are effectively integrated via collaborative research, doctoral secondments and theoretical courses – in other words, one in which clinicians, neuroscientists, theoreticians and engineers can contribute around a well-defined problem: how humans acquire, lose and recover movement performance. With 8 academic, 1 clinical and 1 private beneficiaries, and 5 partner organizations (4 industrial, 1 in science communication), PACE structures a training and research programme that is both highly interdisciplinary and intersectoral. Our goal is to meet both fundamental and clinical well-identified challenges as well as preparing young scientists for future european research & development in the fields of human movement studies and rehabilitation medicine.