The theoretical understanding of human motor control and learning has a strong impact on the diagnosis and treatment of motor disorders, and vice versa. Recent progress has been made in the understanding of motor control and learning, particularly with respect to understanding the functional role of neuro-behavioural variability that is inherent to sensorimotor control. However, this progress has not yet been transferred appropriately into clinical therapy approaches. The goal of TReND is thus, to create a translational research network in motor disorder rehabilitation. The network will be highly interdisciplinary with doctoral and senior researchers from fundamental research areas (movement science, neuroscience, computer science), clinical practitioners (physical and occupational therapy, rehabilitation science, etc.) and partners from related industries. The overall aim is, to systematically translate recent theoretical and methodological advances in motor control and learning research into clinical practice to enhance clinical diagnosis and motor rehabilitation. More specific, we will investigate the functional role of variability in the sensorimotor coordination dynamics on behavioural and neurophysiological level in motor and mental disorders such as Stroke, Parkinson’s or Alzheimer’s disease. This will be addressed in three research objectives: 1. To investigate how different disorders affect the sensorimotor systems’ capability to exploit functional variability for stable and adaptive motor control; 2. To investigate how novel therapy concepts can enhance the capacity to exploit functional variability and treat motor disorders across different patient populations; and 3. To develop novel approaches to translate the knowledge gain from our fundamental research into clinical practice.

Current measures in healthcare systems are insufficient to reach the EU Green Deal goals. The social, economic and clinical consequences are significant. Reasons that current initiatives fall short include lack of awareness as to the problem, or potential solutions. There is complexity as to what process to choose, the low cost, the low carbon, the one that provides better care or the one which has the better social impact. The current system has insufficient investment in sustainable education, policy or research. Solutions work well in limited areas but are inefficient as a model for true systemic change. There is no agreed system of environmental foot printing in the health system and few partnerships with industry and patients to develop a truly sustainable system. Kidney care is a suited test case with its large resource footprint and well-defined care pathways. KitNewCare’s consortium will solve the problem with leading experts in kidney care, life cycle assessment methodology, education, dissemination and communication, health economics, and data management. KitNewCare will perform an EU-wide mapping of the sustainability landscape to reveal the hotspots across different clinical centres in each impact area. To locate solutions Quality Improvement Cycles will be utilised to analyse clinical pathways and industry innovations. KitNewCare will co-develop and pilot sustainable tools (such as the purposefully developed actionable dashboard, based on the 4-factor LCA model, which will monitor and benchmark the 4 different outcomes) innovative solutions, training, guidelines and recommendations as a proof of concept which can then be applied to the healthcare system; Our work will be informed by a stakeholder interaction and a Patient and Public Involvement programme to ensure proper design, uptake, dissemination and exploitation. This will enable decision makers and healthcare providers to reduce pollution, carbon emissions, and waste.