The future European research project, namely MSCA-Doctoral Network NanoF3Ind, on nanofluids comes in synergy to Cost Actions NanoUptake (2016-20), and Cost Innovator Grant Nanoconvex (2020-21). This previous efforts and works did not achieve the original goals of nanofluid development and applications in real industrial situations. Then, in line with these Actions, the ambition of this project is to train the new generation of researchers in this field for reaching a controlled use of nanofluids in real operating conditions from a global approach. This project will be performed from joint training and research activities involving, at starting point, scientific, technical and economic stakeholders in a common strategy. This project responds to current and future challenges about transition to a climate-neutral society by 2050, and sustainable economic developments for smart strategies to improve heat transfer and thermal storage. With this goal, the planned training programme, enabling innovative and responsible research, will be based on a complementary, pluridisciplinary and intersectoral network involving academic partners, European scientific consortia, industries (start-ups, SMEs, large groups, etc.), non-profit organizations, certification and standardisation agencies. This will make it possible to give a broad spectrum of skills and knowledge to future doctors, which can be completely transposed to other fields, thus guaranteeing them a strong employability at the end of the project, with entrepreneurial capacities, innovation, communication in a multidisciplinary international context. In a socially responsible research approach, they will be able to balance the challenges and tensions between science and industrial development, economic growth, public benefit and sustainable environment. The project will also strengthen Europe’s position and competitiveness in the field of nanofluids. Through the training excellence program developed by this project, it will be moving forward the current scientific knowledge to ensure the technological and normative development associated with the exploitation of nanofluids in energy systems, focusing on cooling and the use of solar energy.