
KRISS
4 Projects, page 1 of 1
Open Access Mandate for Publications and Research data assignment_turned_in Project2021 - 2024Partners:PURPOSEFUL IDIOTIKI KEFALAIOUXIKI ETAIREIA, PURPOSEFUL IDIOTIKI KEFALAIOUXIKI ETAIREIA, LAURENTIA TECHNOLOGIES, NANOCTR, ITENE +57 partnersPURPOSEFUL IDIOTIKI KEFALAIOUXIKI ETAIREIA,PURPOSEFUL IDIOTIKI KEFALAIOUXIKI ETAIREIA,LAURENTIA TECHNOLOGIES,NANOCTR,ITENE,Ca Foscari University of Venice,NANO POLYMER SOLUTIONS LLC,RCSI,Goa University,TECNALIA,CNR,RIVM,JRC,Ca Foscari University of Venice,Swansea University,ITENE,FUNDACION CIAC CENTRO DE INNOVACION ANDALUZ PARA LA SOSTENIBILIDAD EN LA CONSTRUCCION,ASU ABOR,WG,KRICT,Yordas GmbH,RCSI,ERS,CSIC,CNRS,EMPA,GREENDECISION SRL,ENCAPSULAE SL,AVANZARE,Mintek,SOLVAY,ENCAPSULAE SL,Mintek,NANOCTR,AVANZARE,ERS,Heriot-Watt University,KRISS,EMERGE,NANO POLYMER SOLUTIONS LLC,ASU ABOR,IOM,IOM,KRISS,FUNDACION CIAC CENTRO DE INNOVACION ANDALUZ PARA LA SOSTENIBILIDAD EN LA CONSTRUCCION,JRC,Duke University,OCSIAL EUROPE SARL,SOLVAY,SOLVAY CHIMIKA SINGLE MEMBER SOCIETE ANONYME,LAURENTIA TECHNOLOGIES,TEMAS SOLUTIONS GMBH,SOLVAY CHIMIKA SINGLE MEMBER SOCIETE ANONYME,NTUA,TEMAS SOLUTIONS GMBH,NTUA,TECNALIA,OCSIAL EUROPE SARL,EMERGE,Heriot-Watt University,KRICT,Yordas GmbHFunder: European Commission Project Code: 952924Overall Budget: 8,360,680 EURFunder Contribution: 6,521,350 EURThe main goal of SUNSHINE is to develop and implement S&SbD strategies for products enabled by multi-component (advanced) nanomaterials (MCNM), including high aspect-ratio nanomaterials (HARNs). To this end, the project will generate essential knowledge, tools and data on the exposure, hazard and functionality characteristics of these materials, especially those arising from their unique properties and interactions (e.g. mixture effects due to the multi-component nature of the materials). To facilitate the uptake and utilisation of the S&SbD strategies by industry, especially SMEs, we will deliver them as part of a user-friendly e-infrastructure designed to: (1) facilitate collaboration and information exchange between actors along nanotechnology supply chains (developers, producers, downstream users) to promote the development and implementation of S&SbD strategies for MCNM-based materials, products and processes; (2) support SMEs and large industries in the selection and application of simple, robust and cost-effective experimental, modelling and grouping/read-across approaches to acquire/generate the data needed to test the effectiveness of the S&SbD strategies; (3) enable risk-benefit analysis of the S&SbD-modified materials and products at each stage of the innovation process to ensure that they are safe for the human health and the environment without compromising their technical and/or commercial probability of success The S&SbD strategies that are effective in reducing the risks from MCNMs, while retaining product performance and economic viability, will be proposed for full scale industrial implementation. In addition, the project will contribute to Regulatory Preparedness by providing recommendations on improvement and adaptation of the current regulatory hazard, exposure and risk assessment guidance (e.g. REACH, Biocides, Consumer Products, Food and Feed, Medical Technologies) and standard guidelines (OECD, ISO, CEN) for MCNMs.
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For further information contact us at helpdesk@openaire.euOpen Access Mandate for Publications and Research data assignment_turned_in Project2019 - 2023Partners:UNC, UKCEH, TaY, Tampere University, UCD +40 partnersUNC,UKCEH,TaY,Tampere University,UCD,La Trobe University,JSU,Misvik Biology Oy,Biomax Informatics (Germany),Biomax Informatics (Germany),NIES,NRCWE NFA,Technology Strategy Board,UKCEH,EPSRC,QSAR LAB Sp. z o.o.,JSU,UC,NIES,Novamechanics,Novamechanics,NTUA,NILU,NRCWE NFA,TAMPERE UNIVERSITY,University of Birmingham,BAM,NATIONAL INSTITUTE FOR COMMUNICABLEDISEASES,UT,GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS,HANYANG UNIVERSITY,NATIONAL INSTITUTE FOR COMMUNICABLEDISEASES,NTUA,La Trobe University,Duke University,Stockholm University,HANYANG UNIVERSITY,UC,Misvik Biology Oy,UM,KRISS,KRISS,TO21 CO,UGOE,QSAR LAB Sp. z o.o.Funder: European Commission Project Code: 814572Overall Budget: 6,456,030 EURFunder Contribution: 6,098,530 EURNanoSolveIT will introduce a ground-breaking in silico Integrated Approach to Testing and Assessment (IATA) for the environmental health and safety of Nanomaterials (NM), implemented as a decision support system packaged as a standalone open software and a Cloud platform. NanoSolveIT will develop and deliver: (i) a reliable user friendly knowledge-based infrastructure for data hosting, sharing and exploitation, (ii) NM fingerprints, sets of nanodescriptors and properties that can be predictively linked to NM functionality, exposure and hazard, thereby supporting NM grouping, safe-by-design (SbD) and regulatory risk assessment (RA), (iii) innovative methodologies for NMs predictive (eco)toxicology underpinned by artificial intelligence and state-of-the-art in silico techniques, and, (iv) integration with multi-scale modelling, RA and governance frameworks developed in EU H2020 funded and in the forthcoming NMBP-13 project(s). NanoSolveIT will deliver a validated, sustainable, multi-scale nanoinformatics IATA, tested and demonstrated at TLR6 via OECD style IATA case studies, serving the needs of diverse stakeholders at each stage of the NMs value chain, for assessment of potential adverse effects of NM on human health and the environment. NanoSolveIT is fully aligned to the objectives of the EU-US Nanoinformactics Roadmap, addressing all 13 of its short, medium and long term milestones, and supports the recommendations of the EMMC on standards for developing material modelling software and OECD best practice. The NanoSolveIT consortium (EU and international partners) is the only grouping capable of delivering the ambitious goals of the NMBP-14-2018 call, since they have collectively driven most of the current progress in nanoinformatics: 81% of the nanoinormatics papers cited in the EU-US nanoinformatics roadmap had NanoSolveIT authors. NanoSolveIT will integrate across the consortium-wide modelling approaches to provide the IATA platform for in silico NMs RA.
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For further information contact us at helpdesk@openaire.euOpen Access Mandate for Publications and Research data assignment_turned_in Project2018 - 2021Partners:BASF SE, CNR, UCL, Swansea University, ERS +34 partnersBASF SE,CNR,UCL,Swansea University,ERS,UniPi,USC,Leiden University,MRC,EPSRC,NIA,INSPHERO,Misvik Biology Oy,University of Namur,HARVARD GLOBAL,BASF SE,RIVM,University of Exeter,INSPHERO,QSAR LAB Sp. z o.o.,IUF,NIA,UNIFR,NRCWE NFA,NRCWE NFA,IUF,USCL,HARVARD GLOBAL,Technology Strategy Board,ERS,QSAR LAB Sp. z o.o.,Misvik Biology Oy,DTU,Heriot-Watt University,KRISS,IOM,IOM,KRISS,Heriot-Watt UniversityFunder: European Commission Project Code: 760813Overall Budget: 13,108,300 EURFunder Contribution: 12,714,200 EURNanotechnology promises significant scientific, economic and societal benefits, but commercialization and growth are threatened by safety uncertainties. Classical hazard testing strategies to define the human and environmental health impact of engineered nanomaterials (ENM) commonly apply unrealistic acute, high-doses to models that do not reflect the in vivo environment. Furthermore, existing in vitro and in silico hazard detection methods are not accurately predictive. PATROLS addresses these limitations by establishing and standardizing the next generation of advanced safety assessment tools for improved prediction of the adverse effects caused by chronic ENM exposure in human and environmental systems. PATROLS will deliver: 1) physiologically representative multi-cellular in vitro 3D lung, gastrointestinal tract and liver models; 2) cross-species models integrating human and environmental safety testing; 3) innovative ecotoxicity bioassays in several organisms across a food chain; 4) robust in silico models for dosimetry, interspecies toxicity extrapolation and hazard prediction. ENM characterization under physiologically relevant experimental conditions will be integral to this realistic, exposure driven strategy. A systems biology approach will also be adopted to identify key events linked to adverse outcome pathways, informing mechanism-based endpoints associated with real-life ENM exposures. These objectives will be achieved by an international network of world-leading academic, governmental, industrial, SME, risk assessment agency and NGO partners. The innovative in vitro and in silico nanosafety testing tools developed by PATROLS will balance speed, cost and biological complexity, while reducing uncertainty via improved predictive power. The smart targeted testing approach will drive a paradigm shift in (eco)toxicology towards mechanism-based ENM hazard assessment to support policy development in human and environmental nanosafety regulatory frameworks.
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For further information contact us at helpdesk@openaire.euOpen Access Mandate for Publications and Research data assignment_turned_in Project2019 - 2022Partners:CSIC, INERIS, YOON IDEA LAB CO LTD, ECAMRICERT SRL, ECAMRICERT SRL +59 partnersCSIC,INERIS,YOON IDEA LAB CO LTD,ECAMRICERT SRL,ECAMRICERT SRL,NIA,FDHA,RIVM,AIRI,NIA,KI,BIONANONET FORSCHUNGSGESELLSCHAFT MBH,Cefic,AIRI,MBD,NWU,NATIONAL INSTITUTE FOR COMMUNICABLEDISEASES,DIALOG BASIS,BAuA,TEMAS AG TECHNOLOGY AND MANAGEMENT SERVICES,Cefic,TEMAS SOLUTIONS GMBH,EMPA,NRCWE NFA,SOLVAY,BAuA,INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS,MINISTERIE VAN INFRASTRUCTUUR EN WATERSTAAT,BIONANONET FORSCHUNGSGESELLSCHAFT MBH,BfR,ISS,KRICT,IDEA,CNRS,MBD,MINISTERIE VAN INFRASTRUCTUUR EN WATERSTAAT,NATIONAL INSTITUTE FOR COMMUNICABLEDISEASES,YOON IDEA LAB CO LTD,IDEA,NRCWE NFA,JRC,IRTA,AIST,AIST,DIALOG BASIS,KRISS,EMERGE,IOM,IOM,KRISS,JRC,Duke University,TNO,FDHA,TNO,University of Vienna,NWU,TEMAS AG TECHNOLOGY AND MANAGEMENT SERVICES,TEMAS SOLUTIONS GMBH,LEITAT,EMERGE,LEITAT,SOLVAY,KRICTFunder: European Commission Project Code: 814401Overall Budget: 9,407,380 EURFunder Contribution: 7,795,550 EURGov4Nano will design and establish a well-positioned and broadly supported Nano Risk Governance Council (NRGC). Organizing, connecting and engaging are key activities in Gov4Nano and its creation of a sustainable NRGC. Gov4Nano will develop an operational trans disciplinary Nano Risk Governance Model (NRGM) for nanotechnologies, building on an established governance framework developed by the International Risk Governance Council (IRGC). Engaging stakeholders (including regulators) to proactively address nano-specific safety and seek dialogue for joint activities. NRGC and its precursor project Gov4Nano will engage, in order to support these activities, with the broad variety of stakeholders across all relevant nano-disciplines (chemical, biocides, food and feed, pharma and medical devices and materials development) and draft a review on our knowledge progress over the last decade whilst initiating dialog. To boost the quality of the dialog it will create a platform for dialogues between stakeholders in a “trusted environment” inclusive of civil society. The NRGC core business is to coordinate, guide and harmonize in order to overcome the fragmentation of current knowledge, information and needs over various sectors and disciplines (workers, consumers/patients, environmental safety) and to prepare the transfer of this knowledge. To that end, the NRGC will be equipped with a self-sustainable NanoSafety Governance Portal (NSGP) consolidating state-of-the-art and progressive nanosafety governance tools including ones for dialogues and measuring risk perception. Major efforts will be towards requirements for data harmonization and data curation to be defined and laid down in guidance on obtaining harmonized and standardized quality-scored data collections promoting a big data approach for nano-toxicology. Research activities will be initiated for regulatory sound knowledge in support of harmonized (OECD) guidance for characterization and testing of nanomaterials.
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