Concept: NanoFASE will deliver an integrated Exposure Assessment Framework, including methods, parameter values, model and guidance that will allow Industry to assess the full diversity of industrial nano-enabled products to a standard acceptable in regulatory registrations. Methods to assess how use phases, waste streams and environmental compartments (air, soil, water biota) act as “reactors” in modifying and transporting ENMs will be developed and used to derive parameter values. Our nanospecific models will be integrated with the existing multi-media fate model SimpleBox4Nano for use in EUSES and also develop into a flexible multi-media model for risk assessment at different scales and complexities. Information on release form, transformation and transport processes for product relevant ENMs will allow grouping into Functional Fate Groups according to their “most probable” fate pathways as a contribution to safe-by-design based on fate. Methodology: Inventories of material release forms along the product value chain are established. We then study how released ENMs transform from initial reactive states to modified forms with lower energy states in which nanospecific properties may be lost. Transport studies assess material fluxes within/between compartments. The experimental work underpins models describing ENM transformation and transport. Open access is provided to the models suitable for incorporation into existing exposure assessment tools (e.g. SimpleBox4Nano) and for more detailed assessment. Framework completeness is validated by case studies. Impact: Identified links between ENM material properties and fate outcome (e.g. safe-by-design). Improved representation of nanospecific processes in existing key fate and exposure assessment tools (e.g. SimpleBox4Nano in EUSES). Contribution to standardization. GIS framework to support predictive assessment, catchment and point source management of ENM releases.

Emissions of the existing gasoline engines and brakes of the commercial vehicle fleets in Europe relate to health problems and death of annually >1,45 Mio. people. For the next decades, these vehicles will continue populating the roads, emitting PM/PN exhaust particles and toxic secondary emissions. For immediate reduction, retrofit solutions for tailpipe and brake emissions must be brought to TRL 8 and introduced to the market by 2025. Timing is crucial: Retrofits are transition technologies until full electrification of Europe’s transport fleet. Even beyond, brake retrofits play an important role in the electrified fleet. Quick wins in the reduction of the overall footprint of the existing fleets can be realised by using our 3 retrofits for tailpipe, brake and closed environments: 95% of PM2.5 and 80% of toxic secondary emissions using an innovative Gasoline Particle Filter, 60% of NOx exhaust emissions replacing the aged TWC by original equipment, 90% of the brake particles of long-lived road transport assets using a passive BDPF, 90% of particles in closed environments (bus stops, tunnels, metro stations) using a special designed and enhanced stationary air purifier. To create credible key messages for clients, citizens and policy, we perform lighthouse demo activities: 1) tailpipe retrofit: 1.000 vehicles in 2 climate zones (Germany + Israel) for 4 representative engine type families, 2) brake retrofit: Define emission fingerprints for the public transport of the cities of Valladolid, Ancona, Fermo and Sofia and > 35000 km lab testing on dynamometer and > 8000 km real driving, 3) air purifier retrofit for closed environments: 3 underground stations (Sofia, 2x Lisbon) with > 130000 commuters and Valladolid central bus depot with > 150 buses. For market preparation we will reach >4.000 citizens and policy makers from EU KOM level and >8 EU countries. We unite world leading industry, renowned scientific institutes and lighthouse demo sites in 8 European countries