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UPMC

UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6
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Web page: http://www.upmc.fr
Country: France
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299 Projects, page 1 of 60

  • EDPAH (Mechanisms of Exertional Dyspnea in Patients with Idiopathic Pulmonary Arterial Hypertension)

    assignment_turned_inProject2010 - 2012Partners:UPMC
    Funder: European Commission Project Code: 268396
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  • RETINAL-GENE-THERAPY (Overcoming translational barriers to gene therapy by novel vector design)

    assignment_turned_inProject2013 - 2017Partners:UPMC
    Funder: European Commission Project Code: 334130
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  • GENEPHYSCHEM (Spatio-temporal control of gene expression by physico-chemical means: from in vitro photocontrol to smart drug delivery)

    assignment_turned_inProject2011 - 2015Partners:UPMC
    Funder: European Commission Project Code: 258782
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  • BIOSHARE (Bacterial interaction in the oceans: Synergy among heterotrophic bacteria involved in the cycling of one-carbon compounds and its impact on the marine carbon cycle)

    assignment_turned_inProject2014 - 2017Partners:UPMC
    Funder: European Commission Project Code: 629378
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  • SACCAOR

    assignment_turned_inProjectFrom 2009Partners:UPMC
    Funder: French National Research Agency (ANR) Project Code: ANR-09-BLAN-0108
    Funder Contribution: 480,000 EUR

    In this proposal, two groups from a single partner (Institut Parisien de Chimie Moléculaire) at the University Pierre and Marie Curie-Paris 6 are joined together with strong complementary expertise. The proposed work lies in the field of asymmetric organometallic catalysis, from coordination chemisty to the applications in fine organic synthesis. Our approach consists in the development of new catalytic systems combining a cationic organometallic complex and a chiral counter-anion. We also plan the synthesis of new chiral ligands exhibiting centered-chirality (bis-sulfoxides ligands), or planar chirality based on new organometallic architectures built from Cp* linkers. Two important metal-catalyzed synthetic processes will be under scrutinity, namely the [2+2+2] cycloaddition and the recently developed electrophilic metal-catalyzed cycloisomerization of polyunsaturated systems. In addition, we envision theoretical computations for supporting these studies. This work will certainly generate important findings in coordination chemistry as well as applied homogeneous catalysis. We have all the required competences to conduct this project properly and successfully. Support from the ANR is crucial for us to start this project in a particularly competitive context.

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