FishEUTrust represents a consortium of twenty-two organizations from fourteen countries, pooling their expertise to defragment the current food system to ensure sustainability and deliver solutions for a transparent and traceable seafood supply chain necessary to promote high-end, pan-European farmed seafood. The innovation at the heart of FishEUTrust is integrating different actors into a digital platform that links technology providers, supply chain stakeholders, regulatory/policymakers and consumers. FishEUTrust will establish five Co-creation Living Labs (CLLs) in diverse environments: the Mediterranean Basin, the North Sea and the Atlantic Sea. These CLLs will enable user involvement in innovation and development processes and act as demonstrators for the consortium to test and validate digital and non-digital supply chain solutions. Examples include creating sustainable business models, exploiting IPR strategies for aquaculture, e.g., protecting cultural and culinary heritage, short food supply chains, exploiting underused fish species, and innovative engaging activities to stimulate/nudge behavioural change. It will also develop tools for maximizing trust by guaranteeing the quality, safety, and traceability of seafood products based on smart control systems (sensors), a suite of tools integrating metagenomics, genetic biomarkers, isotopic techniques, and digital technologies (labelling, Product Passport/Blockchain). These tools will be integrated into a single cutting-edge digital FishEUTrust platform that will apply the latest in artificial intelligence, data science and human-computer interactions. Finally, an integrated impact assessment and life cycle analysis will be performed to quantify the environmental footprint, health sustainability, and socio-economic benefits of FishEUTrust solutions. FishEUTrust will be supported by a comprehensive scientific, public, policymaker and industrial dissemination plan to communicate results to a broad audience.

The first and core objective of City4Age is to enable Ambient Assisted Cities or Age-friendly Cities, where the urban communities of elderly people living in Smart Cities are provided with a range of ICT tools and services that - in a completely unobtrusive manner - will improve the early detection of risks related to cognitive impairments and frailty while they are at home or in the move within the city. The second objective is to provide a range of associated tools and services which - with the appropriate interventions - will mitigate the detected risks. The final objective of C4A is to define a model which will provide sustainability and extensibility to the offered services and tools by addressing the unmet needs of the elderly population in terms of (i) detecting risks related to other health type problems, (ii) stimulating and providing incentives to remain active, involved and engaged, (iii) creating an ecosystem for multi-sided market by matching needs and their fulfillments, (iv) contributing to the design and operation of the ultimate Age-friendly City, where the city itself provides support for detecting risks and providing interventions to those affected by mild cognitive impairment (MCI) and frailty. To achieve these objectives City4Age builds on: - behavioural, sociological and clinical research on “frailty” and MCI in the elderly population; - state of art ICT technology (i) for “sensing” personal data and exposing them as linked open data, (ii) for designing the algorithms and the API’s to extract relevant behaviour changes and correlated risks, and (iii) for designing interventions to counter the risks, - stakeholder engagement in order to be driven by relevant user needs to ensure end-user acceptance.

Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS) are chronic diseases characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, cognitive). Patients have to manage alternated periods in hospital with care at home, experiencing a constant uncertainty regarding the timing of the disease acute phases and facing a considerable psychological and economic burden that also involves their caregivers. Clinicians, on the other hand, need tools able to support them in all the phases of the patient treatment, suggest personalized therapeutic decisions, indicate urgently needed interventions. Artificial Intelligence is the key to successfully satisfy these needs to: i) better describe disease mechanisms; ii) stratify patients according to their phenotype assessed all over the disease evolution; iii) predict disease progression in a probabilistic, time dependent fashion; iv) investigate the role of the environment; v) suggest interventions that can delay the progression of the disease. BRAINTEASER will integrate large clinical datasets with novel personal and environmental data collected using low-cost sensors and apps. Software and mobile apps will be designed embracing an agile and user-centred design approach, accounting for the technical, medical, psychological and societal needs of the specific users. BRAINTEASER will implement a system able to guarantee cybersecurity and data ownership to the patients; will provide quantitative evidence of benefits and effectiveness of using AI in health-care pathways implementing a proof-of-concept of its use in real clinical setting. Procedural requirements that support Software as Medical Device certification will be used involving clinicians and patients stakeholders and producing a set of recommendations for public health authorities. Results will be disseminated accordingly to an open science paradigm under the European Open Science Cloud initiative.

PROTECT-CHILD is a project that aims to improve the outcomes of rare pediatric transplant patients by integrating multiple sources of high-throughput data from registries, hospital-based and public repositories, complying with ongoing initiatives such as the European Open Science Cloud (EOSC) and the European Health Data Space (EHDS). The project focuses on the co-design of a secure and privacy-preserving infrastructure, harmonization of data standards, and creation of a public/private infrastructure for assembling large datasets to improve clinical outcomes. The project involves top-level expertise from a consortium of technology specialists, data standardization experts, and High-Performance Computing (HPC) centers, as well as clinical experts, legal experts, patients’ representatives, and policy makers. The project is aligned with EHDS and General Data Protection Regulation (GDPR) principles and aims to empower secure and compliant processing, analysis, and sharing of sensitive personal data, including genomics, while preserving data privacy and security.

HOLISDER introduces a Holistic Demand Response Optimization Framework that will enable significant energy costs reduction (~45%) at the consumer side, while introducing buildings as a major contributor to energy networks’ stability in response to network constraints and conditions. HOLISDER brings together a wide range of mature technologies and integrates them in an open and interoperable framework, comprising in a fully-fledged suite of tools addressing the needs of the whole DR value chain. In this way it will ensure consumer empowerment/transformation into active market players, through the deployment of a variety of implicit and hybrid DR schemes, supported by a variety of end-user applications for Personalized Informative Billing, Human-Centric Energy Management, Load Scheduling and Intelligent Controls, Self-consumption promotion and cost-effective storage, Predictive Maintenance, along with Context-Aware Automation. The backbone of HOLISDER project consists in an “open” and modular interoperability and data management framework that will enable open standards-based communication along the DR value chain. It will integrate two main commercial technologies/ products (JACE, EF-i) to ensure seamless information exchange, communication and operation on top of any Building and District EMS, as well as, Smart Home systems/devices. On the business side HOLISDER will focus on the definition of new business models for intermediaries and third parties (aggregators, energy retailers, facility managers, ESCOs) that will facilitate consumers’ involvement into energy markets by acting on their behalf and making the most out of their flexibility value. The HOLISDER framework will be validated in 4 large-scale demonstrators/pilot sites, located in Greece, UK, Finland and Serbia, incorporating diverse building types, heterogeneous home, building and district EMS and devices, a variety of energy carriers and spanning diverse climatic conditions, demographics and cultures.