Chemical technologies underpin almost every aspect of our lives, from the energy we use to the materials we rely on and the medications we take. The UK chemical industry generates £73.3 billion revenue and employs 161,000 highly skilled workers. It is highly diverse (therefore resilient) with SMEs and microbusinesses making up a remarkable 96% of the sector. Today's global chemicals industry is responsible for 10% of greenhouse gas (GHG) emissions and consumes 20% of oil and gas as carbon feedstock to make products. Decarbonisation (defossilisation) of the chemicals sector is, therefore, urgently required, but to do so presents major technical and societal challenges. New sustainable chemical technologies, enabled by new synthesis, catalysis, reaction engineering, digitalisation and sustainability assessment, are needed. In order to ensure that the UK develops a resource efficient, resilient and sustainable economy underpinned by chemical manufacturing, developments in chemical technologies must be closely informed by whole systems approaches to measure and minimise environmental footprints, understand supply chains and assess economic and technological viability, using techniques such as life cycle assessment and material flow analysis. Lack of access to experts in science and engineering with a holistic understanding of sustainable systems is widely and publicly recognised as a significant risk. It is therefore extremely timely to establish a new EPSRC CDT in Sustainable Chemical Technologies that fully integrates a whole systems approach to training and world leading research in an innovation-driven context. This CDT will train the next generation of leaders in sustainable chemical technologies with new skills to address the growing demand for highly skilled PhD graduates with the ability to develop and transfer sustainable practices into industry and society. The new CDT will be a unique and vibrant focus of innovative doctoral training in the UK by taking full advantage of two exciting new developments at Bath. First, the CDT will be embedded in our new Institute for Sustainability (IfS) which has evolved from the internationally leading Centre for Sustainable and Circular Technologies (CSCT) and which fully integrates whole systems research and sustainable chemical technologies - two world-leading research groupings at Bath - under one banner. Second, the CDT will operate in close partnership with our recently established Swindon-based Innovation Centre for Applied Sustainable Technologies (iCAST, www.iCAST.org.uk) a £17M partnership for the rapid translation of university research to provide a dynamic innovation-focused context for PhD training in the region. Our fresh and dynamic approach has been co-created with key industrial, research, training and civic partners who have indicated co-investment of over £17M of support. This unique partnership will ensure that a new generation of highly skilled, entrepreneurial, innovative PhD graduates is nurtured to be the leaders of tomorrow's green industrial revolution in the UK.

The EPSRC Centre for Doctoral Training in Water Infrastructure & Resilience II (WIRe II) builds upon the highly successful collaboration between three of the UK's centres of excellence in water research (Cranfield, Sheffield and Newcastle Universities). One of the foundations of a thriving civic community and economy is having secure, resilient and sustainable water resources and services that: (i) provide affordable and equitable access to water; (ii) deliver a safe drinking water supply; (iii) provide wastewater services that don't pollute the environment; (iv) ensure there is enough water to meet the increasing demands from multiple sectors; and (v) are net beneficial to the environment, while protecting critical infrastructure from the impacts of climate change. This is placed against a backdrop of increased levels of dissatisfaction and higher expectations from civic communities on their water services, multiple demands on water resources and adaptations required from the impacts of climate change. With the UK population expected to grow from 69 million to 79 million by 2050, water resources have never been under as much pressure. Recent assessments have shown that only 14% of English rivers have good ecological status and no river has good chemical status. Water companies have also been placed under significant public examination from recent well-publicised pollution incidents from storm overflows and restrictions in water, with expectations that the UK will need to save 4billion litres of water per day by 2050. A collaborative and interdisciplinary approach is therefore essential for securing more resilient and sustainable water systems. There is also an urgent demand for improved water management as we move into a more sustainable world - the requirement for suitably skilled specialists with the appropriate interdisciplinary skills has never been higher. In developing the case for WIRe II, we have brought together an important group of civic partners, including the water utilities (with representation from all nations of the UK, covering water and wastewater services for 90% of the UKs population), organisations from the energy sector working on net zero technologies that have significant water demand and/or wastewater streams, regulators and civic groups, consultancies who work across the water-energy nexus, and partnerships with UKCRIC and DAFNI for access to world leading facilities. The CDT will be a significant contributor to addressing a clear skills gap identified by our partners and provide a future blueprint for enhanced training in the sector. We urgently need research to understand whole water systems (catchment, treatment and distribution processes) to achieve stable, safe water delivery to customers and the return of water back to the environment for multiple beneficial purposes. Such complexity requires inter- and trans-disciplinary research and a critical mass of experts and outputs. Three interconnected research themes will be addressed in WIRe II that align with key civic priorities: Safe and sustainable water resources for all; A resource neutral water sector; and Adapting to climate change. The WIRe II training programme has been developed with our partners to ensure we develop talent with the skills, competencies, and creativeness required to meet the changing demands of the sector. Built around the principles of deep vertical and horizontal integration of cohorts, students will progress through the CDT by undertaking a common induction semester, an assessed taught programme, an inspiring transferable skills curriculum and an annual Summer Challenge, alongside opportunities for national and international placements. We have evolved the programme to deliver the transformative science needed to tackle the rapidly changing demands and challenges being faced across our water systems and to develop the future leaders in the water and allied sectors.

Wearable electronics like smart watches are popular gadgets, their value as biosensor is limited however as they are not directly interfaced with the skin. While body temperature, heart rate and blood oxygen content and important factors to evaluate the overall health of an individual, these parameters lack the information contained in biological metabolites excreted through sweat. The presence or fluctuation in concentration of many metabolites can be directly related to a medical condition. High glucose levels could be indicative of diabetes, whilst the presence of lactate would indicate fatigue and high cortisol, a steroid hormone, levels often pointing towards increased stress levels. This fellowship extension will focus on the integration of flexible and self-repairing organic semiconductors into skin-wearable biosensors for non-invasive health monitoring. The wearable sensors will be fully conformal, similar to a standard band aid, and robust enough to be worn directly on the skin. By carefully functionalising the active material, the organic semiconductor, we aim to achieve a high selectivity and sensitivity, able to record the minute changes of biological metabolites excreted through sweat on the skin. The realisation of such light weight and robust wearable sensors directly applied to the human skin, would make the continous monitoring of relevant biological metabolites a reality, opening new avenues for more cost-effective preventive healthcare and patient-centred care.

Our EPSRC CDT in Advanced Engineering for Personalised Surgery & Intervention will train a new generation of researchers for diverse engineering careers that deliver patient and economic impact through innovation in surgery & intervention. We will achieve this through cohort training that implements the strategy of the EPSRC by working across sectors (academia, industry, and NHS) to stimulate innovations by generating and exchanging knowledge. Surgery is recognised as an "indivisible, indispensable part of health care" but the NHS struggles to meet its rising demand. More than 10m UK patients underwent a surgical procedure in 2021, with a further 5m patients still requiring treatment due to the COVID-19 backlog. This level of activity, encompassing procedures such as tumour resection, reconstructive surgery, orthopaedics, assisted fertilisation, thrombectomy, and cardiovascular interventions, accounts for a staggering 10% of the healthcare budget, yet it is not always curative. Unfortunately, one third of all country-wide deaths occur within 90 days of surgery. The Department of Health and Social Care urges for "innovation and new technology", echoing the NHS Long Term Plan on digital transformation and personalised care. Our proposed CDT will contribute to this mission and deliver mission-inspired training in the EPSRC's Research Priority "Transforming Health and Healthcare". In addition to patient impact, engineering innovation in surgery and intervention has substantial economic potential. The UK is a leader in the development of such technology and the 3rd biggest contributor to Europe's c.150bn euros MedTech market (2021). The market's growth rate is substantial, e.g., an 11.4% (2021 - 2026) compound annual growth rate is predicted just for the submarket of interventional robotics. The engineering scientists required to enhance the UK's societal, scientific, and economic capacity must be expert researchers with the skills to create innovative solutions to surgical challenges, by carrying out research, for example, on micro-surgical robots for tumour resection, AI-assisted surgical training, novel materials and theranostic agents for "surgery without the knife", and predictive computational models to develop patient-specific surgical procedures. Crucially, they should be comfortable and effective in crossing disciplines while being deeply engaged with surgical teams to co-create technology solutions. They should understand the pathway from bench-to-bedside and possess an entrepreneurial mindset to bring their innovations to the market. Such researchers are currently scarce, making their training a key contributor to the success of the UK Government's "Build Back Better - our plan for growth" and UKRI's "five-year strategy". The cross-discipline collaboration of King's School of Biomedical Engineering & Imaging Sciences (BMEIS, host), Department of Engineering, and King's Health Partners (KHP), our Academic Health Science Centre, will create an engineering focused CDT that embeds students within three acute NHS Trusts. Our CDT brings together 50+ world-class supervisors whose grant portfolio (c.£150m) underpins the full spectrum of the CDT's activity, i.e., Smart Instruments & Active Implants, Surgical Data Science, and Patient-specific Modelling & Simulation. We will offer MRes/PhD training pathway (1+3), and direct PhD training pathway (0+4). All students, regardless of pathway, will benefit from continuous education modules which cover aspects of clinical translation and entrepreneurship (with King's Entrepreneurship Institute), as well as core value modules to foster a positive research culture. Our graduates will acquire an entrepreneurial mindset with skills in data science, fundamental AI, computational modelling, and surgical instrumentation and implants. Career paths will range from creating next generation medical innovators within academia and/or industry to MedTech start-up entrepreneurs.

The proposed EPSRC Centre for Doctoral Training in Sensor Technologies in an Uncertain World (Sensor CDT) will educate leaders who can effectively address the challenges of an increasingly uncertain, complex, and interconnected world. In recent years, society has faced a global pandemic, an energy crisis, and the consequences of war and the climate crisis. Sensor technologies play a vital role in addressing these challenges. They are essential tools for detecting changes in the world, protecting livelihoods, and improving well-being. Accurate sensory data are crucial for informing the public and enabling governments and policymakers to make evidence-based decisions. The new Sensor CDT is designed to train and inspire future sensor leaders with interdisciplinary and agile thinking skills to meet these challenges. Our students will learn to collaborate within and across cohorts, and co-create solutions with key stakeholders, including other scientists, industry partners, the third sector, and the public. The fully integrated 4-year Master + PhD program will be co-delivered by over 80 leading academics, over 25 industrial partners, and national research and policy agencies, and will cover the entire sensor value chain, from development over deployment and maintenance to end-of-life including middleware, and big data. Within the broader theme of uncertainty, we have identified three Focus Areas: I) Uncertainty in Sensory Data. According to the environmental sensor report published by UKRI in 2022, "data quality remains a major concern that hinders the widespread adoption of low-cost sensor technology". Through bespoke training in measurement science, statistical methods and AI, our students will learn to determine data quality and interpret imperfect, uncertain and constantly changing data. By acquiring hands-on design and prototyping skills and familiarising themselves with ubiquitous open technology platforms, they will learn how to construct more accurate and reliable sensors. II) Sensors in an Uncertain World. Environmental, economic and social uncertainties disproportionately impact low- and mid-income countries. Through collaboration with academic partners and policy agencies, the students will explore the impact of these interconnected uncertainties and pathways through which they can be mitigated by deploying low-cost sensor technologies. III) Uncertainty in Industry. UK industries deal with uncertainties in supply chains, variable process conditions and feedstocks, and they are subject to changing regulatory guidelines. Sensor data are critical to minimise the effect of such uncertainties on the quality of products and services. Through the provision of training in technical skills, systems thinking, leadership, and project management, our students will learn to innovate on rapidly changing timelines, and to work increasingly in collaboration and synergy with stakeholders in commerce and the public. Whilst prevention of future disasters is important, we recognise an increasing need to create resilience in a world facing rapid, often irreversible, change. Solutions must be co-created with society. The CDT will equip students with the confidence to collaborate across a range of fields, including arts and social sciences, skills that cannot be acquired in traditional, single student / single discipline PhD programmes. Finally, our programme will address a skills gap identified by UK industry and academia, who report a growing problem in recruiting suitably qualified candidates with the skills, disciplinary breadth and leadership qualities needed to drive innovation in the sensor field. In the UK alone, the sensor market contributes to ~£6bn in exports, underpins ~70,000 jobs, and connects to a global market estimated to reach £500bn in 2032 (Sensors KTN). Providing the skilled talent for the UK to succeed in this rapidly growing and competitive sector is a crucial goal of our programme.