The objective of SCALE-it is to increase the availability, accessibility and adoption of cost-effective alternatives to contentious inputs and thus reduce the dependency of organic farming on (a) critical plant protection products, (b) manure from conventional farms, (c) antibiotics and anthelmintics, and (d) synthetic and GMO derived vitamins. SCALE-it follows a multi-actor approach involving partners from the whole organic value chain (farmers, farmers' associations, advisors, veterinarians, researchers, industry, consumers). It builds on previous projects and takes forward most alternatives (products, tools, holistic methods) to TRL7-9. Less advanced alternatives are developed further by (i) reviewing information and (ii) testing experimentally before including them in demonstration trials under organic conditions. Local Ambassadors with an outstanding outreach capacity in the organic farming community lead over 65 trials across Europe, organising local dissemination events, and generating novel data for the environmental and economic impact assessments. SCALE-it supports companies to establish roadmaps for upscaling alternatives, registration and IP protection. Farmers’ and consumers’ acceptance of alternatives is analysed. SCALE-it is well placed to moderate the development of implementable rules on the use of inputs in organic farming and provide support to policy development via national and international multi-actor activities. Targeted dissemination materials and training packages will be developed. SCALE-it results will reduce the use of contentious inputs and increase the use of their alternatives in organic (and non-organic) production by (a) increasing the availability and knowledge on best use of alternatives, (b) creating decision making and (c) advisory tools and (d) showcasing the alternatives. It supports the transition to sustainable farming systems in line with the F2F strategy, promoting fair, healthy and environmentally-friendly food systems.