To deliver on our European 6G vision for the 2030s, and to tackle opportunities and challenges of increasing magnitude, e.g., sustainability, trustworthiness, green deal efficiency, digital inclusion, there is need for a flagship project, towards the elaboration of a holistic 6G network platform and system. To fill this need, Hexa-X-II is proposed with the ambition of being this flagship project, and of inspiring the world for digital transformation through novel 6G services. Hexa-X-II will work, beyond enabler-oriented research, to optimized systemization, early validation, and proof-of-concept; work will progress from the 6G key enablers that connect the human, physical, and digital worlds, as explored in Hexa-X, to advanced technology readiness levels, including key aspects of modules / protocols / interfaces / data. Hexa-X II includes: (a) the provision of advanced / refined use cases, services, and requirements, ensuring value for society; (b) the delivery of the 6G platform blueprint, which will encompass enhanced connectivity for 6G services, mechanisms realizing the “networks beyond communications” vision (sensing, computing, trustworthy AI), efficient network management schemes; (c) the realization of extended validation at system and component level; (d) actions for global impact, while assuring strategic autonomy in critical areas for the EU. Europe is starting from the pole position with 6G research and is leading wireless network technologies today. Now is the time to leverage our joint research ambition with a flagship project that will lead the R&D effort towards end-to-end systemization and validation. The Hexa-X-II flagship is a unique effort and a holistic vision, of a 6G system of integrated technology enablers, which accomplish “beyond the sum of the parts”, and of a “network beyond communications” platform for disruptive economic / environmental / societal impact; these are vital for establishing the European 6G technology leadership!