The project unites three clusters: Estonian ICT Cluster as coordinator (legal entity: Estonian Association of Information Technology and Telecommunications; representing a Strong Innovator region and bridging the project with three large European networks, the European Digital SME Alliance, DIGITALEUROPE and ITS Nationals), MOBINOV automotive cluster from Portugal (representing a Moderate Innovator region and leveraging outreach of the project to other EU mobility and automotive clusters via the European Automotive Cluster Network) and Georgian ICT Cluster (representing a Modest Innovator region and linking the project with the Georgian Digital Transformation Consortium and other national innovation actors). The consortium also includes Baltic Innovation Agency (Estonia), an experienced innovation management company and representative of Enterprise Europe Network in the project. Together the partners will act as a driving force to build strategic collaboration between their ecosystems and encourage the involvement of more diverse innovation stakeholders (with a specific focus on stronger involvement of woman entrepreneurs) as well as building contacts with innovation ecosystems from other countries. The main aim of INFIMO is to foster the development of interconnected and inclusive innovation ecosystems via a strategic collaboration between clusters and a variety of innovation actors, focused on using ICT for digital and twin transition in various economic sectors aligned with the industry 5.0 (and emerging industry 6.0) framework. Related to this, INFIMO develops and validates two collaboration models: (1) a generic model supporting digitalisation and sustainability in a variety of economic sectors; (2) An advanced model facilitating the twin transition and higher competitiveness in the mobility sector based on joint RD&I pilots as well as an open innovation competition. Both models can be used to in a wide range of European innovation ecosystems in the future.