The integration of edge computing, advanced 5G connectivity, and decentralized processing drives the widespread deployment of private edge ecosystems capable to reshape numerous industry sectors. However, unlocking the full potentials of edge-level intelligent management requires concerted efforts in platform development and cross-sector collaboration. COP-PILOT, develops a Collaborative Open Platform framework geared towards orchestrating end-to-end services across diverse industry domains. In crafting an open platform, COP-PILOT provides a flexible solution designed to effectively manage various industry sectors while ensuring robust security, automation, and intelligence features. Regarding interoperability, the framework seamlessly integrates with underlying technologies, ranging from IoT platforms to core infrastructure, facilitating collaboration across the compute continuum. Furthermore, COP-PILOT empowers the development of advanced cross-sector applications by offering support for cutting-edge network services, thereby enabling heightened security, resource management, and automation capabilities. The implementation strategy revolves around two primary directions: enabling platform implementation and real environment integration. For the former, COP-PILOT adopts a modular orchestration approach, simplifying the onboarding of complex applications through a user-friendly generative AI interface. This approach includes integration with multi-tiered data processing, policy-driven optimization, and dynamic reasoning capabilities, ensuring alignment with prevailing industry standards. In terms of real environment integration, the platform is deployed across four large piloting clusters, addressing a diverse array of edge paradigms. These use cases span across energy, smart city, agriculture, and industrial manufacturing sectors, fostering the development of cross-sector applications in mobility, logistics, and resource management.