SUPREME aims at optimizing powder metallurgy processes throughout the supply chain. It will focus on a combination of fast-growing industrial production routes and advanced ferrous and non-ferrous metals. By offering more integrated, flexible and sustainable processes for powders manufacturing and metallic parts fabrication, SUPREME enables the reduction of the raw material resources (minerals, metal powder, gas and water) losses while improving energy efficiency, production rate and CO2 emissions, into sustainable processes and towards a circular economy. To achieve this goal, an ambitious cross-sectorial integration and optimization has been designed between several powder metallurgy processes: gas and water atomization as well as ball milling for metal powder production, additive manufacturing and near-net shape technologies for end-parts fabrication. Quality and process control will be developed to monitor KPI, based on eco-innovation approach, to demonstrate the optimization of material and energy use. 4 demonstrators will be proposed at each step of the value chain in real industrial setting and ready for business exploitation at TRL 7: mineral concentration, metal powder manufacturing, metal part manufacturing and end-product that will validate a global optimization of more than 25% on material yield losses, more than 10% on energy efficiency, more than 10% on production rate and beyond 30% of CO2 emissions. SUPREME has gathered an outstanding consortium of 17 partners from 8 countries, represented by 11 companies including 6 SMEs that will ensure a successful implementation towards market applications. 5 applications sectors are targeted: automotive, aeronautics, cutting tools, molding tools and medical. The process key differentiation advantages will bring modularity, flexibility and sustainability to powder metallurgy and will reduce the total cost breakdown of these technologies, boosting their adoption by industry.