Latin American countries face the challenge of transforming into knowledge-based societies. Adaptation to these challenges has prompted universities to revise their traditional functions and assume a proactive role in contributing to economic and social development of the society. TETRIS general objective is to enhance to building trust in academic research and in university-industry collaboration by improving the effectiveness of Technology Transfer activities at the Partner Country HEIs. The project aims to improve the level of institutionalization of the ‘third mission’ of the partner universities from Latin America. The development of innovation schemes at institutional level will facilitate and encourage university-industry partnerships. More systematic efforts are required to unlock the potential of research and innovation results. The project will address the regional priority by a carefully designed set of capacity building actions targeting two intervention areas: i) institutional policies on IP and technology transfer and ii) institutional set-up and mechanisms for technology transfer and innovation. The project has three phases: the initial phase is about detailed assessment of Technology Transfer performance and will result in individual development needs. The next phase is the design and development of organisational, operational models and technology transfer mechanisms. The last phase is dedicated to the implementation: universities will adopt and implement elements of the previously developed models that suits best the institutional strategy and capability. Upskilling professionals and improving the knowledge transfer function together will allow them to actively engage with the innovation ecosystem and will have a multiplier effect on research and education. The project will contribute to increase openness and transparency by developing a technology transfer innovation scheme.