The economic crisis and pandemic in South Mediterranean and sub-Saharan countries have put the HEIs in a challenge to accommodate for the new requirements of online teaching. The RL4Eng project aims to improve the quality of higher education in third countries and make it more relevant into the today’s digital transformation world through establishing Remote and Virtual Laboratories for Teaching and Training Engineering Students to modernize the current teaching approaches and improve the digital and entrepreneurial capacities of both students and teachers in South Mediterranean and Sub-Saharan HEIs. The project’s contribution to the priorities of the call includes the digital transformation under which digital education is the focus of the project. Online teaching for laboratories has been implemented in EU countries with successful outcomes. The involvement of different European Universities will help integrate good practices and minimise potential risks in implementing the RL4Eng project. South Mediterranean HEIs have identified the necessity of training with numerous initiatives available in the European system. Few Research is available on the effective delivery of remote labs and take-home labs. The project involves several workpackages in efforts made to elevate the knowledge of remote labs and take-home labs in the partners institutions via capacity building for students, staff and faculty and share of experiences. A remote lab will be established in each country of the partners institutions and a take-home lab will be established in each HEI of the partner countries. The very nature of remote labs, and take-home labs makes them sustainable and easily scalable as they becomes part of the university structure and receives part of its budget. Moreover, the nature of the remote labs makes them sustainable as they are accessible from everywhere and could be used for both teaching and for research.