The Avon Longitudinal Study of Parents and Children: An international resource for population genomics and lifecourse epidemiology. Core Programme Support 2011-2015 and Core programme support 2014-2019
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For over 20 years Children of the 90s (or ALSPAC) has charted the health of 14,500 parents and children. Now in its third decade it has started to study the next generation, the children of the Children of the 90s. The study is unequalled by other population studies because of the breadth and depth of information it holds on participants from before birth over 20 years ago through to the present day. It is internationally renowned and used by researchers worldwide. The data allow researchers to study key periods of development, how certain conditions develop and change over time and are passed (or not) from one generation to the next, and how health is affected by the interplay between genes and other factors like smoking, where people live and the job they do. Our goals are to ensure the resource remains sustainable and open to researchers to use, and that participants remain engaged. We will continue to gather information from the original children through clinical assessments, questionnaires and record linkage, and will be recruiting and gathering data on the children of the children as well as merging genetic data and enhancing research in the exciting new field of epigenomics.
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