Seasonal Thermal Energy Storage (STES) is widely researched for having benefits in that it utilizes excess energy which would be wasted otherwise. The purpose of this study is to analyze energy efficiency of seasonal solar thermal energy system as heating system for greenhouses and compare it with conventional variable air volume (VAV) heating system. Greenhouse was chosen as a simulation model because it requires constant and stable heating through winter season to extend growing season and also because greenhouse can provide enough area to install solar collectors and heat storage tanks. The proposed seasonal solar thermal energy storage system consists of solar thermal collector, fully mixed heat storage tank, and VAV system. Energy simulation was conducted in two steps: heat storing in summer season, and heating in winter season. For greenhouses with area sizing 1600 m2, solar thermal collector of 1250 m2 and heat storage tank of 2000 m3 were designed. TRNSYS 17 and engineering equation solver (EES) were implemented for simulation and calculation of the systems thermal data. Simulation results showed the tank water temperature rising up to optimal temperature (95 oC) before heating season, and STES heating contributed to 55% of total heating load. Consequently, 30% of total heating cost was cut down showing energy efficiency of seasonal solar thermal energy storage system.