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A Polymer Blend Substrate for Skeletal Muscle Cells Alignment and Photostimulation

handle: 10281/315601 , 11583/2985584 , 11311/1167061
Substrate engineering for steering cell growth is a wide and well‐established area of research in the field of modern biotechnology. Here we introduce a micromachining technique to pattern an inert and transparent polymer matrix blended with a photoactive polymer. We demonstrate that the obtained scaffold combines the capability to align with that to photostimulate living cells. This technology can open up new and promising applications, especially where cell alignment is required to trigger specific biological functions, e.g., generate powerful and efficient muscle contractions following an external stimulus.
cell alignment, geneless optostimulation, organic semiconductors, photostimulation, photothermal effect, FOS: Physical sciences, QC350-467, Optics. Light, Condensed Matter - Soft Condensed Matter, cell alignment, TA1501-1820, photostimulation, Soft Condensed Matter (cond-mat.soft), Applied optics. Photonics, photothermal effect, geneless optostimulation, organic semiconductors
cell alignment, geneless optostimulation, organic semiconductors, photostimulation, photothermal effect, FOS: Physical sciences, QC350-467, Optics. Light, Condensed Matter - Soft Condensed Matter, cell alignment, TA1501-1820, photostimulation, Soft Condensed Matter (cond-mat.soft), Applied optics. Photonics, photothermal effect, geneless optostimulation, organic semiconductors
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