In the Mediterranean area most of the public authorities need to enhance their institutional capacity in the field of Energy Efficiency (EE) and use of Renewable Energy Sources (RES) in order to contribute to the Energy Performance of Buildings and the Energy Efficiency Directives, developing solutions suited to various regional contexts. The PrioritEE project, funded by the Interreg MED programme, aims at reinforcing the capacities of public administrations in selecting and implementing eco-friendly and cost-effective energy planning measures. This paper aims to describe the main efforts carried out by local public authorities and professional institutions from five MED countries (Italy, Portugal, Spain, Greece and Croatia) in order to reduce energy consumption and prioritize EE investments in Municipal Public Buildings (MPBs). In particular, it focuses on the methodological framework describing the main components of the proposed toolbox, the main objectives and expected outcomes but also the current achievements and the way forward.