This is the companion paper of part I of DeST overview. DeST was developed as a building simulation tool with the aim of benefiting both design of and research on building energy efficiency. During its development, DeST has been applied to many projects, development of building regulations, and research. This paper gives examples of several areas in which DeST has been applied, including building design consultation, building commissioning, building energy conservation assessment, a building energy labeling system, and scientific research. Examples from a demonstration building are presented to demonstrate the entire process of aiding design with DeST. Additional projects and regulations are also mentioned to introduce other applications of DeST.