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Neuroscience Letters
Article . 1991 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
Neuroscience Letters
Article . 1991
Data sources: Europe PubMed Central
Neuroscience Letters
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Ethanol potentiation of 5-HT3 receptor-mediated ion current in NCB-20 neuroblastoma cells

descriptionPublicationkeyboard_double_arrow_right Article , Journal 01 Jan 1991Publisher:Elsevier BVJournal:Neuroscience Letters, volume 122, pages 57-60 (issn: 0304-3940, Copyright policy )
Authors: David M. Lovinger;

doi: 10.1016/0304-3940(91)90192-v

pmid: 1711659

Ethanol potentiation of 5-HT3 receptor-mediated ion current in NCB-20 neuroblastoma cells

Abstract

The effect of acute ethanol (EtOH) exposure on 5-HT3 receptor-mediated ion current was examined in whole-cell patch-clamp recordings from NCB-20 neuroblastoma cells. The physiologic and pharmacologic properties of 5-HT-activated ion current in NCB-20 cells indicated that it was mediated by 5-HT3 receptors. EtOH potentiated 5-HT3 receptor-mediated current in a concentration-dependent manner at concentrations (25-100 mM) which are achieved during EtOH intoxication in vivo.

Related Organizations
Keywords

Neuroblastoma, Ethanol, Receptors, Serotonin, Tumor Cells, Cultured, Ion Channels

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 113
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
113
Average
Top 10%
Top 1%
Related to Research communities
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