In this study, fuel ethanol production from food waste using enzymatic hydrolysis and fermentation was evaluated from techno-economic viewpoint. The plant was designed with a capacity of 10 t/d food waste and a lifetime of 15-year. The total capital cost, annual operation cost and annual net profits of the plant were US$ 367,552, US$ 155,959 and US$ 74,995.57, respectively. The plant was economically viable as long as the internal rate of return remained below 29.8%. The shortest payback time was 5 years with discount rate of 5%. The price of fuel ethanol and food waste treatment fee were the most important variables for the economic performance of the plant by sensitivity analysis. This work could provide the basic knowledge for techno-economic analysis of food waste treatment and promote the industrial production of fuel ethanol.