Abstract Building energy performance is often inadequate given design goals. While different types of assessment methods exist, they either do not consider design goals and/or are not general enough to integrate new and innovative energy concepts. Furthermore, existing assessment methods focus mostly on the building and system level while ignoring more detailed data. With the availability and affordability of more detailed measured data, the increased number of measured data points requires a structure to organize these data. This paper presents the Energy Performance Comparison Methodology (EPCM), which enables the identification of performance problems based on a comparison of measured data and simulated data representing design goals. The EPCM is based on an interlinked building object hierarchy that structures the detailed performance data from a spatial and mechanical perspective. This research is developed and tested on multiple case studies that provide real-life context and more generality compared to single case studies.