With climate change leading to more frequent, more intense, and longer durations of extreme weather events such as heat waves and cold snaps, it is essential to maintain safe indoor environmental conditions for occupants during such events, which may coincide with, or even cause, power outages that expose residents to health risks. Analyzing the impacts of extreme weather events on the thermal resilience of buildings can help stakeholders (including occupants) understand the risk and inform them about mitigation and adaptation actions. Moreover, analyzing the technological, social and policy dimensions of thermal resilience is critical for climate-proofing buildings. This paper presents 10 questions that highlight the most important issues regarding the thermal resilience of buildings for occupants in the face of climate change. The proposed questions and answers aim to provide insights into current and future building thermal resilience research and applications, and more importantly to inspire new significant questions in the field.