Abstract The paper focuses on the evaluation of the impact on residential buildings of innovative control logics defined for a rational utilization of the electric loads and air-conditioning systems. The control logics are implementable thanks to a Decision Support and Energy Management Systems developed by the same authors and easily installable in new and still-existing houses. The paper shows how a significant reduction of the primary energy consumption can be obtained by controlling the air-conditioning units together with the other electric loads of the house. After having explained how the control logics operate, a simulation tool is described, developed for a preliminary evaluation of their effects on the energy consumptions of residential buildings in the design stage. An application of the simulation tool on a typical house, considering different scenarios and varying the climatic conditions and the energy performance class of the envelope, is presented. Finally, a measurement campaign on two real existing houses, equipped with the Decision Support and Energy Management System, is described, and the effects of the control logics are assessed.