Achieving carbon–neutral building stock by 2050 contributes to coping with the detrimental impacts of global warming since buildings account for almost 37% of final energy-related CO₂ emissions. This paper reviews the publications on carbon neutrality (CN) feasibility at both single and multi-building complex scales. Publications are retrieved from the Scopus database, and the snowball method is used to find the most relevant studies. The paper addresses the primary question: “Is it possible to reach the life cycle carbon neutrality of buildings?”. Various information such as building life cycle carbon assessment, building characteristics (usage type and number of stories), climate type, mitigation measures, and simulation results are extracted, classified, and analyzed. Technically, reaching CN is feasible, but it is challenging given the need to implement multiple mitigation measures simultaneously, especially in the regions with low emissions intensity of the electricity grid, and may not always be economically feasible. A lack of successful case studies for large multi-building complexes, such as cities, is evident in the literature. It can be attributed to the limited availability of input data for carbon assessments as well as the complexity of simulations. Knowledge gaps in the literature and suggestions for future works are also discussed in detail. Due to the small number of studies on the topic, conclusive paths to reach the CN of buildings, specific to different climates and types of buildings, remain unclear, and thus, further research is necessary.