Abstract Growing environmental concerns are driving the energy market toward the development of thermodynamic cycles to harness renewable energy and waste heat. This manuscript introduces the novel organic Rankine flash cycle, which combines the organic Rankine cycle with the trilateral cycle, merging their advantages in terms of high specific power output and low heat transfer irreversibility, respectively. By comparing the organic Rankine flash cycle to the organic flash cycle, it was found that the proposed architecture reaches a peak exergy efficiency at a more realistic value of two-phase expansion volume flow ratio, consistently achieves higher energy and exergy efficiencies, presents a lower cost, and is not constrained to operate close to the working fluid saturation temperature, promising easier operability. Considering pentane as working fluid, the exergy efficiency of the organic Rankine flash cycle is 18%p higher for a heat source temperature of 150 °C, 12%p for 175 °C, and 4%p for 200 °C. The attractive thermoeconomic performance of the proposed organic Rankine flash cycle highlights the potential of such a cycle as a new paradigm in the ORC panorama, encouraging further investigation towards practical demonstration.