This paper explores the implementation of the Building To Vehicle To Building (V2B2) scheme in European Countries, by evaluating the influence of weather conditions and local energy market prices on its energy and economic performance. The use of electric vehicles as energy vectors among buildings belonging to a virtual cluster is the key aspect of the V2B2 scheme: by exploiting mobile electric storage devices, renewable electricity produced by building integrated PV panels is shared among diverse users and consumed off-site. This novel energy management scheme has a twofold aim: i) promoting energy flexibility and efficiency in multiple buildings by improving the share of self-consumed renewable electricity at a cluster level and ii) reducing the interaction with the power grid. The proposed cluster includes two buildings, a house and an office space, and an electric vehicle, and it can be considered as the basic nucleus of human linked energy users. The energy and economic performance of the proposed V2B2 scheme highly depends on weather conditions and purchasing/selling electricity price. Therefore, to assess the impact of weather and energy prices on the system energy and economic performance, a comprehensive parametric analysis is conducted by varying the main design and operating parameters of the capacity of the key components of the investigated energy cluster, such as of buildings integrating PV panels and electric storage devices. The modelled and simulated scenarios refer to two different layouts simulated in several European cities, selected to consider different weather conditions and national electricity market prices. To identify the optimal V2B2 configurations, several energy and economic indicators of each simulated scenario are compared to a conventional reference one in which the novel energy management scheme is not implemented. Through the proposed V2B2 scheme, encouraging energy savings, from a minimum of 13.6% to a maximum of 71.2%, and economic outcomes are achieved.