Abstract During this industrialized era, consumption of high-speed diesel (HSD) is increasing rapidly in the power, transportation, agriculture, and other commercial sectors of Bangladesh, albeit a significant amount of HSD is imported from foreign countries. The fuel mono-dependency on imported HSD demands huge economic investment of any country that consequences a negative impact on the cash flow of the overall economy. This study emphasized the contribution of HSD from petroleum products in significant fields and provided the current scenario of diesel import. Besides fuel issues, the other major environmental concern of Bangladesh is tremendous carbon emission caused by the overuse of diesel that consequences severe environmental pollution. To minimize the investment in imported HSD as well as environmental pollution, an alternative fuel, biodiesel generation, has been proposed in this study. This study also projected the total approximate biodiesel production from chicken skin collected from the whole of Bangladesh. Besides, this study also predicted the possible amount of can be replaced by biodiesel from chicken skin and aimed at the cost reduction due to the replacement of diesel by biodiesel.