The Marine Stewardship Council is the leader in seafood ecolabel certification. Despite its high impact in promoting sustainable fishing and securing price premiums, a large proportion of fisheries withdraw from the scheme during or after certification. We, therefore, investigate the factors influencing the likelihood of withdrawal. To achieve this, we analysed publicly available information from 301 fisheries that have embarked on the certification process using survival analysis methods to investigate the withdrawal rate. It was found that the fishing gear used, and geographical location were the principal factors affecting the likelihood of withdrawal and that the risk of withdrawal is greatest during the full-assessment process and the first five years of certification. Our study also reviews the uneven global expansion of MSC ecolabelling by region and identifies factors that influence withdrawal and need to be considered in fisheries entering MSC certification.