An integrated modeling framework for investigating the application of solid boron powder injection for real-time surface conditioning of plasma-facing components in tokamak environments is presented. Utilizing the DIII-D impurity powder dropper setup, this study simulates B powder injection scenarios ranging from mg/s to tens of mg/s, corresponding to B flux rates of $10^{20}-10^{21}$ B/s in standard L-mode conditions. The comprehensive modeling approach combines EMC3-EIRENE for simulating the D plasma background and DIS for the ablation and transport of the B powder particles. The results show substantial transport of B to the inboard lower divertor, predominantly influenced by the main ion plasma flow. The dependency on powder particle size (5-250 $μ$m) was found to be insignificant for the scenario considered. The effects of erosion and redeposition were considered to reconcile the discrepancies with experimental observations, which saw substantial deposition on the outer divertor PFCs. For this purpose, the WallDYN3D code was updated to include B sources within the plasma domain and integrated into the modeling framework. The mixed-material migration modeling shows evolving B deposition patterns, suggesting the formation of mixed B-C layers or predominantly B coverage depending on the powder mass flow rate. While the modeling outcomes at lower B injection rates tend to align with experimental observations, the prediction of near-pure B layers at higher rates has yet to be experimentally verified in the C environment of the DIII-D tokamak. The extensive reach of B layers found in the modeling suggests the need for modeling that encompasses the entire wall geometry for more accurate experimental correlations. This integrated approach sets a precedent for analyzing and applying real-time in-situ boron coating techniques in advanced tokamak scenarios, potentially extendable to ITER.